Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Elena Czink"'
Autor:
Benjamin Goeppert, Stephanie Roessler, Marcus Renner, Moritz Loeffler, Stephan Singer, Melina Rausch, Thomas Albrecht, Arianeb Mehrabi, Monika Nadja Vogel, Anita Pathil, Elena Czink, Bruno Köhler, Christoph Springfeld, Christian Rupp, Karl Heinz Weiss, Peter Schirmacher, Magnus von Knebel Doeberitz, Matthias Kloor
Publikováno v:
Diagnostic Pathology, Vol 14, Iss 1, Pp 1-6 (2019)
Abstract Background DNA mismatch repair (MMR) deficiency is a major pathway of genomic instability in cancer. It leads to the accumulation of numerous mutations predominantly at microsatellite sequences, a phenotype known as microsatellite instabilit
Externí odkaz:
https://doaj.org/article/ee0974e895414cb485f7136bb751669e
Autor:
Felix Lasitschka, Christoph Springfeld, Susanne Blank, Magnus von Knebel Doeberitz, Matthias Kloor, Georg Martin Haag, Aysel Ahadova, Elena Czink, Thomas Schmidt, Dirk Jäger, Leila Sisic, Anne Katrin Berger, Leonidas Apostolidis, Ulrike Heger
Publikováno v:
International Journal of Cancer. 144:1697-1703
Perioperative systemic treatment is standard of care for Caucasian patients with locally advanced, resectable gastric adenocarcinoma. The prognostic relevance of the microsatellite instability (MSI) status in patients undergoing neoadjuvant chemother
Autor:
Philippa Lantwin, Frederik L. Giesel, Nassim Tawanaie Pour Sedehi, Dogu Teber, Anette Duensing, Magdalena Görtz, Elena Czink, Markus Hohenfellner, Rebecca Kreuter, Carine Pecqueux, Jonas Leichsenring, Peter Schirmacher, Martina Kirchner, Tobias Simpfendörfer, Anna-Lena Volckmar, Desiree Franke, Svenja Dieffenbacher, Joanne Nyarangi-Dix, Jürgen Debus, Jan-Philipp Radtke, Maximilian Jenzer, Volker Endris, Holger Sültmann, Leonidas Apostolidis, Shirin Hoveida, Cathleen Nientiedt, Clemens Kratochwil, Claudia Gasch, Katrin Kaltenecker, Viktoria Schütz, Stefan Duensing, Georgia Christofi, Olaf Neumann, Gencay Hatiboglu, Uwe Haberkorn, Carsten Grüllich, Stefan A. Koerber, Josef Mansour, Dirk Jäger, Georgi Tosev, Gita Schönberg, Albrecht Stenzinger, Luisa Hofer, Stefanie Zschäbitz, Sanjay Isaac
Publikováno v:
Urologic oncology. 38(7)
Background Defects in DNA damage repair genes characterize a subset of men with prostate cancer and provide an attractive opportunity for precision oncology approaches. The prevalence of such perturbations in newly diagnosed, treatment-naive patients
Autor:
Benedikt Brors, Dirk Jäger, Peter Schemmer, Hanno Glimm, Christoph Heining, Peter Schirmacher, Elena Czink, Stefan Fröhling, Karl-Heinz Weiss, Felix Lasitschka, Wilko Weichert, Tim Frederik Weber, Christoph Springfeld
Publikováno v:
Zeitschrift für Gastroenterologie. 54:426-430
Gallbladder cancer represents a rare but dismal disease. The only curative option is complete surgical resection, though patients often develop recurrent disease. In patients with advanced biliary tract cancer, the combination of cisplatin and gemcit
Autor:
Magnus von Knebel Doeberitz, Anita Pathil, Karl Heinz Weiss, Christoph Springfeld, Stephan Singer, Christian Rupp, Marcus Renner, Benjamin Goeppert, Bruno Köhler, Stephanie Roessler, Peter Schirmacher, Matthias Kloor, Arianeb Mehrabi, Elena Czink, Monika Nadja Vogel, Jan Pfeiffenberger
Publikováno v:
British Journal of Cancer
Background A major molecular pathway of genetic instability in cancer is DNA mismatch repair deficiency. High-level microsatellite instability (MSI-H) is currently the best predictor of responsiveness towards immune checkpoint blockade. Data about th
Autor:
Dirk Jäger, Elena Czink, Jörn Meinel, Christoph Springfeld, Sebastian Uhrig, Karl Heinz Weiss, Christian Sutter, Benjamin Goeppert, Peter Schirmacher, Matthias Kloor, Magnus von Knebel Doeberitz, Tim Frederik Weber, Stefan Fröhling
Publikováno v:
Cold Spring Harbor Molecular Case Studies
Cancers acquire multiple somatic mutations that can lead to the generation of immunogenic mutation-induced neoantigens. These neoantigens can be recognized by the host's immune system. However, continuous stimulation of immune cells against tumor ant
Publikováno v:
Breast Care. 7:236-239
Summary Background: MRI has been demonstrated to be the most sensitive imaging method for detecting breast cancer in women at high risk, allowing depiction of cancers that are occult on mammography, ultrasound and clinical breast examination. This hi
Autor:
Christof Sohn, Geraldine Rauch, Maria Blumenstein, Joerg Heil, Kathrin Breitkreuz, Elena Czink, Joachim Rom, Julia Dahlkamp, Florian Schuetz, Michael Golatta
Publikováno v:
Annals of Surgical Oncology. 19:541-547
Reexcision is a clinically relevant aspect of oncological breast conservation surgery. The influence of reexcision on aesthetic outcome is described differently in the literature. Our aim was to analyze this question in a well-defined cohort with sta
Autor:
E. Jenetzky, Holger Hof, Sarah Schott, Geraldine Rauch, A. Maleika, Christof Sohn, Elena Czink, Michael Golatta, Maria Blumenstein, Jörg Heil
Publikováno v:
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. 37(2)
Purpose We analyzed changes in aesthetic and functional outcome over time after breast conserving therapy. Our special interest resides in the question of whether these aspects gain or loose their influence on quality of life (QoL) with temporal prog
Publikováno v:
Senologie - Zeitschrift für Mammadiagnostik und -therapie. 7