Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Elena Cressina"'
Publikováno v:
Biochemical Society Transactions. 39:652-657
Riboswitches are regions of mRNA to which a metabolite binds in the absence of proteins, resoulting in alteration of transcription, translation or splicing. The most widespread forms of riboswitches are those responsive to TPP (thiamine pyrophosphate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b307d971cac7464f1cacae65bd7ed0ed
https://doi.org/10.1042/bst0390652
https://doi.org/10.1042/bst0390652
Publikováno v:
Chem. Sci.. 2:157-165
Riboswitches are regions of mRNA that bind selectively certain metabolites, thereby regulating gene expression. We have developed a method, which uses a combination of biophysical techniques (equilibrium dialysis, waterLOGSY and T2 relaxation-edited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ede049a37aff19a7414a3988ab3a050b
https://doi.org/10.1039/c0sc00406e
https://doi.org/10.1039/c0sc00406e
Autor:
Gianfranco De Pascale, David I. Roper, Adrian J. Lloyd, Elena Cressina, Timothy D. H. Bugg, Christopher G. Dowson
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:4654-4656
Adenosine and 2′-deoxyadenosine phosphonate transition state analogues act as the first inhibitors for the MurMN/FemABX family of tRNA-dependent ligases implicated in high-level penicillin resistance in Gram-positive bacteria.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e7dfc0f16a12afd22c924bb2863e54
https://doi.org/10.1016/j.bmcl.2007.05.071
https://doi.org/10.1016/j.bmcl.2007.05.071
Publikováno v:
ACS chemical biology. 5(4)
Riboswitches are regions of mRNA that directly bind metabolites, leading to alteration of gene expression. We have developed fragment-based methods to screen for compounds that bind the Escherichia coli thiM riboswitch. Using complementary biophysica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a83b8825d7b75b64444b0c2ff7dfb204
https://pubmed.ncbi.nlm.nih.gov/20158266
https://pubmed.ncbi.nlm.nih.gov/20158266
Autor:
Elena Cressina, Timothy D. H. Bugg, B. James Mok, David I. Roper, Christopher G. Dowson, Gianfranco De Pascale, Adrian J. Lloyd, Stephen Caddick
Publikováno v:
Bioorganicmedicinal chemistry. 17(9)
Ligase MurM catalyses the addition of Ala from alanyl-tRNA(Ala), or Ser from seryl-tRNA(Ser), to lipid intermediate II in peptidoglycan biosynthesis in Streptococcus pneumoniae, and is a determinant of high-level penicillin resistance. Phosphorus-bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73a7939cf77c3798ce747f53a6dcbd85
https://pubmed.ncbi.nlm.nih.gov/19356937
https://pubmed.ncbi.nlm.nih.gov/19356937
Autor:
Paolo Tecilla, Irene Izzo, Elena Cressina, Francesco De Riccardis, Elvira Avallone, Massimo Fregonese
The synthesis of five steroid-oligo(ethyleneglycol) conjugates ( 1 – 5 ) has been accomplished starting from commercially available epi -androsterone ( 8 ) and known 3β-[( tert -butyldiphenylsilyl)oxy]-5α-23,24-bisnorchol-16-en-6α,7β,22-triol (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d898513743b5a7b3feb739244ef4d9b
http://hdl.handle.net/11386/1058613
http://hdl.handle.net/11386/1058613
Autor:
Finian J. Leeper, Elena Cressina, Kwasi Agyei-Owusu, Alison G. Smith, Chris Abell, Karl M. Erixon, Liuhong Chen, Jason Micklefield, Neil Dixon
Publikováno v:
Organic & Biomolecular Chemistry. 10:5924
The Escherichia coli thiM riboswitch forms specific contacts with its natural ligand, thiamine pyrophosphate (TPP or thiamine diphosphate), allowing it to generate not only nanomolar binding affinity, but also a high degree of discrimination against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da298b1d33874eee96b08f1cef2c41cd
https://doi.org/10.1039/c2ob07116a
https://doi.org/10.1039/c2ob07116a
Autor:
Irene Izzo, Elena Cressina, Agostino Casapullo, Paolo Tecilla, Francesco De Riccardis, Cinzia Barbara Botta, Nakia Maulucci, Massimo Fregonese
Publikováno v:
Chemical Communications. :1354
The synthesis of a new class of amphiphilic calix[ 4] arene-based ionophores, relying on direct reductive amination as a key step, and the evaluation of their H+ and Na+ transporting properties is described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a17825c7bb47b38aef184140c4e3034
https://doi.org/10.1039/b415908j
https://doi.org/10.1039/b415908j
Autor:
Nakia Maulucci, Francesco De Riccardis, Cinzia Barbara Botta, Agostino Casapullo, Elena Cressina, Massimo Fregonese, Paolo Tecilla, Irene Izzo
Publikováno v:
Chemical Communications; Mar2005, Vol. 2005 Issue 10, p1354-1356, 3p