Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Elena B. Soboleva"'
Autor:
Tatyana Y. Postnikova, Alexandra V. Griflyuk, Arseniy S. Zhigulin, Elena B. Soboleva, Oleg I. Barygin, Dmitry V. Amakhin, Aleksey V. Zaitsev
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12621 (2023)
Febrile seizures (FSs) are a relatively common early-life condition that can cause CNS developmental disorders, but the specific mechanisms of action of FS are poorly understood. In this work, we used hyperthermia-induced FS in 10-day-old rats. We de
Externí odkaz:
https://doaj.org/article/600eb257f29746c2afafc762a3061c51
Autor:
Dmitry V. Amakhin, Elena B. Soboleva, Tatiana Yu. Postnikova, Natalia L. Tumanova, Nadezhda M. Dubrovskaya, Daria S. Kalinina, Dmitrii S. Vasilev, Aleksey V. Zaitsev
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Prenatal hypoxia is a widespread condition that causes various disturbances in later life, including aberrant central nervous system development, abnormalities in EEG rhythms, and susceptibility to seizures. Hypoxia in rats on the 14th day of embryog
Externí odkaz:
https://doaj.org/article/91598d2f1b124ec9bc0ee2716dd11318
Autor:
Tatyana Y. Postnikova, Georgy P. Diespirov, Dmitry V. Amakhin, Elizaveta N. Vylekzhanina, Elena B. Soboleva, Aleksey V. Zaitsev
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 24, p 13355 (2021)
Status epilepticus (SE) causes persistent abnormalities in the functioning of neuronal networks, often resulting in worsening epileptic seizures. Many details of cellular and molecular mechanisms of seizure-induced changes are still unknown. The lith
Externí odkaz:
https://doaj.org/article/d7e570e904a64f4282ea39ecdd92d8e9
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 22, p 12174 (2021)
Epileptic activity leads to rapid insertion of calcium-permeable α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (CP-AMPARs) into the synapses of cortical and hippocampal glutamatergic neurons, which generally do not express them. The
Externí odkaz:
https://doaj.org/article/0d194f09872a4b5eac088d1671ef5fee
Autor:
Julia L. Ergina, Dmitry V. Amakhin, Tatyana Y. Postnikova, Elena B. Soboleva, Aleksey V. Zaitsev
Publikováno v:
Biomedicines, Vol 9, Iss 10, p 1374 (2021)
Even brief epileptic seizures can lead to activity-dependent structural remodeling of neural circuitry. Animal models show that the functional plasticity of synapses and changes in the intrinsic excitability of neurons can be crucial for epileptogene
Externí odkaz:
https://doaj.org/article/e75dabb4109b4bdaa5a56c69a1c04020
Autor:
Tatyana Y. Postnikova, Alexandra V. Griflyuk, Dmitry V. Amakhin, Anna A. Kovalenko, Elena B. Soboleva, Olga E. Zubareva, Aleksey V. Zaitsev
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 15, p 8218 (2021)
Febrile seizures (FSs) in early life are significant risk factors of neurological disorders and cognitive impairment in later life. However, existing data about the impact of FSs on the developing brain are conflicting. We aimed to investigate morpho
Externí odkaz:
https://doaj.org/article/8b2510eed9af47869317d2cd471507a7
Autor:
Dmitry V. Amakhin, Elena B. Soboleva, Julia L. Ergina, Sergey L. Malkin, Anton V. Chizhov, Aleksey V. Zaitsev
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Excessive excitation is considered one of the key mechanisms underlying epileptic seizures. We investigated changes in the evoked postsynaptic responses of medial entorhinal cortex (ERC) pyramidal neurons by seizure-like events (SLEs), using the modi
Externí odkaz:
https://doaj.org/article/ace239f64a2c4cbca05ca26a577757b5
Publikováno v:
Pharmaceuticals, Vol 13, Iss 5, p 80 (2020)
Many β-lactam antibiotics, including cephalosporins, may cause neurotoxic and proconvulsant effects. The main molecular mechanism of such effects is considered to be γ-aminobutyric acid type a (GABAa) receptor blockade, leading to the suppression o
Externí odkaz:
https://doaj.org/article/7c106f345ea64069bd66c2cb0d4edeb1
Publikováno v:
Biochemical and biophysical research communications. 623
Potassium ion channels are extensively involved in the regulation of epileptic seizures. The small conductance calcium-sensitive potassium channels (SK channels) and ATP-sensitive potassium (K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00ca3756ccc1554c14e86269ef223476
https://pubmed.ncbi.nlm.nih.gov/35878426
https://pubmed.ncbi.nlm.nih.gov/35878426
Publikováno v:
Neuroscience and Behavioral Physiology. 50:750-761
Epileptiform activity in living brain slices is the result of the complex integration of excitatory and inhibitory synaptic signals. The time pattern of activation of different synaptic conductances during interictal discharges provides a description
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad00329d1f1f4a7561b8c735ae62c6b6
https://doi.org/10.1007/s11055-020-00962-7
https://doi.org/10.1007/s11055-020-00962-7