Endothelial Cell Dysfunction in Viral Hemorrhage and Edema

Autor: Erich Reuter Mackow, Elena E Gorbunova, Irina N. Gavrilovskaya

Publikováno v: Frontiers in Microbiology, Vol 5 (2015)

The endothelium maintains a vascular barrier by controlling platelet and immune cell interactions, capillary tone and interendothelial cell adherence. Here we suggest common elements in play during viral infection of the endothelium that alter normal

Externí odkaz: https://doaj.org/article/a3705a72b49441a7b7653da39d3a1758

Recombinant ACE2 Expression Is Required for SARS-CoV-2 To Infect Primary Human Endothelial Cells and Induce Inflammatory and Procoagulative Responses

Autor: Jonas Nascimento Conde, William R. Schutt, Elena E. Gorbunova, Erich R. Mackow

Publikováno v: mBio, Vol 11, Iss 6 (2020)

ABSTRACT SARS-CoV-2 causes COVID-19, an acute respiratory distress syndrome (ARDS) characterized by pulmonary edema, viral pneumonia, multiorgan dysfunction, coagulopathy, and inflammation. SARS-CoV-2 uses angiotensin-converting enzyme 2 (ACE2) recep

Externí odkaz: https://doaj.org/article/8e23eab6ee5b4c3d90257cf05dce86f6

Phenological shifts of abiotic events, producers and consumers across a continent

Autor: Svetlana Igosheva, Natalia Belyaeva, Aleksandra Krasnopevtseva, Aleksey Tomilin, Yuri Buyvolov, Tatiana Akimova, Aleksey Kudryavtsev, Irina Kozyr, Olga Rozhkova, Olga Ermakova, Yurij Tyukh, Evgeniy A. Davydov, Ozodbek Abduraimov, Elvira Kotlugalyamova, Mykhailo Motruk, Elena B. Pospelova, Natalia Korotkikh, Vladislav Timoshkin, Rustam Sibgatullin, Irina Fedchenko, Dmitrij Golovcov, Andrey S. Kuznetsov, Irina Nesterova, Tatyana Zubina, Galina Sokolova, Yuri Bykov, Miroslav Babushkin, Tomas Roslin, Helen Korolyova, Elena Smirnova, Sergei Stepanov, S. Sazonov, Evgeniy Meyke, Murad Kurbanbagamaev, Svetlana Bondarchuk, Sergey Kossenko, Darya Kiseleva, Vasyl Shevchyk, Alexander Hritankov, Elena Sitnikova, Oleg Bakin, Tatyana Gordeeva, Ludmila Dostoyevskaya, Irina Gaydysh, Margarita Kupriyanova, Coong Lo, Yuliia Kulsha, Vladimir Van, Elena Bochkareva, Mirabdulla Turgunov, Tatiana Filatova, Marina Yakovleva, Lilija Sultangareeva, Fedor Kazansky, P. D. Lebedev, Irina Megalinskaja, Akynaly Dubanaev, Elena Chakhireva, Elena Diadicheva, Aleksandra Esengeldenova, Juri Kurhinen, Tamara Nezdoliy, Maria Hällfors, Maxim Antipin, Alla Kozurak, Kirill Litvinov, Nicolay Zelenetskiy, Leonid Kolpashikov, Ksenia Shalaeva, Elena Andreeva, Vladimir Yakovlev, Ludmila Gromyko, Miroslava Sahnevich, Tatiana Polyanskaya, Viktor Mamontov, Valeri Sanko, Evgeniya Kaygorodova, Tatiana Tertitsa, Andrey Zahvatov, Nadezhda Kuyantseva, Anatoly Bobretsov, Oleg Mitrofanov, Elena Shujskaja, Aleksandr Ananin, Viktor Teplov, Valentina Teplova, Alexander Sukhov, Vladimir Hohryakov, Natalya Ivanova, Nadezhda Kutenkova, Yury Kalinkin, Gleb Tikhonov, Lidiya Makovkina, Lidia Epova, Alexey Pavlov, Anatolii Zheltukhin, Uliya Ivanova, María del Mar Delgado, Aleksandr Myslenkov, Evgeniya Bukharova, Guzalya Suleymanova, Gennady Bogdanov, Natalia Luzhkova, Irina Rybnikova, Nadezhda Goncharova, Nikolay Volodchenkov, Nataliya Skok, Yuri Rozhkov, Viktorija Teleganova, Aleksandr Minin, Vladimir Bobrov, Zoya Drozdova, Nina Belova, Irina Prokosheva, Svetlana Babina, Lidia Vetchinnikova, Svetlana Mayorova, Artur Meydus, Evgeny Kozlovsky, Violetta Strekalovskaya, Yurij Yarema, Ilya Prokhorov, Elena Ignatenko, Nadezhda Cherenkova, Tatyana Niroda, Vitalіy Stratiy, Valery Zakharov, Olga Chashchina, Oleg Evstigneev, Sergey Elsukov, Maksim Shashkov, Evgenii Korobov, Sergej Shubin, Ivan Putrashyk, Darya Panicheva, Klara Pavlova, Anatoliy Kutenkov, Ludmila Tselishcheva, Elena Ershkova, Vadim Bobrovskyi, Dmitry Tirski, Laura H. Antão, Vladimir Sopin, Olga Kuberskaya, Svetlana Skorokhodova, Svetlana Drovnina, Vladislav Vinogradov, Natalia Andriychuk, Sergey Kruglikov, Anatoliy Gavrilov, Anatoliy Vekliuk, Olga S Ermakova, Aleksandra Vasina, Anna Barabancova, Muzhigit Akkiev, Vladimir Kozsheechkin, Andrei Sivkov, Otso Ovaskainen, Polina Van, Azizbek Mahmudov, Anastasia A. Knorre, Julia Raiskaya, Evgeniya Bisikalova, Inna Basilskaja, Svetlana Chuhontseva, Anatoliy Shcherbakov, Vladimir Bolshakov, Alexander Samoylov, Igor N. Pospelov, Sergej Chistjakov, Viktor Demchenko, Natalia Nemtseva, Sergei Podolski, Alena Butunina, Gennadiy Kosenkov, Tatiana Novikova, Aleksandr Dobrolyubov, Andrej Tolmachev, Oksana Yantser, Yuriy Dubrovsky, Lyudmila Puchnina, Sergey Gashev, Natalia Sikkila, Violetta Fedotova, Zoya Selyunina, Evgeniy Larin, Inna Voloshina, Marina Rudenko, Elena Kulebyakina, Natalja Polikarpova, Aleksander Vasin, Yurii Spasovski, Olga Adrianova, Vitaly Grishchenko, Konstantin Arzamascev, Eliezer Gurarie, Svetlana Rykova, Elena E. Gorbunova, Nina Nasonova, Inna Sapelnikova, Marina Abadonova, Eugenia Yablonovska-Grishchenko, Anna Buyvolova, Tatjana Bespalova, Tura Xoliqov

Publikováno v: Nature Climate Change
Digital.CSIC. Repositorio Institucional del CSIC
instname

Ongoing climate change can shift organism phenology in ways that vary depending on species, habitats and climate factors studied. To probe for large-scale patterns in associated phenological change, we use 70,709 observations from six decades of syst

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c46db2348d6d4fc610a66c1622fed21f
https://doi.org/10.1038/s41558-020-00967-7

Differences in spatial versus temporal reaction norms for spring and autumn phenological events

Autor: Olga Rozhkova, Elena Kulebyakina, Svetlana Babina, Olga Ermakova, Natalja Polikarpova, Anatolii Zheltukhin, Vladimir Bolshakov, Violetta Strekalovskaya, Olga Kuberskaya, Natalia Belyaeva, Aleksander Vasin, Darya Panicheva, Anatoliy Kutenkov, Elvira Kotlugalyamova, Artur Meydus, Aleksey Tomilin, Ludmila Tselishcheva, Mykhailo Motruk, Evgeny Kozlovsky, Yuri Buyvolov, Elena B. Pospelova, Natalia Korotkikh, Vadim Bobrovskyi, Anna Barabancova, Vitalіy Stratiy, Natalia Andriychuk, Margarita Kupriyanova, Dmitry Tirski, Klara Pavlova, Elena Andreeva, Tatyana Gordeeva, Ludmila Dostoyevskaya, Irina Kozyr, Yuriy Dubrovsky, Zoya Selyunina, Andrei Sivkov, Muzhigit Akkiev, Vladimir Kozsheechkin, Nataliya Skok, Viktorija Teleganova, Azizbek Mahmudov, Yurij Yarema, Elena Ershkova, Rustam Sibgatullin, Dmitrij Golovcov, Kirill Litvinov, Aleksey Kudryavtsev, Nadezhda Kuyantseva, Elena Shujskaja, Anastasia A. Knorre, Coong Lo, Mirabdulla Turgunov, Tatiana Filatova, Yurij Tyukh, Gennadiy Kosenkov, Aleksandra Esengeldenova, Lyudmila Puchnina, Tatyana Zubina, Alla Kozurak, Vladimir Hohryakov, Maxim Antipin, Svetlana Mayorova, Nikolay Volodchenkov, Eugenia Yablonovska-Grishchenko, Miroslava Sahnevich, Vladimir Yakovlev, Ludmila Gromyko, Tatiana Polyanskaya, Tatiana Novikova, Alexander Samoylov, Aleksandr Dobrolyubov, Helen Korolyova, Nicolay Zelenetskiy, Leonid Kolpashikov, S. Sazonov, Polina Van, Olga Adrianova, Evgeniy Meyke, Viktor Teplov, Valeri Sanko, Ilya Prokhorov, Elena Ignatenko, Tatyana Niroda, Nina Belova, Andrey Zahvatov, Aleksandr Ananin, Vitaly Grishchenko, Konstantin Arzamascev, María del Mar Delgado, Irina Prokosheva, Aleksandr Myslenkov, Yuri Rozhkov, Nadezhda Cherenkova, Svetlana Chuhontseva, Anna Buyvolova, Sergey Gashev, Natalya Ivanova, Nadezhda Kutenkova, Anatoliy Shcherbakov, Evgeniya Kaygorodova, Valentina Teplova, Nadezhda Goncharova, Oleg Mitrofanov, Svetlana Igosheva, Igor N. Pospelov, Sergej Chistjakov, Oleg Evstigneev, Sergey Elsukov, Maksim Shashkov, Ozodbek Abduraimov, Vladislav Timoshkin, Vasyl Shevchyk, Irina Fedchenko, Otso Ovaskainen, Galina Sokolova, Sergei Stepanov, Aleksandr Minin, Vladimir Bobrov, Sergey Kruglikov, Valery Zakharov, Miroslav Babushkin, Murad Kurbanbagamaev, Svetlana Bondarchuk, Lidiya Makovkina, Sergej Shubin, Zoya Drozdova, Tatjana Bespalova, Olga Chashchina, Yury Kalinkin, Natalia Sikkila, Alexander Hritankov, Ivan Putrashyk, Tura Xoliqov, Anatoliy Vekliuk, Evgenii Korobov, Alexey Pavlov, Yuliia Kulsha, Aleksandra Vasina, Aleksandra Krasnopevtseva, Marina Yakovleva, Lilija Sultangareeva, P. D. Lebedev, Gleb Tikhonov, Anatoly Bobretsov, Anatoliy Gavrilov, Andrej Tolmachev, Irina Megalinskaja, Uliya Ivanova, Viktor Mamontov, Lidia Epova, Gennady Bogdanov, Natalia Nemtseva, Tatiana Akimova, Sergei Podolski, Olga S Ermakova, Tatiana Tertitsa, Guzalya Suleymanova, Alexander Sukhov, Alena Butunina, Natalia Luzhkova, Tomas Roslin, Oksana Yantser, Evgeniya Bisikalova, Irina Rybnikova, Evgeniya Bukharova, Vladimir Sopin, Lidia Vetchinnikova, Darya Kiseleva, Inna Basilskaja, Evgeniy A. Davydov, Violetta Fedotova, Yuri Bykov, Vladimir Van, Sergey Kossenko, Juri Kurhinen, Elena Smirnova, Elena Bochkareva, Elena Sitnikova, Elena Chakhireva, Elena Diadicheva, Viktor Demchenko, Andrey S. Kuznetsov, Irina Nesterova, Fedor Kazansky, Irina Gaydysh, Tamara Nezdoliy, Svetlana Skorokhodova, Marina Abadonova, Svetlana Drovnina, Akynaly Dubanaev, Oleg Bakin, Ksenia Shalaeva, Eliezer Gurarie, Svetlana Rykova, Elena E. Gorbunova, Nina Nasonova, Inna Sapelnikova, Evgeniy Larin, Inna Voloshina, Marina Rudenko, Yurii Spasovski, Julia Raiskaya, Vladislav Vinogradov

Publikováno v: PNAS
Scopus
Proceedings of the National Academy of Sciences of the United States of America
RUO: Repositorio Institucional de la Universidad de Oviedo
Universidad de Oviedo (UNIOVI)
RUO. Repositorio Institucional de la Universidad de Oviedo
instname

European Research Council (ERC) Starting Grant 205905 (to O.O.) and Synergy Grant 856506—LIFEPLAN (to O.O. and T.R.); Spanish Ramón y Cajal Grant RYC-2014-16263 (to M.M.D.) (...)
Delgado, M.D.M., Roslin, T., Tikhonov, G., Meyke, E., Lo, C., G

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cad5b133b1596f26eec15f00d40b3733
https://doi.org/10.1073/pnas.2002713117

Powassan Viruses Spread Cell to Cell During Direct Isolation from Ixodes Ticks and Persistently Infect Human Brain Endothelial Cells and Pericytes

Autor: Jonas N. Conde, Grace Himmler, William R. Schutt, Hwan Keun Kim, Nicholas Saladino, Santiago Sanchez-Vicente, Elena E. Gorbunova, Jorge L. Benach, Erich R. Mackow, Megan C. Mladinich

Publikováno v: J Virol

Powassan viruses (POWVs) are neurovirulent tick-borne flaviviruses emerging in the Northeastern U.S., with a 2% prevalence in Long Island (LI) deer ticks (Ixodes scapularis). POWVs are transmitted in as little as 15 minutes of a tick bite, and enter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3292be9ab9872c57d3e713de5b458b66
https://doi.org/10.1101/2021.09.30.462684