Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Elena Copreni"'
Publikováno v:
Viruses, Vol 2, Iss 8, Pp 1577-1588 (2010)
The aim of this work was to evaluate the efficiency and duration of gene expression mediated by a VSV-G pseudotyped last generation lentiviral (LV) vector. We studied LV efficiency in ex-vivo models of respiratory epithelial cells, obtained from bron
Externí odkaz:
https://doaj.org/article/d09dde17f1e54549859fd68869218857
Autor:
Valter Torri, R. Labianca, Elena Copreni, Calogero Lauricella, M.C. Garassino, Eliana Rulli, Silvio Veronese, Flavia Longo, Mirko Marabese, Anna Cecilia Bettini, Gabriella Farina, Monica Ganzinelli, Olga Martelli, Massimo Broggini, Luca Moscetti, Silvia Marsoni
Publikováno v:
Annals of Oncology. 26:2079-2084
Background The prognostic and predictive role of KRAS mutations in advanced nonsmall-cell lung cancer (NSCLC) is still unclear. TAILOR prospectively assessed the prognostic and predictive value of KRAS mutations in NSCLC patients treated with erlotin
Autor:
Stefano Castellani, Pieter S. Hiemstra, Anna Diana, Pascal van der Wegen, Francesca Tilesi, Guelnihal Yueksekdag, Joseph Rosenecker, Jamil Aarbiou, Bob J. Scholte, Ruvalic M. Buijs-Offerman, Elena Copreni, Fiorentina Ascenzioni, Piera Assunta Fradiani, Annalucia Carbone, Massimo Conese
Publikováno v:
The Journal of Gene Medicine. 14:733-745
BACKGROUND Epithelial sodium channel (ENaC) hyperactivity has been implicated in the pathogenesis of cystic fibrosis (CF) by dysregulation of fluid and electrolytes in the airways. In the present study, we show proof-of-principle for ENaC inhibition
Autor:
Elena Copreni, Maria Grazia Giri, Lucia Palmieri, Antonio Vella, Giulio Cabrini, Marco Colombatti, Elena Nicolis, Paolo Rizzotti, Massimo Conese, Valentino Bezzerri, Stefano Castellani, Anna Tamanini
Publikováno v:
Università degli studi di Foggia-IRIS
Lentiviruses (LVs) are considered one of the most promising tools for gene transfer, however, their potential to induce pro-inflammatory cytokines on delivery into the respiratory tissue remains to be established. Here we tested a third-generation ve
Autor:
Roberto Labianca, Ida Pavese, Elena Copreni, Claudia Bareggi, Elisa Caiola, Alessandro Bertolini, M.G. Sarobba, Flavia Longo, Maria Cristina Locatelli, Mirko Marabese, Giuseppe Valmadre, Daniele Fagnani, Marina Chiara Garassino, Monica Ganzinelli, Massimo Broggini, Eliana Rulli, Anna Calcagno, Maria Agnese Fabbri, Sheila Piva, Olga Martelli
Publikováno v:
Scientific Reports
MicroRNAs were described to target mRNA and regulate the transcription of genes involved in processes de-regulated in tumorigenesis, such as proliferation, differentiation and survival. In particular, the miRNA let-7 has been suggested to regulate th
Autor:
Giliola Calori, Alessia Rocchi, Diana Costantini, M.L. Garlaschi, Carla Colombo, Lisa Cariani, Silvia Amedea Tirelli, Massimo Conese, Elena Copreni
Publikováno v:
Pediatric Pulmonology. 40:15-21
It is not known whether cytokine levels in sputum may be used as outcome measures after parenteral antibiotic therapy in cystic fibrosis (CF) patients. Here, we assessed the effects of antibiotic therapy on cytokine levels in sputum and serum obtaine
Autor:
Jamil, Aarbiou, Elena, Copreni, Ruvalic M, Buijs-Offerman, Pascal, van der Wegen, Stefano, Castellani, Annalucia, Carbone, Francesca, Tilesi, Piera, Fradiani, Pieter S, Hiemstra, Guelnihal, Yueksekdag, Anna, Diana, Joseph, Rosenecker, Fiorentina, Ascenzioni, Massimo, Conese, Bob J, Scholte
Publikováno v:
The journal of gene medicine. 14(12)
Epithelial sodium channel (ENaC) hyperactivity has been implicated in the pathogenesis of cystic fibrosis (CF) by dysregulation of fluid and electrolytes in the airways. In the present study, we show proof-of-principle for ENaC inhibition by lentivir
Autor:
Elena, Copreni, Stefano, Castellani, Annalisa, Bagnacani, Augusto, Colombo, Tommaso, Rizzuti, Sante, Di Gioia, Carla, Colombo, Massimo, Conese
Publikováno v:
Medical science monitor : international medical journal of experimental and clinical research. 16(12)
Pseudomonas aeruginosa is an opportunistic pathogen that causes chronic endobronchial infections in cystic fibrosis (CF) patients. The role of bacterial internalization in the clearance of P. aeruginosa from the airways is controversial.A xenograft m
Autor:
Massimo Conese, Elena Copreni, Christian Plank, Stefano Castellani, Olivier Zelphati, Olga Mykhaylyk, Clara Orlando
Publikováno v:
Università degli studi di Foggia-IRIS
Lentiviral (LV) vectors are able to only slowly and inefficiently transduce nondividing cells such as those of the airway epithelium. To address this issue, we have exploited the magnetofection technique in in vitro models of airway epithelium.Magnet
Autor:
Diana Costantini, Elena Copreni, Alessandra Livraghi, Carla Colombo, Salvatore Carrabino, Daniela Carpani, Maurizio Di Cicco, Massimo Conese
Publikováno v:
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 5(2)
Background It is not clear whether cystic fibrosis (CF) airway inflammation is a consequence of bacterial infection or is intrinsically dysregulated. The aim of this study was to investigate IL-8 secretion and NF-κB activity in primary respiratory e