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of 10
pro vyhledávání: '"Elena Axelman"'
Autor:
Suheir Assady, Joel Alter, Elena Axelman, Yaniv Zohar, Edmond Sabo, Michael Litvak, Marielle Kaplan, Neta Ilan, Israel Vlodavsky, Zaid Abassi
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119610 (2015)
Heparanase, an endoglycosidase that cleaves heparan sulfate (HS), is involved in various biologic processes. Recently, an association between heparanase and glomerular injury was suggested. The present study examines the involvement of heparanase in
Externí odkaz:
https://doaj.org/article/18aa5c31653c473a9efba9a2082f803a
Heparanase procoagulant activity as a predictor of wound necrosis following diabetic foot amputation
Autor:
Tali Banker Portal, Elena Axelman, Benjamin Brenner, Eli Peled, Doron Norman, Eyal Melamed, Yona Nadir
Publikováno v:
Thrombosis Research. 139:148-153
Trans-metatarsal operation to diabetic foot necrosis is a common procedure although only half of the patients do not need a second amputation due to surgery wound ischemia. No current tools are available for early prediction of surgery success and th
Autor:
Elena Axelman, Mifleh Tatour, Benjamin Brenner, Ma'anit Shapira, Lilach Bonstein, Shourouk Ghanem, Anat Keren-Politansky, Yona Nadir
Publikováno v:
Thrombosis and haemostasis. 117(7)
SummaryHeparanase, known to be involved in angiogenesis and metastasis, was shown to form a complex with tissue factor (TF) and to enhance the generation of factor Xa. Platelets and granulocytes contain abundant amounts of heparanase that may enhance
Autor:
Benjamin Brenner, Inna Kogan, Yona Nadir, Elena Axelman, Mifleh Tatour, Yonatan Crispel, Neta Nevo
Publikováno v:
Thrombosis and haemostasis. 116(4)
SummaryHeparanase is implicated in angiogenesis and tumour progression. We previously demonstrated that heparanase might also affect the haemostatic system in a non-enzymatic manner. It forms a complex and enhances the activity of the blood coagulati
Publikováno v:
Thrombosis Research. 130:129-134
Abstract 3333 Background: Orthopedic hip and knee surgeries are followed by a hypercoagulable state. Heparanase is implicated in inflammation, coagulation activation and angiogenesis. Recently, heparanase was shown to directly interact with tissue fa
Publikováno v:
Thrombosis and haemostasis. 115(1)
SummaryPatients with polycythaemia vera (PV), essential thrombocythaemia (ET) and primary myelofibrosis (PMF) are at increased risk of arterial and venous thrombosis. In patients with ET a positive correlation was observed between JAK-2 V617F mutatio
Autor:
Yonatan Crispel, Israel Henig, Jin-Ping Li, Yona Nadir, Judith Attias, Israel Vlodavsky, Benjamin Brenner, Elena Axelman
Publikováno v:
Thrombosis and haemostasis. 112(3)
SummaryHeparanase is implicated in cell invasion, tumour metastasis and angiogenesis. It forms a complex and enhances the activity of the blood coagulation initiator – tissue factor (TF). We describe new peptides derived from the solvent accessible
Autor:
Marielle Kaplan, Joel Alter, Edmond Sabo, Yaniv Zohar, Israel Vlodavsky, Zaid Abassi, Suheir Assady, Neta Ilan, Elena Axelman, Michael Litvak
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 3, p e0119610 (2015)
PLoS ONE, Vol 10, Iss 3, p e0119610 (2015)
Background Heparanase, an endoglycosidase that cleaves heparan sulfate (HS), is involved in various biologic processes. Recently, an association between heparanase and glomerular injury was suggested. The present study examines the involvement of hep
Publikováno v:
Human reproduction (Oxford, England). 28(9)
STUDY QUESTION: What is the effect of estrogen on heparanase procogulant activity? SUMMARY ANSWER: Estrogen increases heparanase procoagulant activity. WHAT IS KNOWN ALREADY: Estrogen therapy increases the risk of thrombosis and was previously found
Publikováno v:
Blood. 118:378-378
Abstract 378 Background: Heparanase that is abundant in platelets and neutrophils is implicated in cell invasion, tumor metastasis and angiogenesis. Recently, we demonstrated that heparanase is directly involved in the regulation of the hemostatic sy