Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Elena Fonfría"'
Publikováno v:
Journal of Neuroscience Research. 79:545-553
Contract grant sponsor: Ministry of Health; Contract grant number: FIS 00/1094, 01/1318; Contract grant sponsor: Ministry of Science and Technology (FEDER); Contract grant number: SAF 2003-04930; Contract grant sponsor: CIRIT, Generalitat de Cataluny
Autor:
Elena Fonfria, Elizabeth Marks, Lisa-Marie Foulkes, Rebecca Schofield, Daniel Higazi, Sam Coward, Alistair Kippen
Publikováno v:
Toxins, Vol 15, Iss 5, p 314 (2023)
Botulinum neurotoxins (BoNTs) are important therapeutic agents. The in vivo median lethal dose (LD50) assay has been commonly used to measure the potency of BoNT commercial preparations. As an alternative, we developed cell-based assays for abobotuli
Externí odkaz:
https://doaj.org/article/3ffd446e80d14f4daed9b07ee3ec6b6d
Autor:
Zoila Babot, Iolanda Vendrell, Cristina Suñol, Elena Fonfría, Daniel A. García, Nancy Herrera, Mireia Galofré, Susana Iraola
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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El pdf del artículo es la versión post-print.
Neurotoxicology considers that chemicals perturb neurological functions by interfering with the structure or function of neural pathways, circuits and systems. Using in vitro methods for neurotoxic
Neurotoxicology considers that chemicals perturb neurological functions by interfering with the structure or function of neural pathways, circuits and systems. Using in vitro methods for neurotoxic
Publikováno v:
Journal of neuroscience research. 79(4)
Cerebellar granule cells are targeted selectively by mercury compounds in vivo. Despite the affinity of mercury for thiol groups present in all cells, the molecular determinant(s) of selective cerebellar degeneration remain to be elucidated fully. We
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
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7 pages, 4 figures, 2 tables.-- PMID: 12614680 [PubMed].-- Printed version published Mar 21, 2003.
The neurotoxic organochlorine pesticides γ-hexachlorocyclohexane, α-endosulfan and dieldrin induce in mammals a hyperexcitability syndrome accom
The neurotoxic organochlorine pesticides γ-hexachlorocyclohexane, α-endosulfan and dieldrin induce in mammals a hyperexcitability syndrome accom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca864bf913532821feb439d74b60bcc8
http://hdl.handle.net/10261/20225
http://hdl.handle.net/10261/20225
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Mercury compounds are neurotoxic compounds with a great specificity for cerebellar granule cells. The interaction of mercury compounds with proteins in the central nervous system may underlie some of their effects on neurotransmission. In this work w
Autor:
Juliette Duchesne De Lamotte, Sylvain Roqueviere, Hélène Gautier, Elsa Raban, Céline Bouré, Elena Fonfria, Johannes Krupp, Camille Nicoleau
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
Botulinum neurotoxins (BoNTs) are zinc metalloproteases that block neurotransmitter release at the neuromuscular junction (NMJ). Their high affinity for motor neurons combined with a high potency have made them extremely effective drugs for the treat
Externí odkaz:
https://doaj.org/article/e8bcdfa111d440ada5678e954a4074af
Publikováno v:
Toxins, Vol 10, Iss 7, p 278 (2018)
Botulinum neurotoxins (BoNTs) are highly successful protein therapeutics. Over 40 naturally occurring BoNTs have been described thus far and, of those, only 2 are commercially available for clinical use. Different members of the BoNT family present d
Externí odkaz:
https://doaj.org/article/02afe7ef822b4eb18dfa1c0fa4076e68