Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Elena Farcas"'
Autor:
Aurelia Coroian, Adriana Chicinas, Camelia Raducu, Bianca Ionescu, Beniamin Mihon, Malina Puia, Elena Farcas, Eugenia Butucel, Helga Puskas, Adina Lia Longodor
Publikováno v:
Banat's Journal of Biotechnology. :5-10
Publikováno v:
Talanta. 188:516-521
Capillary electrophoresis (CE) instrument was used for the generation of a robust and reliable nanoreactor for enzymatic assays in the context of antithrombotic drug screening. The activity of the screened molecules was monitored in a quick and fully
Autor:
Tania Furst, Brigitte Evrard, Elena Farcas, Antoine Frère, Virginie Bettonville, Géraldine Piel, Anne-Catherine Servais, Anna Lechanteur, Marianne Fillet
Publikováno v:
ELECTROPHORESIS. 37:2685-2691
Small interfering RNA (siRNA) inducing gene silencing has great potential to treat many human diseases. To ensure effective siRNA delivery, it must be complexed with an appropriate vector, generally nanoparticles. The nanoparticulate complex requires
Autor:
Caroline Lamalle, Anne-Catherine Servais, Patrice Chiap, Lionel Pochet, Marianne Fillet, Elena Farcas
Publikováno v:
ELECTROPHORESIS. 37:248-255
In this study, a fully automated incapillary system was developed to monitor the activity of CYP1A1 (Cytochrome P450, family 1, subfamily A, polypeptide 1) in physiological conditions. Ethoxycoumarin, the selected substrate, undergoes an inline biore
Autor:
Elena Farcas, Isabelle Roland, Radu-Cristian Moldovan, Marianne Fillet, Jacques Crommen, Anne-Catherine Servais
Publikováno v:
Journal of Chromatography A. 1363:178-182
The ophthalmic solution of voriconazole, i.e. (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol, made from an injection formulation which also contains sulfobutylether-β-cyclodextrin sodium salt as an exci
Autor:
Marianne Fillet, Elena Farcas, Anne Catherine Servais, Lionel Pochet, Julien Hanson, Charlotte Bouckaert
Publikováno v:
Analytica chimica acta. 984
With the emergence of more challenging targets, a relatively new approach, fragment-based drug discovery (FBDD), proved its efficacy and gained increasing importance in the pharmaceutical industry. FBDD identifies low molecular-weight (MW) ligands (f
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 144
Capillary Electrophoresis is a very efficient and resolutive separation technique used for many years in the analytical field. Despite all its assets, CE remains poorly used in drug discovery. This can be explained by the relatively low number of exp
Autor:
Marianne Fillet, Katina Sourou Sylvestre Dossou, Jacques Crommen, Patrice Chiap, Bezhan Chankvetadze, Anne-Catherine Servais, Elena Farcas
Publikováno v:
Journal of Chromatography A. 1234:56-63
The LC enantioseparation of chiral acidic and zwitterionic drugs selected as model compounds was optimized using chlorine containing cellulose based chiral stationary phases and polar organic mobile phases. The main solvent of the mobile phase was ac
Autor:
Caroline Lamalle, Marianne Fillet, Gerhardus J. de Jong, Ines Fradi, Anne-Catherine Servais, Mohamed Kallel, Jacques Crommen, Marie-Laure Yans, Azza Ben Said, Amir Prior, Elena Farcas, Govert W. Somsen
Publikováno v:
Fradi, I, Farcasa, E, Ben Said, A, Yans, M-L, Lamalle, C, Somsen, G W, Prior, A, de Jong, G J, Kallel, M, Crommen, J, Servais, A-C & Fillet, M 2014, ' In-capillary derivatization with (−)-1-(9-fluorenyl)ethyl chloroformate as chiral labeling agent for the electrophoretic separation of amino acids ', Journal of Chromatography A, vol. 1363, pp. 338-347 . https://doi.org/10.1016/j.chroma.2014.07.022
Journal of Chromatography A, 1363, 338-347. Elsevier
Journal of Chromatography A, 1363, 338-347. Elsevier
An original micellar electrokinetic chromatography (MEKC) method using in-capillary derivatization with a chiral labeling reagent was developed for the separation of amino acid (AA) derivatives. The potential of (-)-1-(9-fluorenyl)-ethyl chloroformat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94d07970890fcfcaf76e62b0b1222a81
https://research.vu.nl/en/publications/514bdecf-1b6b-48a9-89cb-fd0ad68b3bdc
https://research.vu.nl/en/publications/514bdecf-1b6b-48a9-89cb-fd0ad68b3bdc
Autor:
Virginie Bettonville, Lionel Pochet, Elena Farcas, Marianne Fillet, Charlotte Bouckaert, Anne-Catherine Servais
Publikováno v:
Talanta. 116
Developing an EMMA method for enzymatic assay remains a challenge, particularly using UV detection. Indeed, it is necessary to optimize the separation conditions while allowing the enzymatic reaction to occur within the capillary respecting kinetic c