Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Elena Bernabeu"'
Autor:
Danni A. Gadd, Hannah M. Smith, Donncha Mullin, Ola Chybowska, Robert F. Hillary, Dorien M. Kimenai, Elena Bernabeu, Yipeng Cheng, Chloe Fawns-Ritchie, Archie Campbell, Danielle Page, Adele Taylor, Janie Corley, Maria Del C. Valdés-Hernández, Susana Muñoz Maniega, Mark E. Bastin, Joanna M. Wardlaw, Rosie M. Walker, Kathryn L. Evans, Andrew M. McIntosh, Caroline Hayward, Tom C. Russ, Sarah E. Harris, Paul Welsh, Naveed Sattar, Simon R. Cox, Daniel L. McCartney, Riccardo E. Marioni
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-15 (2024)
Abstract Background Plasma growth differentiation factor 15 (GDF15) and N‐terminal proB‐type natriuretic peptide (NT‐proBNP) are cardiovascular biomarkers that associate with a range of diseases. Epigenetic scores (EpiScores) for GDF15 and NT-p
Externí odkaz:
https://doaj.org/article/76e8233ab631452ab514eb985f52d351
Autor:
Elena Bernabeu, Daniel L. McCartney, Danni A. Gadd, Robert F. Hillary, Ake T. Lu, Lee Murphy, Nicola Wrobel, Archie Campbell, Sarah E. Harris, David Liewald, Caroline Hayward, Cathie Sudlow, Simon R. Cox, Kathryn L. Evans, Steve Horvath, Andrew M. McIntosh, Matthew R. Robinson, Catalina A. Vallejos, Riccardo E. Marioni
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-15 (2023)
Abstract Background Epigenetic clocks can track both chronological age (cAge) and biological age (bAge). The latter is typically defined by physiological biomarkers and risk of adverse health outcomes, including all-cause mortality. As cohort sample
Externí odkaz:
https://doaj.org/article/11ded94b605a495a931ef5473f213f7c
Autor:
Robert F Hillary, Daniel L McCartney, Hannah M Smith, Elena Bernabeu, Danni A Gadd, Aleksandra D Chybowska, Yipeng Cheng, Lee Murphy, Nicola Wrobel, Archie Campbell, Rosie M Walker, Caroline Hayward, Kathryn L Evans, Andrew M McIntosh, Riccardo E Marioni
Publikováno v:
PLoS Medicine, Vol 20, Iss 7, p e1004247 (2023)
BackgroundDNA methylation is a dynamic epigenetic mechanism that occurs at cytosine-phosphate-guanine dinucleotide (CpG) sites. Epigenome-wide association studies (EWAS) investigate the strength of association between methylation at individual CpG si
Externí odkaz:
https://doaj.org/article/f0b1e6cceb97419e8873e65cb9b0489b
Publikováno v:
Toxics, Vol 11, Iss 8, p 716 (2023)
The escalating global anthropogenic activities associated with industrial development have led to the increased introduction of heavy metals (HMs) into marine environments through effluents. This study aimed to assess the toxicity of three HMs (Cr, C
Externí odkaz:
https://doaj.org/article/80dc75d34b204dc3b84228312c227297
Autor:
Alesha A Hatton, Robert F Hillary, Elena Bernabeu, Daniel L McCartney, Riccardo E Marioni, Allan F McRae
The recent increase in obesity levels across many countries is likely to be driven by nongenetic factors. The epigenetic modification DNA methylation (DNAm) may help to explore this as it is sensitive to both genetic and environmental exposures. Whil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fd7bfa1dd539df1900f66b8578ba7fa
https://doi.org/10.1101/2023.03.05.530890
https://doi.org/10.1101/2023.03.05.530890
Autor:
Eleanor Davyson, Xueyi Shen, Danni A. Gadd, Elena Bernabeu, Robert F. Hillary, Daniel L. McCartney, Mark Adams, Riccardo Marioni, Andrew M. McIntosh
Publikováno v:
Davyson, E, Shen, X, Gadd, D A, Bernabeu, E, Hillary, R F, McCartney, D L, Adams, M, Marioni, R & McIntosh, A M 2023, ' Metabolomic investigation of major depressive disorder identifies a potentially causal association with polyunsaturated fatty acids ', Biological Psychiatry . https://doi.org/10.1016/j.biopsych.2023.01.027
BACKGROUND: Metabolic differences have been reported between individuals with and without major depressive disorder (MDD), but their consistency and causal relevance have been unclear.METHODS: We conducted a metabolome-wide association study of MDD w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::665db2ff89d6a49277fb6fc29c58b9ea
https://www.pure.ed.ac.uk/ws/files/337450288/PIIS0006322323000550.pdf
https://www.pure.ed.ac.uk/ws/files/337450288/PIIS0006322323000550.pdf
Autor:
Robert F. Hillary, Daniel L. McCartney, Elena Bernabeu, Danni A. Gadd, Yipeng Cheng, Aleksandra D. Chybowska, Hannah M. Smith, Lee Murphy, Nicola Wrobel, Archie Campbell, Rosie M. Walker, Caroline Hayward, Kathryn L. Evans, Andrew M. McIntosh, Riccardo E. Marioni
BackgroundBlood DNA methylation can inform us about the biological mechanisms that underlie common disease states. Previous epigenome-wide analyses of common diseases often focus solely on the prevalence or incidence of individual conditions and rely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04079ee578250e30d274cf67bf95042f
https://doi.org/10.1101/2023.01.10.23284387
https://doi.org/10.1101/2023.01.10.23284387
Autor:
Elena Bernabeu, Konrad Rawlik, Oriol Canela-Xandri, Andrea Talenti, James Prendergast, Albert Tenesa
Publikováno v:
Bernabeu, E, Rawlik, K, Canela-Xandri, O, Talenti, A, Prendergast, J & Tenesa, A 2023, ' Reply to : Genotype by sex interactions in ankylosing spondylitis ', Nature Genetics, vol. 55, no. 1, pp. 17-18 . https://doi.org/10.1038/s41588-022-01251-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e478d63420a0618e65086a85bbccec5
https://hdl.handle.net/20.500.11820/86592d59-52d1-4fdc-9dd8-5e5b4b134b63
https://hdl.handle.net/20.500.11820/86592d59-52d1-4fdc-9dd8-5e5b4b134b63
Autor:
Aleksandra D Chybowska, Danni A Gadd, Yipeng Cheng, Elena Bernabeu, Archie Campbell, Rosie M Walker, Andrew M McIntosh, Nicola Wrobel, Lee Murphy, Paul Welsh, Naveed Sattar, Jackie F Price, Daniel L McCartney, Kathryn L Evans, Riccardo E Marioni
Background and AimsCardiovascular disease (CVD) is among the leading causes of death worldwide. Discovery of new omics biomarkers could help to improve risk stratification algorithms and expand our understanding of molecular pathways contributing to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00102b4c982cb4657f8fec8aa4d397f7
https://doi.org/10.1101/2022.10.21.22281355
https://doi.org/10.1101/2022.10.21.22281355
Adicciones a internet y funciones ejecutivas en estudiantes universitarios: una revisión sistemática
Autor:
Genny Lubrini, Carlos Alberto Marchena Giráldez, Adriana González Pizzio, Elena Bernabeu Brotons
Publikováno v:
Electronic Journal of Research in Education Psychology. 18:613-642
espanolLa adiccion a internet es un problema de salud publica cada vez mayor, y los estudiantes universitarios reunen una serie de caracteristicas que les convierte en poblacion de riesgo. Numerosos estudios sugieren una relacion entre adicciones y a