Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Elena Bonora"'
Autor:
Isotta Bozzarelli, Arianna Orsini, Federica Isidori, Luca Mastracci, Deborah Malvi, Marialuisa Lugaresi, Silvia Fittipaldi, Livia Gozzellino, Annalisa Astolfi, Jari Räsänen, Antonia D’Errico, Riccardo Rosati, Roberto Fiocca, Marco Seri, Kausilia K. Krishnadath, Elena Bonora, Sandro Mattioli
Publikováno v:
Cancers, Vol 16, Iss 3, p 591 (2024)
Alterations in microRNA (miRNA) expression have been reported in different cancers. We assessed the expression of 754 oncology–related miRNAs in esophageal adenocarcinoma (EAC) samples and evaluated their correlations with clinical parameters. We f
Externí odkaz:
https://doaj.org/article/f497ea7254dc42cabc7bc5e407139d43
Mutant SPART causes defects in mitochondrial protein import and bioenergetics reversed by Coenzyme Q
Autor:
Chiara Diquigiovanni, Nicola Rizzardi, Antje Kampmeier, Irene Liparulo, Francesca Bianco, Bianca De Nicolo, Erica Cataldi-Stagetti, Elisabetta Cuna, Giulia Severi, Marco Seri, Miriam Bertrand, Tobias B. Haack, Adela Della Marina, Frederik Braun, Romana Fato, Alma Kuechler, Christian Bergamini, Elena Bonora
Publikováno v:
Open Biology, Vol 13, Iss 7 (2023)
Pathogenic variants in SPART cause Troyer syndrome, characterized by lower extremity spasticity and weakness, short stature and cognitive impairment, and a severe mitochondrial impairment. Herein, we report the identification of a role of Spartin in
Externí odkaz:
https://doaj.org/article/3a2f4d216a754efba99fc06b6d4bfab0
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/057807f5f09f4d95bbec1894044b6223
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12690 (2023)
Breast cancer (BC) has yielded approximately 2.26 million new cases and has caused nearly 685,000 deaths worldwide in the last two years, making it the most common diagnosed cancer type in the world. BC is an intricate ecosystem formed by both the tu
Externí odkaz:
https://doaj.org/article/f29aa9ccb7f4440ba21a37ec1d44e499
Autor:
Diego Quattrone, Ulrich Reininghaus, Alex L. Richards, Giada Tripoli, Laura Ferraro, Andrea Quattrone, Paolo Marino, Victoria Rodriguez, Edoardo Spinazzola, Charlotte Gayer-Anderson, Hannah E. Jongsma, Peter B. Jones, Caterina La Cascia, Daniele La Barbera, Ilaria Tarricone, Elena Bonora, Sarah Tosato, Antonio Lasalvia, Andrei Szöke, Celso Arango, Miquel Bernardo, Julio Bobes, Cristina Marta Del Ben, Paulo Rossi Menezes, Pierre-Michel Llorca, Jose Luis Santos, Julio Sanjuán, Manuel Arrojo, Andrea Tortelli, Eva Velthorst, Steven Berendsen, Lieuwe de Haan, Bart P. F. Rutten, Michael T. Lynskey, Tom P. Freeman, James B. Kirkbride, Pak C. Sham, Michael C. O’Donovan, Alastair G. Cardno, Evangelos Vassos, Jim van Os, Craig Morgan, Robin M. Murray, Cathryn M. Lewis, Marta Di Forti, EU-GEI collaborators
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Diagnostic categories do not completely reflect the heterogeneous expression of psychosis. Using data from the EU-GEI study, we evaluated the impact of schizophrenia polygenic risk score (SZ-PRS) and patterns of cannabis use on the transdiag
Externí odkaz:
https://doaj.org/article/6cbca552cb464ee398caf31d979f1866
Autor:
Anna Ferrari, Roberto Fiocca, Elena Bonora, Chiara Domizio, Eugenio Fonzi, Davide Angeli, Gian Domenico Raulli, Sandro Mattioli, Giovanni Martinelli, Chiara Molinari
Publikováno v:
Genes, Vol 14, Iss 4, p 918 (2023)
Adenocarcinoma of the esophagus (EAC) and gastroesophageal junction (GEJ-AC) is associated with poor prognosis, treatment resistance and limited systemic therapeutic options. To deeply understand the genomic landscape of this cancer type, and potenti
Externí odkaz:
https://doaj.org/article/9c8e3f85a77a47288abf63505751e0ea
Autor:
Arianna Orsini, Luca Mastracci, Isotta Bozzarelli, Anna Ferrari, Federica Isidori, Roberto Fiocca, Marialuisa Lugaresi, Antonietta D’Errico, Deborah Malvi, Erica Cataldi-Stagetti, Paola Spaggiari, Anna Tomezzoli, Luca Albarello, Ari Ristimäki, Luca Bottiglieri, Kausilia K. Krishnadath, Riccardo Rosati, Uberto Fumagalli Romario, Giovanni De Manzoni, Jari Räsänen, Giovanni Martinelli, Sandro Mattioli, Elena Bonora, on behalf of the EACSGE Consortium
Publikováno v:
Cancers, Vol 15, Iss 5, p 1408 (2023)
Esophageal adenocarcinoma (EAC) is a severe malignancy with increasing incidence, poorly understood pathogenesis, and low survival rates. We sequenced 164 EAC samples of naïve patients (without chemo-radiotherapy) with high coverage using next-gener
Externí odkaz:
https://doaj.org/article/c5d63308601143ff8cf0dec7fc752e83
Publikováno v:
Antioxidants, Vol 12, Iss 2, p 353 (2023)
Mitochondria are key players in energy production, critical activity for the smooth functioning of energy-demanding organs such as the muscles, brain, and heart. Therefore, dysregulation or alterations in mitochondrial bioenergetics primarily perturb
Externí odkaz:
https://doaj.org/article/81764406cc8f4bb39e110d2f2a4c4d10
Autor:
Francesca Bianco, Giulia Lattanzio, Luca Lorenzini, Maurizio Mazzoni, Paolo Clavenzani, Laura Calzà, Luciana Giardino, Catia Sternini, Anna Costanzini, Elena Bonora, Roberto De Giorgio
Publikováno v:
Biomolecules, Vol 12, Iss 12, p 1849 (2022)
Severe gut motility disorders are characterized by the ineffective propulsion of intestinal contents. As a result, the patients develop disabling/distressful symptoms, such as nausea and vomiting along with altered bowel habits up to radiologically d
Externí odkaz:
https://doaj.org/article/89c93a2285614ca999f98c17887b6fb1
Autor:
Francesca Bianco, Giulia Lattanzio, Luca Lorenzini, Chiara Diquigiovanni, Maurizio Mazzoni, Paolo Clavenzani, Laura Calzà, Luciana Giardino, Catia Sternini, Elena Bonora, Roberto De Giorgio
Publikováno v:
European Journal of Histochemistry, Vol 65, Iss s1 (2021)
The enteric nervous system (ENS) is the third division of the autonomic autonomic nervous system and the largest collection of neurons outside the central nervous system (CNS). The ENS has been referred to as “the brain in the gut” or “the seco
Externí odkaz:
https://doaj.org/article/38cb5a1f156c41da91e4e1b8dee00e58