Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Elena E. Ustinova"'
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56886 (2013)
Paclitaxel (Pac) is an antitumor agent that is widely used for treatment of solid cancers. While being effective as a chemotherapeutic agent, Pac in high doses is neurotoxic, specifically targeting sensory innervations. In view of these toxic effects
Externí odkaz:
https://doaj.org/article/a359b9eee8934eb7b63ed93c687571f3
Autor:
Elena E. Ustinova, Mingzhang Guo, John H. Tinsley, Mack H. Wu, Primal de Lanerolle, Sarah Y. Yuan, Wenjuan Xu
Publikováno v:
Circulation Research. 90:1214-1221
Neutrophil-induced coronary microvascular leakage represents an important pathophysiological consequence of ischemic and inflammatory heart diseases. The precise mechanism by which neutrophils regulate endothelial barrier function remains to be estab
Publikováno v:
The Journal of Physiology. 532:785-791
Integrin-mediated endothelial cell-extracellular matrix adhesion plays a critical role in maintaining the structural integrity of microvascular walls. The aim of this study was to evaluate the impact of specific integrin extracellular domain binding
Publikováno v:
Europe PubMed Central
We investigated the effects of diabetes mellitus and antioxidant treatment on the sensory and reflex function of cardiac chemosensory nerves in rats. Diabetes was induced by streptozotocin (STZ; 85 mg/kg ip). Subgroups of sham- and STZ-treated rats w
Autor:
Mack H. Wu, Amy C. Taulman, Wenjuan Xu, John H. Tinsley, Elena E. Ustinova, Sarah Y. Yuan, Ferenc L. Korompai
Publikováno v:
Circulation Research. 87:412-417
Abstract —The functional disturbance of microvasculature is recognized as an initiating mechanism that underlies the development of various diabetic complications. Although a causal relationship between microvascular leakage and tissue damage has b
Autor:
Elena E. Ustinova, Harold D. Schultz
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 23:700-708
1. Myocardial ischaemia and reperfusion can evoke excitation of cardiac vagal afferent nerve endings and activation of a cardiogenic depressor reflex (Bezold-Jarisch effect). We postulate that oxygen free radicals, which are well known to be produced
Publikováno v:
Cardiovascular Research. 30:55-63
Objectives: Ischemia of the myocardium stimulates cardiac sensory nerve endings resulting in the local release of neuropeptides. The significance of the release of neuropeptides, such as substance P (SP), for the function of the heart during ischemia
Autor:
Jocelyn J. Fitzgerald, William C. de Groat, Elena E. Ustinova, Michael A. Pezzone, Kevin B. Koronowski
Publikováno v:
Autonomic neuroscience : basicclinical. 173(1-2)
This study examined the contribution of mast cells to colon-bladder cross organ sensitization induced by colon irritation with trinitrobenzene sulfonic acid (TNBS-CI). In urethane anesthetized rats 12 days after TNBS-CI, the voiding interval was redu
Autor:
Elena E. Ustinova, Harold D. Schultz
Publikováno v:
Circulation Research. 74:895-903
Myocardial ischemia and reperfusion can evoke excitation of cardiac vagal afferent nerve endings and activation of a cardiogenic depressor reflex (Bezold-Jarisch effect). We postulate that oxygen-derived free radicals, which are well known to be prod
Publikováno v:
The FASEB Journal. 25