Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Elena Díaz-Casado"'
Autor:
Pilar González-García, María Elena Díaz-Casado, Agustín Hidalgo-Gutiérrez, Laura Jiménez-Sánchez, Mohammed Bakkali, Eliana Barriocanal-Casado, Germaine Escames, Riccardo Zenezini Chiozzi, Franziska Völlmy, Esther A. Zaal, Celia R. Berkers, Albert J.R. Heck, Luis C. López
Publikováno v:
Redox Biology, Vol 55, Iss , Pp 102403- (2022)
Defects in Coenzyme Q (CoQ) metabolism have been associated with primary mitochondrial disorders, neurodegenerative diseases and metabolic conditions. The consequences of CoQ deficiency have not been fully addressed, and effective treatment remains c
Externí odkaz:
https://doaj.org/article/a2808f9af5f749cfa28f555ecb1b8d8d
Autor:
Agustín Hidalgo‐Gutiérrez, Eliana Barriocanal‐Casado, Mohammed Bakkali, M Elena Díaz‐Casado, Laura Sánchez‐Maldonado, Miguel Romero, Ramy K Sayed, Cornelia Prehn, Germaine Escames, Juan Duarte, Darío Acuña‐Castroviejo, Luis C López
Publikováno v:
EMBO Molecular Medicine, Vol 11, Iss 1, Pp 1-18 (2018)
Abstract Coenzyme Q (CoQ) deficiency has been associated with primary defects in the CoQ biosynthetic pathway or to secondary events. In some cases, the exogenous CoQ supplementation has limited efficacy. In the Coq9R239X mouse model with fatal mitoc
Externí odkaz:
https://doaj.org/article/9013018b61324fb0803832ef7595dea9
Autor:
Agustín Hidalgo-Gutiérrez, Eliana Barriocanal-Casado, María Elena Díaz-Casado, Pilar González-García, Riccardo Zenezini Chiozzi, Darío Acuña-Castroviejo, Luis Carlos López
Publikováno v:
Biomedicines, Vol 9, Iss 10, p 1457 (2021)
Primary mitochondrial diseases are caused by mutations in mitochondrial or nuclear genes, leading to the abnormal function of specific mitochondrial pathways. Mitochondrial dysfunction is also a secondary event in more common pathophysiological condi
Externí odkaz:
https://doaj.org/article/29411af8ce9c4e47b9a63df8169739f7
Autor:
Pilar González-García, Eliana Barriocanal-Casado, María Elena Díaz-Casado, Sergio López-Herrador, Agustín Hidalgo-Gutiérrez, Luis C. López
Publikováno v:
Antioxidants, Vol 10, Iss 11, p 1687 (2021)
Coenzyme Q (CoQ) is a vital lipophilic molecule that is endogenously synthesized in the mitochondria of each cell. The CoQ biosynthetic pathway is complex and not completely characterized, and it involves at least thirteen catalytic and regulatory pr
Externí odkaz:
https://doaj.org/article/a1125c1a52ef4f1eb8439aceaba38194
Autor:
Elena Díaz-Casado, Ricardo Gómez-Nieto, José M de Pereda, Luis J Muñoz, María Jara-Acevedo, Dolores E López
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231603 (2020)
[This corrects the article DOI: 10.1371/journal.pone.0229953.].
Externí odkaz:
https://doaj.org/article/8ffba8b4ead148ae9e40660735764ddb
Autor:
Elena Díaz-Casado, Ricardo Gómez-Nieto, José M de Pereda, Luis J Muñoz, María Jara-Acevedo, Dolores E López
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229953 (2020)
Epilepsy is a complex neurological disorder characterized by sudden and recurrent seizures, which are caused by various factors, including genetic abnormalities. Several animal models of epilepsy mimic the different symptoms of this disorder. In part
Externí odkaz:
https://doaj.org/article/608017aea19747e9aed510e0ab1116f7
Autor:
Agustín Hidalgo-Gutiérrez, Pilar González-García, María Elena Díaz-Casado, Eliana Barriocanal-Casado, Sergio López-Herrador, Catarina M. Quinzii, Luis C. López
Publikováno v:
Antioxidants, Vol 10, Iss 4, p 520 (2021)
Coenzyme Q10 (CoQ10) is classically viewed as an important endogenous antioxidant and key component of the mitochondrial respiratory chain. For this second function, CoQ molecules seem to be dynamically segmented in a pool attached and engulfed by th
Externí odkaz:
https://doaj.org/article/d2f2d7c4ceb944a5aeba191f41b9ec50
Autor:
Marta Luna‐Sánchez, Elena Díaz‐Casado, Emanuele Barca, Miguel Ángel Tejada, Ángeles Montilla‐García, Enrique Javier Cobos, Germaine Escames, Dario Acuña‐Castroviejo, Catarina M Quinzii, Luis Carlos López
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 5, Pp 670-687 (2015)
Abstract Primary coenzyme Q10 (CoQ10) deficiency is due to mutations in genes involved in CoQ biosynthesis. The disease has been associated with five major phenotypes, but a genotype–phenotype correlation is unclear. Here, we compare two mouse mode
Externí odkaz:
https://doaj.org/article/f4d8987aef6d405389fe3b02b95dd32d
Akademický článek
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Autor:
Pilar González-García, Marcos Martínez-Ruíz, Dario Ancuna-Castroviejo, Elena Díaz-Casado, Eliana Barriocanal-Casado, Riccardo Zenezini Chiozzi, Mohammed Bakkali, Luis C. López, Agustín Hidalgo-Gutiérrez
Background and Purpose: Recent preclinical studies have shown that β-resorcylic acid (β-RA) is an hydroxybenzoic acid derivative (HBA) potentially useful for the treatment of Coenzyme Q (CoQ) deficiencies, but the therapeutic mechanisms seem to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5dba49463a8d202f3f55a2fe83441281
https://doi.org/10.22541/au.158938611.16011582
https://doi.org/10.22541/au.158938611.16011582
