Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Elena Bekerman"'
Autor:
Bhawna Sharma, Elena Bekerman, Hoa Truong, Johnny Lee, Maria Gamez-Guerrero, Archana Boopathy, Rohit Mital, Katell Bidet Huang, Sarah Ahmadi-Erber, Raphaela Wimmer, Sophie Schulha, Henning Lauterbach, Klaus Orlinger, Silpa Suthram, Mark G. Lewis, Wade Blair, Tariro Makadzange, Romas Geleziunas, Jeffrey P. Murry, Sarah Schmidt
Publikováno v:
Vaccines, Vol 12, Iss 7, p 735 (2024)
Arenavirus-based vectors are being investigated as therapeutic vaccine candidates with the potential to elicit robust CD8 T-cell responses. We compared the immunogenicity of replicating (artPICV and artLCMV) and non-replicating (rPICV and rLCMV) aren
Externí odkaz:
https://doaj.org/article/12cd484f588c476caa2e1468f51b5006
Autor:
Elena Bekerman, Stephen R. Yant, Laurie VanderVeen, Derek Hansen, Bing Lu, William Rowe, Kelly Wang, Christian Callebaut
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 16 (2023)
Long-acting antiretroviral agents for preexposure prophylaxis (PrEP) represent a promising new alternative to daily oral regimens for HIV prevention. Lenacapavir (LEN) is a first-in-class long-acting capsid inhibitor approved for the treatment of HIV
Externí odkaz:
https://doaj.org/article/bd05c3d0d12a411f9917bef6f8371399
Autor:
Po-Ting Liu, Brandon F. Keele, Peter Abbink, Noe B. Mercado, Jinyan Liu, Esther A. Bondzie, Abishek Chandrashekar, Erica N. Borducchi, Joseph Hesselgesser, Michael Mish, Gregory Chin, Elena Bekerman, Romas Geleziunas, Dan H. Barouch
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
The origin and nature of rebound HIV-1 virus following antiretroviral therapy (ART) discontinuation still remains unclear. Here, Liu et al. suggest that intact proviral DNA in peripheral blood and lymph node mononuclear cells during ART suppression l
Externí odkaz:
https://doaj.org/article/4bcf043d109d4ee280c833a2bd8a8741
Autor:
Samuel J. Vidal, Elena Bekerman, Derek Hansen, Bing Lu, Kelly Wang, Judy Mwangi, William Rowe, Federico Campigotto, Jim Zheng, Darryl Kato, Abishek Chandrashekar, Julia Barrett, Shivani Patel, Huahua Wan, Tochi Anioke, Noe B. Mercado, Joseph P. Nkolola, Melissa J. Ferguson, William J. Rinaldi, Christian Callebaut, Wade Blair, Tomas Cihlar, Romas Geleziunas, Stephen R. Yant, Dan H. Barouch
Publikováno v:
Nature
Because no currently available vaccine can prevent HIV infection, pre-exposure prophylaxis (PrEP) with antiretrovirals (ARVs) is an important tool for combating the HIV pandemic1,2. Long-acting ARVs promise to build on the success of current PrEP str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18528a97089342386940b1681f96dfdc
http://europepmc.org/articles/PMC8753592
http://europepmc.org/articles/PMC8753592
Autor:
Rina Barouch-Bentov, Gregory Neveu, Fei Xiao, Melanie Beer, Elena Bekerman, Stanford Schor, Joseph Campbell, Jim Boonyaratanakornkit, Brett Lindenbach, Albert Lu, Yves Jacob, Shirit Einav
Publikováno v:
mBio, Vol 9, Iss 1 (2018)
Externí odkaz:
https://doaj.org/article/7bbed2e53a614c978049c247a9385a33
Publikováno v:
eLife, Vol 7 (2018)
Dengue and Zika viral infections affect millions of people annually and can be complicated by hemorrhage and shock or neurological manifestations, respectively. However, a thorough understanding of the host response to these viruses is lacking, partl
Externí odkaz:
https://doaj.org/article/7ecd020c69f04a72a1f3578b32b0f33e
Autor:
Rina Barouch-Bentov, Gregory Neveu, Fei Xiao, Melanie Beer, Elena Bekerman, Stanford Schor, Joseph Campbell, Jim Boonyaratanakornkit, Brett Lindenbach, Albert Lu, Yves Jacob, Shirit Einav
Publikováno v:
mBio, Vol 7, Iss 6 (2016)
ABSTRACT Enveloped viruses commonly utilize late-domain motifs, sometimes cooperatively with ubiquitin, to hijack the endosomal sorting complex required for transport (ESCRT) machinery for budding at the plasma membrane. However, the mechanisms under
Externí odkaz:
https://doaj.org/article/7638b83bba084ee190baf218083848bc
Autor:
Peter Abbink, Jinyan Liu, Mish Michael R, Po-Ting Liu, Noe B. Mercado, Dan H. Barouch, Joseph Hesselgesser, Elena Bekerman, Erica N. Borducchi, Brandon F. Keele, Abishek Chandrashekar, Gregory Chin, Esther A. Bondzie, Romas Geleziunas
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Nature Communications
Nature Communications
Viral rebound following antiretroviral therapy (ART) discontinuation in HIV-1-infected individuals is believed to originate from a small pool of CD4+ T cells harboring replication-competent provirus. However, the origin and nature of the rebound viru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f1171507b0cb0f660261c5c3bb2e89c
http://link.springer.com/article/10.1038/s41467-020-19254-2
http://link.springer.com/article/10.1038/s41467-020-19254-2
Publikováno v:
PLoS Pathogens, Vol 9, Iss 11, p e1003748 (2013)
Activation-induced cytidine deaminase (AID) is specifically induced in germinal center B cells to carry out somatic hypermutation and class-switch recombination, two processes responsible for antibody diversification. Because of its mutagenic potenti
Externí odkaz:
https://doaj.org/article/f696d7105d1146e191c037433cd0fe67
Autor:
Moupali Das, Christian Callebaut, Darius Babusis, Elena Bekerman, Federico Campigotto, Dan H. Barouch, Stephanie Cox, Tomas Cihlar
Publikováno v:
Journal of Antimicrobial Chemotherapy
ObjectivesCurrent prophylaxis options for people at risk for HIV infection include two US FDA-approved daily pre-exposure prophylaxis (PrEP) regimens and guidelines for a 2-1-1 event-driven course specifically for men who have sex with men. Despite t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::710624eccc52e0cbf0333e3208569c35
https://pubmed.ncbi.nlm.nih.gov/33202006
https://pubmed.ncbi.nlm.nih.gov/33202006