Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Elena G, Varlamova"'
Autor:
Elena G. Varlamova, Vera P. Kuldaeva, Natalia N. Mitina, Maria S. Gavrish, Elena V. Kondakova, Victor S. Tarabykin, Alexei A. Babaev, Egor A. Turovsky
Publikováno v:
Cells, Vol 13, Iss 21, p 1747 (2024)
The mechanisms of epileptogenesis after brain injury, ischemic stroke, or brain tumors have been extensively studied. As a result, many effective antiseizure drugs have been developed. However, there are still many patients who are resistant to thera
Externí odkaz:
https://doaj.org/article/2ef3d3519f1b432c8e829e2f4c3a1d87
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1756 (2024)
Despite the successes in the prevention and treatment of strokes, it is still necessary to search for effective cytoprotectors that can suppress the damaging factors of cerebral ischemia. Among the known neuroprotectors, there are a number of drugs w
Externí odkaz:
https://doaj.org/article/7537d197ed264ef2b9f727122ee25008
Molecular Mechanisms of the Therapeutic Effect of Selenium Nanoparticles in Hepatocellular Carcinoma
Autor:
Elena G. Varlamova
Publikováno v:
Cells, Vol 13, Iss 13, p 1102 (2024)
This review describes and summarizes, for the first time, the molecular mechanisms of the cytotoxic effect of selenium nanoparticles of various origins on hepatocellular carcinoma cells. The text provides information from recent years indicating the
Externí odkaz:
https://doaj.org/article/a128fff2e49645f0b7bbd5e131dca2fe
Autor:
Elena G. Varlamova, Michail Victorovich Goltyaev, Vladimir Vladimirovich Rogachev, Sergey V. Gudkov, Elena V. Karaduleva, Egor A. Turovsky
Publikováno v:
Cells, Vol 12, Iss 23, p 2723 (2023)
For the first time, based on the expression analysis of a wide range of pro- and anti-fibrotic, pro- and anti-inflammatory, and pro- and anti-apoptotic genes, key markers of endoplasmic reticulum stress (ER-stress), molecular mechanisms for the regul
Externí odkaz:
https://doaj.org/article/5d67a4df3ae1432093ab990482e33e9e
Publikováno v:
Applied Sciences, Vol 13, Iss 19, p 10763 (2023)
The anti-cancer effects of selenium sources are well known. Among other things, selenium has been shown to have a pleiotropic effect, causing cancer cell death without affecting the healthy cell’s viability, or, in the case of brain cells, has a cy
Externí odkaz:
https://doaj.org/article/163322590b5c4dc28fbb7c9b9fc9cdd7
Publikováno v:
Biology, Vol 12, Iss 9, p 1207 (2023)
Genetic disorders affecting the functioning of the brain lead not only to the development of numerous hereditary diseases but also to the development of neurodegenerative and cognitive disorders. The result of this may be the disability of part of th
Externí odkaz:
https://doaj.org/article/32a1948498114de5bbe9c18f2f63f943
Autor:
Elena G. Varlamova, Venera V. Khabatova, Sergey V. Gudkov, Egor Y. Plotnikov, Egor A. Turovsky
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2477 (2022)
The neuroprotective effect of the natural antioxidant taxifolin (TAX) is well known for ischemic pathologies. However, the limitations of taxifolin application are described—poor solubility, low ability to penetrate the blood–brain barrier, and s
Externí odkaz:
https://doaj.org/article/ec227c2fce6f4e8d9eded7d15e023da4
Publikováno v:
Biology, Vol 11, Iss 6, p 811 (2022)
It is known that seven mammalian selenoproteins are localized in the endoplasmic reticulum: SELENOM, SELENOT, SELENOF, SELENOK, SELENOS, SELENON, and DIO2. Among them, SELENOM and SELENOT are the least studied; therefore, the study of their function
Externí odkaz:
https://doaj.org/article/86185035ca494e63924758dcbe9b03fa
Autor:
Egor A. Turovsky, Elena G. Varlamova
Publikováno v:
Biology, Vol 10, Iss 8, p 743 (2021)
To date, there are practically no data on the mechanisms of the selenium nanoparticles action on calcium homeostasis, intracellular signaling in cancer cells, and on the relationship of signaling pathways activated by an increase in Ca2+ in the cytos
Externí odkaz:
https://doaj.org/article/44546908fbb14240b0d31db45feefd43
Publikováno v:
International journal of molecular sciences. 23(24)
A defection of blood circulation in the brain leads to ischemia, damage, and the death of nerve cells. It is known that individual populations of GABAergic neurons are the least resistant to the damaging factors of ischemia and therefore they die fir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d315406dcf3cce6f4c0f41ad3f0781b3
https://pubmed.ncbi.nlm.nih.gov/36555318
https://pubmed.ncbi.nlm.nih.gov/36555318