Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Elena Cardenal‐Muñoz"'
Autor:
Sandra Solaz, Elena Cardenal‐Muñoz, Alicia Muñoz, Simona Giorgi, Federico V. Pallardó, Carlos Romá‐Mateo, José Ángel Aibar
Publikováno v:
Epilepsia Open, Vol 9, Iss 5, Pp 1806-1815 (2024)
Abstract Objectives Dravet syndrome (DS) is a rare form of refractory epilepsy that begins in the first year of life. Approximately 85% of patients have a mutation in the SCN1A gene, which encodes a voltage‐gated sodium channel. The main objective
Externí odkaz:
https://doaj.org/article/c543f2f3de9046249ef6489227c98ab3
Autor:
Anat Mavashov, Marina Brusel, Jiaxing Liu, Victoria Woytowicz, Haneui Bae, Ying-Hsin Chen, Vardhan S. Dani, Elena Cardenal-Muñoz, Vittoria Spinosa, José Ángel Aibar, Moran Rubinstein
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Dravet syndrome (Dravet) is a severe congenital developmental genetic epilepsy caused by de novo mutations in the SCN1A gene. Nonsense mutations are found in ∼20% of the patients, and the R613X mutation was identified in multiple patients. Here we
Externí odkaz:
https://doaj.org/article/a514e71d032547999588604f107d69b1
Autor:
Elena Cardenal‐Muñoz, Stéphane Auvin, Vicente Villanueva, J. Helen Cross, Sameer M. Zuberi, Lieven Lagae, José Ángel Aibar
Publikováno v:
Epilepsia Open, Vol 7, Iss 1, Pp 11-26 (2022)
Abstract Dravet syndrome (DS) is a severe, rare, and complex developmental and epileptic encephalopathy affecting 1 in 16 000 live births and characterized by a drug‐resistant epilepsy, cognitive, psychomotor, and language impairment, and behaviora
Externí odkaz:
https://doaj.org/article/6f738f3396a94d8e9441daf564c14571
Autor:
Isabella Brambilla, José Ángel Aibar, Anne Sophie Hallet, Irena Bibic, Elena Cardenal‐Muñoz, Igor Prpic, Francesca Darra, Nicola Specchio, Rima Nabbout
Publikováno v:
Epilepsia Open, Vol 6, Iss 1, Pp 216-224 (2021)
Abstract We explored the impact of coronavirus virus 2019 (COVID‐19) pandemic on patients with Dravet syndrome (DS) and their family. With European patient advocacy groups (PAGs), we developed an online survey in 10 languages to question health sta
Externí odkaz:
https://doaj.org/article/9a230068502c43e4ac1d353b0195639c
Autor:
Nabil Hanna, Hendrik Koliwer-Brandl, Louise H. Lefrançois, Vera Kalinina, Elena Cardenal-Muñoz, Joddy Appiah, Florence Leuba, Aurélie Gueho, Hubert Hilbi, Thierry Soldati, Caroline Barisch
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
Microelements are essential for the function of the innate immune system. A deficiency in zinc or copper results in an increased susceptibility to bacterial infections.
Externí odkaz:
https://doaj.org/article/39a95568039a4b7dacf1f43313be79d2
Autor:
Ana T López-Jiménez, Elena Cardenal-Muñoz, Florence Leuba, Lilli Gerstenmaier, Caroline Barisch, Monica Hagedorn, Jason S King, Thierry Soldati
Publikováno v:
PLoS Pathogens, Vol 14, Iss 12, p e1007501 (2018)
Phagocytic cells capture and kill most invader microbes within the bactericidal phagosome, but some pathogens subvert killing by damaging the compartment and escaping to the cytosol. To prevent the leakage of pathogen virulence and host defence facto
Externí odkaz:
https://doaj.org/article/38e2e813fd284008adff457f66458ec9
Autor:
Elena Cardenal-Muñoz, Caroline Barisch, Louise H. Lefrançois, Ana T. López-Jiménez, Thierry Soldati
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 7 (2018)
In recent years, Dictyostelium discoideum has become an important model organism to study the cell biology of professional phagocytes. This amoeba not only shares many molecular features with mammalian macrophages, but most of its fundamental signal
Externí odkaz:
https://doaj.org/article/8b40547b89a2473d9adfe47391d0dd28
Autor:
Joe Dan Dunn, Cristina Bosmani, Caroline Barisch, Lyudmil Raykov, Louise H. Lefrançois, Elena Cardenal-Muñoz, Ana Teresa López-Jiménez, Thierry Soldati
Publikováno v:
Frontiers in Immunology, Vol 8 (2018)
The soil-dwelling social amoeba Dictyostelium discoideum feeds on bacteria. Each meal is a potential infection because some bacteria have evolved mechanisms to resist predation. To survive such a hostile environment, D. discoideum has in turn evolved
Externí odkaz:
https://doaj.org/article/dc4aa45fafd14300a876553f4863c16c
Autor:
Elena Cardenal-Muñoz, Sonia Arafah, Ana Teresa López-Jiménez, Sébastien Kicka, Alexandra Falaise, Frauke Bach, Olivier Schaad, Jason S King, Monica Hagedorn, Thierry Soldati
Publikováno v:
PLoS Pathogens, Vol 13, Iss 4, p e1006344 (2017)
Autophagy is a eukaryotic catabolic process also participating in cell-autonomous defence. Infected host cells generate double-membrane autophagosomes that mature in autolysosomes to engulf, kill and digest cytoplasmic pathogens. However, several bac
Externí odkaz:
https://doaj.org/article/912a7fe7edb641a1b06bf0363c3ab118
Publikováno v:
The International Journal of Developmental Biology. 63:317-320
When we set out to organize this Special Issue, we faced the difficult task of gathering together a large variety of topics with the unique commonality of having been studied in a single model organism, Dictyostelium discoideum. This apparent setback
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce4fcc3f4b75907fbe7e13a048cd105a
https://doi.org/10.1387/ijdb.190275re
https://doi.org/10.1387/ijdb.190275re