Fusion InPipe, an integrative pipeline for gene fusion detection from RNA-seq data in acute pediatric leukemia

Autor: Clara Vicente-Garcés, Joan Maynou, Guerau Fernández, Elena Esperanza-Cebollada, Montserrat Torrebadell, Albert Català, Susana Rives, Mireia Camós, Nerea Vega-García

Publikováno v: Frontiers in Molecular Biosciences, Vol 10 (2023)

RNA sequencing (RNA-seq) is a reliable tool for detecting gene fusions in acute leukemia. Multiple bioinformatics pipelines have been developed to analyze RNA-seq data, but an agreed gold standard has not been established. This study aimed to compare

Externí odkaz: https://doaj.org/article/df8157a4ae75472f8546d2ee3c5bd548

Measurable Residual Disease Assessed by Flow-Cytometry Is a Stable Prognostic Factor for Pediatric T-Cell Acute Lymphoblastic Leukemia in Consecutive SEHOP Protocols Whereas the Impact of Oncogenetics Depends on Treatment

Autor: Nerea Vega-García, Sara Perez-Jaume, Elena Esperanza-Cebollada, Clara Vicente-Garcés, Montserrat Torrebadell, Antonio Jiménez-Velasco, Margarita Ortega, Marta Llop, Lorea Abad, José Manuel Vagace, Alfredo Minguela, Marta Pratcorona, Joaquín Sánchez-Garcia, Clara B. García-Calderón, María Teresa Gómez-Casares, Estela Martín-Clavero, Adela Escudero, Marta Riñón Martinez-Gallo, Luz Muñoz, María Rosario Velasco, Marina García-Morin, Albert Català, Antonia Pascual, Pablo Velasco, José Mª. Fernández, Alvaro Lassaletta, José Luis Fuster, Isabel Badell, Águeda Molinos-Quintana, Antonio Molinés, Pilar Guerra-García, Antonio Pérez-Martínez, Miriam García-Abós, Reyes Robles Ortiz, Sandra Pisa, Rosa Adán, Cristina Díaz de Heredia, José Luis Dapena, Susana Rives, Manuel Ramírez-Orellana, Mireia Camós

Publikováno v: Frontiers in Pediatrics, Vol 8 (2021)

Robust and applicable risk-stratifying genetic factors at diagnosis in pediatric T-cell acute lymphoblastic leukemia (T-ALL) are still lacking, and most protocols rely on measurable residual disease (MRD) assessment. In our study, we aimed to analyze

Externí odkaz: https://doaj.org/article/76d44086f8a049c3816cf6758487be24

Helpful Criteria When Implementing NGS Panels in Childhood Lymphoblastic Leukemia

Autor: Rocío Benito, Montserrat Torrebadell, Antonio Jiménez-Velasco, Joaquín Sánchez, José María Fernández, Adrián Montaño, Eva Barragán, Margarita Ortega, Elena Esperanza-Cebollada, Marta Martín-Izquierdo, Nerea Vega-García, Jesús M. Hernández-Rivas, Joan Maynou, Marta Llop, Jesus M Hernández-Sánchez, Manuel Ramírez, Susana Riesco, Cristina Robledo, Alvaro Lassaletta, Mireia Camós, José Cervera, Clara Vicente-Garcés, Javier Alonso, Alfredo Minguela, José Luis Dapena, Susana Rives, Guerau Fernandez

Publikováno v: Journal of Personalized Medicine, Vol 10, Iss 244, p 244 (2020)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Repisalud
Instituto de Salud Carlos III (ISCIII)
Scientia
Journal of Personalized Medicine
Volume 10
Issue 4

The development of Next-Generation Sequencing (NGS) has provided useful diagnostic, prognostic, and therapeutic strategies for individualized management of B-cell precursor acute lymphoblastic leukemia (BCP-ALL) patients. Consequently, NGS is rapidly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1545e3b9e353e3aa5418deaeff6f338
https://www.mdpi.com/2075-4426/10/4/244

PB1700: GENOMIC CHARACTERIZATION OF CHILDHOOD B-OTHER ACUTE LEUKEMIA PATIENTS BY RNA SEQUENCING IN A SINGLE CENTER

Autor: Clara Vicente Garcés, Guerau Fernández, Elena Esperanza Cebollada, Susana Rives, Jose Luis Dapena, Mireia Camos Guijosa, Nerea Vega García

Publikováno v: HemaSphere, Vol 7, p e51978b7 (2023)

Externí odkaz: https://doaj.org/article/2baccc3bf0e34015aec6a99b3d15bfff