Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Elena Capparelli"'
Publikováno v:
Clinical Epidemiology and Global Health, Vol 28, Iss , Pp 101658- (2024)
Background: Antibiotic resistance (AR) represents a global health challenge. Within the coordinated efforts to tackle AR, community education is a key strategy to enhance awareness and improve antibiotic use. The current study intends to investigate
Externí odkaz:
https://doaj.org/article/60bcdd43a1434d1a94adf14708bbac1c
Autor:
Angela Altomare, Elena Capparelli, Antonio Carrieri, Nicola A. Colabufo, Anna Moliterni, Rosanna Rizzi, Dritan Siliqi
Publikováno v:
Acta Crystallographica Section E, Vol 70, Iss 11, Pp o1149-o1150 (2014)
The title compound, C24H25NO3·2CH3OH, which crystallized as a methanol disolvate, has applications as a PET radiotracer in the early diagnosis of Alzheimer's disease. The dihedral angle between the biphenyl rings is 8.2 (2)° and the heterocyclic ri
Externí odkaz:
https://doaj.org/article/611afdd432be411c9b457cd5e5d39035
Publikováno v:
Universal Journal of Public Health. 11:185-204
Publikováno v:
Acta Pharmaceutica Sciencia. 59:533-547
Autor:
Carmen Abate, Nicola Antonio Colabufo, Elena Capparelli, Marialessandra Contino, Francesco Spinelli
Publikováno v:
Journal of Medicinal Chemistry. 60:9913-9931
Up-regulation of CB2R on activated microglial cells, the first step in neurodegeneration, has been widely demonstrated, and this finding makes the receptor a promising target in the early diagnosis and treatment of several neurodegenerative disorders
Autor:
Nicola Antonio Colabufo, Roberto Perrone, Elena Capparelli, Marialessandra Contino, Maria Grazia Perrone, Francesco Berardi, Marcello Leopoldo
Publikováno v:
Archiv der Pharmazie. 349:161-167
Starting from our lead compound MC70 displaying high P-glycoprotein (P-gp) inhibition activity but low selectivity, a new class of coumarine derivatives was studied to develop selective and fluorescent P-gp ligands. In this series, the biphenyl moiet
Publikováno v:
The CB2 Cannabinoid System: A New Strategy in Neurodegenerative Disorder and Neuroinflammation
Frontiers in Neuroscience
Frontiers in Neuroscience
Autor:
Elena Capparelli, Nicola Antonio Colabufo, Francesco Berardi, Maria Grazia Perrone, Marialessandra Contino, Gert Luurtsema, Laura Zinzi, Mariangela Cantore, Roberto Perrone
Publikováno v:
Journal of Medicinal Chemistry, 57(23), 9983-9994. AMER CHEMICAL SOC
The development of P-glycoprotein (P-gp) ligands remains of considerable interest, mostly for investigating the protein's structure and transport mechanism. In recent years, many different generations of ligands have been tested for their ability to
Autor:
Elena Capparelli, Severin Mairinger, Claudia Kuntner, Yaprak Doenmez, Markus Müller, Sabine Strommer, Thomas Wanek, Nicola Antonio Colabufo, Oliver Langer, Peter Chiba, Johann Stanek
Publikováno v:
Nuclear Medicine and Biology; Vol 39
Nuclear Medicine and Biology
Nuclear Medicine and Biology
With the aim to develop a PET tracer to visualize P-glycoprotein (Pgp) expression levels in different organs, the Pgp inhibitor MC113 was labeled with (11)C and evaluated using small-animal PET.[(11)C]MC113 was synthesized by reaction of O-desmethyl
Autor:
Elena Capparelli, Francesco Berardi, Roberto Perrone, Marialessandra Contino, Carmela Inglese, Mauro Niso, Nicola Antonio Colabufo, Mariangela Cantore, Maria Grazia Perrone, Marcello Leopoldo
Publikováno v:
ChemMedChem. 7:391-395