Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Elena Britan"'
Autor:
Alexander Botvinnik, Elena Britan-Rosich, Udy Olshevsky, Harold Oliva, Núria Climent, Yoav Smith, Ofra Moshel, Moshe Kotler, Zakhariya Manevitch, Pushkar Shivam, Gunjan Sharma
Publikováno v:
The FEBS Journal. 288:6063-6077
Human apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G (hA3G), a member of the APOBEC family, was described as an anti-HIV-1 restriction factor, deaminating reverse transcripts of the HIV-1 genome. Several types of cancer cells tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b89c6ff33a976049509881d729bfaf3
https://doi.org/10.1111/febs.16025
https://doi.org/10.1111/febs.16025
Autor:
Moshe Kotler, Pushkar Shivam, Udy Olshevsky, Yoav Smith, Ofra Moshel, Zakhariya Manevitch, Alexander Botvinnik, Gunjan Sharma, Harold Oliva, Núria Climent, Elena Britan-Rosich
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af7557d4a1a4c878a22df6d196e76d61
https://doi.org/10.1111/febs.16025/v3/response1
https://doi.org/10.1111/febs.16025/v3/response1
Publikováno v:
Journal of Molecular Biology. 426:2840-2853
Deamination of cytidine residues in viral DNA is a major mechanism by which APOBEC3G (A3G) inhibits vif-deficient human immunodeficiency virus type 1 (HIV-1) replication. dC-to-dU transition following RNase-H activity leads to viral cDNA degradation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4976b146ab838d0c54492be51fdba5f
https://doi.org/10.1016/j.jmb.2014.05.012
https://doi.org/10.1016/j.jmb.2014.05.012
Autor:
Moshe Kotler, Meytal Galilee, Elena Britan-Rosich, Akram Alian, Don C. Lamb, Robert M. Stroud, Anthony A. Kossiakoff, Serdar Uysal, Viola Baumgärtel, Sarah L. Griner, Ailie Marx
HIV-1 integrase (IN) catalyzes viral DNA integration into the host genome and facilitates multifunctional steps including virus particle maturation. Competency of IN to form multimeric assemblies is functionally critical, presenting an approach for a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f337693bbf0f824149a69743288c5acf
https://openaccess.bezmialem.edu.tr/handle/20.500.12645/13453
https://openaccess.bezmialem.edu.tr/handle/20.500.12645/13453
APOBEC3G enhances lymphoma cell radioresistance by promoting cytidine deaminase-dependent DNA repair
Autor:
Michal Goldberg, Arnon Nagler, Reuben S. Harris, Ori Cheshin, Leah Baraz, Ofer I. Wilner, Moshe Kotler, Itamar Willner, Elena Britan-Rosich, Roni Nowarski, Or David Shahar, Edan Kenig
Publikováno v:
Blood. 120:366-375
APOBEC3 proteins catalyze deamination of cytidines in single-stranded DNA (ssDNA), providing innate protection against retroviral replication by inducing deleterious dC > dU hypermutation of replication intermediates. APOBEC3G expression is induced i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4507c68117ebd57b692c260b720c77f3
https://doi.org/10.1182/blood-2012-01-402123
https://doi.org/10.1182/blood-2012-01-402123
Autor:
Joseph Rosenbluh, Elena Britan, Moshe Kotler, Zvi Hayouka, Amnon Hizi, Aviad Levin, Ayelet Armon-Omer, Assaf Friedler, Abraham Loyter, Shoshana Loya
Publikováno v:
Journal of Biological Chemistry. 282:15743-15753
Human immunodeficiency virus 1 (HIV-1) Rev and integrase (IN) proteins are required within the nuclei of infected cells in the late and early phases of the viral replication cycle, respectively. Here we show using various biochemical methods, that th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d2a109cd55f3646eafec715b96eabfe
https://doi.org/10.1074/jbc.m609864200
https://doi.org/10.1074/jbc.m609864200
Autor:
Moshe Kotler, Elena Britan-Rosich, Shivender M.D. Shandilya, Celia A. Schiffer, Ponnandy Prabhu, Adi Nagler
Publikováno v:
The FEBS journal. 283(1)
The cellular cytidine deaminase APOBEC3G (A3G) was first described as an anti-HIV-1 restriction factor, acting by directly deaminating reverse transcripts of the viral genome. HIV-1 Vif neutralizes the activity of A3G, primarily by mediating degradat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac780e15f8d2710f8dc93f1463d54cbf
https://pubmed.ncbi.nlm.nih.gov/26460502
https://pubmed.ncbi.nlm.nih.gov/26460502
Autor:
Immanuel Blumenzweig, Michael Steinitz, Moshe Kotler, Elena Britan, Lea Baraz, Marina Hutoran
Publikováno v:
Virology. 330(1):261-270
The human immunodeficiency virus type 1 (HIV-1) auxiliary gene vif is essential for virus propagation in peripheral blood lymphocytes, macrophages, and in some T-cell lines. Previously, it was demonstrated that Vif inhibits the autoprocessing of trun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0f94b7873d639f5d313f2cf787fdfb2
Autor:
Elena Britan-Rosich, Shahar Rotem-Bamberger, Robert Blumenthal, Jeeseong Hwang, Moshe Kotler, Assaf Friedler, Ji Youn Lee, Amy Jacobs, Mathias Viard, Abigail E Miller, Tali H. Reingewertz
Publikováno v:
Bioorganicmedicinal chemistry. 21(12)
Human apolipoprotein-B mRNA-editing catalytic polypeptide-like 3G (A3G) is a cytidine deaminase that restricts retroviruses, endogenous retro-elements and DNA viruses. A3G plays a key role in the anti-HIV-1 innate cellular immunity. The HIV-1 Vif pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5816350a22f6944df31417208ddec4b
https://pubmed.ncbi.nlm.nih.gov/23545135
https://pubmed.ncbi.nlm.nih.gov/23545135
Publikováno v:
Journal of molecular biology. 410(5)
In the absence of human immunodeficiency virus type 1 (HIV-1) Vif protein, the host antiviral deaminase apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like 3G (A3G) restricts the production of infectious HIV-1 by deamination of dC residue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e64bf55dafdb01947cd97b37d3890feb
https://pubmed.ncbi.nlm.nih.gov/21763507
https://pubmed.ncbi.nlm.nih.gov/21763507