Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Elena B. Samoilova"'
Publikováno v:
Clinical Immunology. 95:203-211
To determine the roles of Fas/Fas ligand (FasL) in autoimmunity, we studied spontaneous and actively induced autoimmune encephalomyelitis in 541 myelin basic protein-specific T cell receptor transgenic mice. We found that spontaneous autoimmune encep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66beb8524f1a3eabcc20d688b245a334
https://doi.org/10.1006/clim.2000.4861
https://doi.org/10.1006/clim.2000.4861
Publikováno v:
The Journal of Immunology. 163:2937-2943
Experimental autoimmune encephalomyelitis (EAE) is an inflammatory disease of the CNS, which has long been used as an animal model for human multiple sclerosis. Development of autoimmune disease requires coordinated expression of a number of genes th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::532fd224a0d552775d0d623112c922a8
https://doi.org/10.4049/jimmunol.163.5.2937
https://doi.org/10.4049/jimmunol.163.5.2937
Publikováno v:
The Journal of Immunology. 161:6480-6486
Although autoreactive T cells recognizing self myelin Ags are present in most individuals, autoimmune disease of the central nervous system is a relatively rare medical condition. Development of autoimmune disease may require not only the presence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db511f10c9764fed16698184df4a1579
https://doi.org/10.4049/jimmunol.161.12.6480
https://doi.org/10.4049/jimmunol.161.12.6480
Autor:
Howard L. Weiner, Samia J. Khoury, Youhai H. Chen, Elena B. Samoilova, Harry Zhang, J L Horton
Publikováno v:
International Immunology. 10:491-498
Mucosal and systemic administrations of high dose antigens induce long-lasting peripheral T cell tolerance. We and others have shown that high dose peripheral T cell tolerance is mediated by anergy or deletion and is preceded by T cell activation. Co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50bb0f3cb6cb2a1aab1db7e4e1437ec5
https://doi.org/10.1093/intimm/10.4.491
https://doi.org/10.1093/intimm/10.4.491
Publikováno v:
Journal of Molecular Medicine. 75:603-608
Although it is well established that CD40 and its ligand (CD40L) play pivotal roles in the development of humoral immunity, their roles in cell-mediated immunity and cell-mediated autoimmune diseases are not well defined. We report here that CD40:CD4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8877ba69602f461e0725f9f121ddeba
https://doi.org/10.1007/s001090050145
https://doi.org/10.1007/s001090050145
Publikováno v:
Cellular immunology. 190(1)
Intercellular adhesion molecule (ICAM)-1, or CD54, is a member of the immunoglobulin superfamily that binds to lymphocyte function-associated antigen-1 and macrophage-1 antigen. ICAM-1:LFA-1/Mac-1 interaction may be involved in both activation and ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::419749d3e9cdd796ad4294e4ed359aee
https://pubmed.ncbi.nlm.nih.gov/9826450
https://pubmed.ncbi.nlm.nih.gov/9826450
Publikováno v:
Cellular immunology. 188(2)
Experimental autoimmune encephalomyelitis (EAE) is an inflammatory disease of the central nervous system (CNS) which is often used as an animal model for human multiple sclerosis (MS). The disease is mediated by autoreactive lymphocytes recognizing m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7d76de31e4431747fef3006080ddb51
https://pubmed.ncbi.nlm.nih.gov/9756642
https://pubmed.ncbi.nlm.nih.gov/9756642
Autor:
Youhai H. Chen, Haidi Zhang, Hamid Bassiri, Jennifer L. Horton, Simon R. Carding, Peter S. Linsley, Elena B. Samoilova
Publikováno v:
International immunology. 9(11)
Although both B7 and its counter-receptor CD28 are expressed in the thymus, the role of B7 in thymic selection is not clear. We investigated the role of B7 in intrathymic deletion of antigenspecific T cells using a TCR transgenic model specific for a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b64cfada78ce88ae0f7db9c3a43bbf03
https://pubmed.ncbi.nlm.nih.gov/9418127
https://pubmed.ncbi.nlm.nih.gov/9418127
Autor:
Laurence A. Turka, Jennifer L. Horton, Thomas A. Judge, Yiping Yang, Elena B. Samoilova, James M. Wilson, Haidi Zhang, Youhai H. Chen
Both rheumatoid arthritis and animal models of autoimmune arthritis are characterized by hyperactivation of synovial cells and hyperplasia of the synovial membrane. The activated synovial cells produce inflammatory cytokines and degradative enzymes t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa87fed8f7cb3992c2a9770349b92644
https://europepmc.org/articles/PMC508384/
https://europepmc.org/articles/PMC508384/
