The multispecies microbial cluster of Fusobacterium, Parvimonas, Bacteroides and Faecalibacterium as a precision biomarker for colorectal cancer diagnosis

Autor: Kelly Conde‐Pérez, Pablo Aja‐Macaya, Elena Buetas, Noelia Trigo‐Tasende, Mohammed Nasser‐Ali, Soraya Rumbo‐Feal, Paula Nión, Elsa Martín‐De Arribas, Lara S. Estévez, Begoña Otero‐Alén, José F. Noguera, Ángel Concha, Simón Pardiñas‐López, Miguel Carda‐Diéguez, Igor Gómez‐Randulfe, Nieves Martínez‐Lago, Susana Ladra, Luis M. A. Aparicio, Germán Bou, Álex Mira, Juan A. Vallejo, Margarita Poza

Publikováno v: Molecular Oncology, Vol 18, Iss 5, Pp 1093-1122 (2024)

The incidence of colorectal cancer (CRC) has increased worldwide, and early diagnosis is crucial to reduce mortality rates. Therefore, new noninvasive biomarkers for CRC are required. Recent studies have revealed an imbalance in the oral and gut micr

Externí odkaz: https://doaj.org/article/b1bf2e9928fb424aad8f430b52eb7a0a

Full-length 16S rRNA gene sequencing by PacBio improves taxonomic resolution in human microbiome samples

Autor: Elena Buetas, Marta Jordán-López, Andrés López-Roldán, Giuseppe D’Auria, Llucia Martínez-Priego, Griselda De Marco, Miguel Carda-Diéguez, Alex Mira

Publikováno v: BMC Genomics, Vol 25, Iss 1, Pp 1-13 (2024)

Abstract Background Sequencing variable regions of the 16S rRNA gene (≃300 bp) with Illumina technology is commonly used to study the composition of human microbiota. Unfortunately, short reads are unable to differentiate between highly similar spe

Externí odkaz: https://doaj.org/article/36da24329f4941aaaf14ea07445849f6

Gravidity and malaria trends interact to modify P. falciparum densities and detectability in pregnancy: a 3-year prospective multi-site observational study

Autor: Glória Matambisso, Nanna Brokhattingen, Sónia Maculuve, Pau Cisteró, Henriques Mbeve, Anna Escoda, Judice Miguel, Elena Buetas, Ianthe de Jong, Boaventura Cuna, Cardoso Melembe, Nelo Ndimande, Gemma Porras, Haily Chen, Kevin K. A. Tetteh, Chris Drakeley, Benoit Gamain, Chetan Chitnis, Virander Chauhan, Llorenç Quintó, Beatriz Galatas, Eusébio Macete, Alfredo Mayor

Publikováno v: BMC Medicine, Vol 20, Iss 1, Pp 1-12 (2022)

Abstract Background Low-density Plasmodium falciparum infections prevail in low transmission settings, where immunity is expected to be minimal, suggesting an immune-independent effect on parasite densities. We aimed to describe parasite densities in

Externí odkaz: https://doaj.org/article/8482e32ae99a4b09a14169cc03cfcd21

Evidence for translocation of oral Parvimonas micra from the subgingival sulcus of the human oral cavity to the colorectal adenocarcinoma

Autor: Kelly Conde-Pérez, Elena Buetas, Pablo Aja-Macaya, Elsa Martín-De Arribas, Iago Iglesias-Corrás, Noelia Trigo-Tasende, Mohammed Nasser-Ali, Lara S. Estévez, Soraya Rumbo-Feal, Begoña Otero-Alén, José F. Noguera, Ángel Concha, Simón Pardiñas-López, Miguel Carda-Diéguez, Igor Gómez-Randulfe, Nieves Martínez-Lago, Susana Ladra, Luis M. A. Aparicio, Germán Bou, Álex Mira, Juan A. Vallejo, Margarita Poza

Background: The carcinogenesis of colorectal cancer (CRC) is a multifactorial process involving both environmental and host factors, such as human genetics or the gut microbiome, which in CRC patients appears to be enriched in oral microorganisms. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8aa37543954af9e760795a9ea7e8837c
https://doi.org/10.21203/rs.3.rs-2096158/v1

Development of an in vitro system to study oral biofilms in real time through impedance technology: validation and potential applications

Autor: María D. Ferrer, Carmen Llena, Bob T. Rosier, Danuta Mazurel, Álvaro Villanueva-Castellote, Elena Buetas, Alex Mira

Publikováno v: Journal of Oral Microbiology
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
r-FISABIO. Repositorio Institucional de Producción Científica
instname
Journal of Oral Microbiology, Vol 11, Iss 1 (2019)

Background and objectives: We have developed a standardized, easy-to-use in vitro model to study single- and multiple-species oral biofilms in real time through impedance technology, which elucidates the kinetics of biofilm formation in 96-well plate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6f4debac88c261d1b1cddb469653137
https://doi.org/10.1080/20002297.2019.1609838