Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Elena A. Oussatcheva"'
Autor:
Viatcheslav A. Soldatenkov, Elena A. Oussatcheva, Yuri L. Lyubchenko, Luda S. Shlyakhtenko, Vladimir N. Potaman, Irina Lonskaya
Publikováno v:
Journal of Biological Chemistry. 280:17076-17083
Poly(ADP-ribose) polymerase-1 (PARP-1) is an intracellular sensor of DNA strand breaks and plays a critical role in cellular responses to DNA damage. In normally functioning cells, PARP-1 enzymatic activity has been linked to the alterations in chrom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba78a911874a8da3d12e9eac03f4ddbb
https://doi.org/10.1074/jbc.m413483200
https://doi.org/10.1074/jbc.m413483200
Autor:
Bernard A. Brown, Alexander Y. Lushnikov, Richard R. Sinden, Yuri L. Lyubchenko, Vladimir N. Potaman, Elena A. Oussatcheva
Publikováno v:
Nucleic Acids Research. 32:4704-4712
Interest to the left-handed DNA conformation has been recently boosted by the findings that a number of proteins contain the Zalpha domain, which has been shown to specifically recognize Z-DNA. The biological function of Zalpha is presently unknown,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc27b3732acd86342582f421a79d5080
https://doi.org/10.1093/nar/gkh810
https://doi.org/10.1093/nar/gkh810
Autor:
Richard R. Sinden, Sanjay I. Bidichandani, Elena A. Oussatcheva, Yuri L. Lyubchenko, T. Ashizawa, Vladimir N. Potaman, Luda S. Shlyakhtenko
Publikováno v:
Nucleic Acids Research. 32:1224-1231
More than 15 human genetic diseases have been associated with the expansion of trinucleotide DNA repeats, which may involve the formation of non-duplex DNA structures. The slipped-strand nucleation of duplex DNA within GC-rich trinucleotide repeats m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::404bb6f0f0cce790b88efd1304a7406a
https://doi.org/10.1093/nar/gkh274
https://doi.org/10.1093/nar/gkh274
Autor:
Elena A. Oussatcheva, Yuri L. Lyubchenko, John J. Bissler, Vladimir N. Potaman, Vera I. Hashem, Lu Lu, Richard R. Sinden, Craig J. Benham, Tohru Matsuura, Luda S. Shlyakhtenko, Michael Leffak, Tetsuo Ashizawa
Publikováno v:
Journal of Molecular Biology. 326:1095-1111
A number of human hereditary diseases have been associated with the instability of DNA repeats in the genome. Recently, spinocerebellar ataxia type 10 has been associated with expansion of the pentanucleotide repeat (ATTCT)(n).(AGAAT)(n) from a norma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49c9797eb433444080563391d4ffa6fa
https://doi.org/10.1016/s0022-2836(03)00037-8
https://doi.org/10.1016/s0022-2836(03)00037-8
Autor:
Luda S. Shlyakhtenko, Vladimir N. Potaman, Elena A. Oussatcheva, Richard R. Sinden, Ross Glass, Yuri L. Lyubchenko
Publikováno v:
Journal of Molecular Biology. 292:75-86
DNA heteroduplexes as models for slipped strand DNA have been analyzed by polyacrylamide gel migration and atomic force microscopy (AFM). All heteroduplexes containing one hairpin or loop have reduced electrophoretic mobilities compared with that exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b239df36e78f69fdf901a025cc6538cd
https://doi.org/10.1006/jmbi.1999.3043
https://doi.org/10.1006/jmbi.1999.3043
Autor:
Alexander Y. Lushnikov, Yuri L. Lyubchenko, Vladimir N. Potaman, Elena A. Oussatcheva, Richard R. Sinden
Publikováno v:
Biochemistry. 45(1)
The SfiI restriction enzyme binds to DNA as a tetramer holding two usually distant DNA recognition sites together before cleavage of the four DNA strands. To elucidate structural properties of the SfiI-DNA complex, atomic force microscopy (AFM) imagi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08efb376574baac3720d81ffd5aa376e
https://pubmed.ncbi.nlm.nih.gov/16388590
https://pubmed.ncbi.nlm.nih.gov/16388590
Autor:
Vladimir N. Potaman, Viatcheslav A. Soldatenkov, Luda S. Shlyakhtenko, Yuri L. Lyubchenko, Elena A. Oussatcheva
Publikováno v:
Journal of molecular biology. 348(3)
Poly(ADP-ribose) polymerase-1 (PARP-1) participates in DNA cleavage and rejoining-dependent reactions, such as DNA replication, recombination and repair. PARP-1 is also important in transcriptional regulation, although the determinants for its bindin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e15f213945c35b4700bc2b4b36af1237
https://pubmed.ncbi.nlm.nih.gov/15826658
https://pubmed.ncbi.nlm.nih.gov/15826658
Autor:
Vladimir N. Potaman, Otto F. Sankey, Richard R. Sinden, Yuri L. Lyubchenko, Elena A. Oussatcheva, Jeffrey W. Pavlicek
Publikováno v:
Biochemistry. 43(33)
Local DNA bending is a critical factor for numerous DNA functions including recognition of DNA by sequence-specific regulatory binding proteins. Negative DNA supercoiling increases both local and global DNA dynamics, and this dynamic flexibility can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6614faf3ac6f7a3bdb5a370ed6e974db
https://pubmed.ncbi.nlm.nih.gov/15311927
https://pubmed.ncbi.nlm.nih.gov/15311927
Autor:
Otto F. Sankey, Richard R. Sinden, Vladimir N. Potaman, Yuri L. Lyubchenko, Elena A. Oussatcheva, Jeffrey W. Pavlicek
Publikováno v:
Journal of molecular biology. 338(4)
DNA supercoiling plays an important role in many genetic processes such as replication, transcription, and recombination. Supercoiling provides energy for helix un-pairing and drives the formation of alternative DNA structural transitions, like cruci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c12cefaad8cc0e130835b4420ecad50
https://pubmed.ncbi.nlm.nih.gov/15099741
https://pubmed.ncbi.nlm.nih.gov/15099741
Autor:
Luda S. Shlyakhtenko, Vladimir N. Potaman, Elena A. Oussatcheva, Richard R. Sinden, Yuri L. Lyubchenko, Christopher E. Pearson
Publikováno v:
Journal of biosciences. 27(1 Suppl 1)
Fourteen genetic neurodegenerative diseases and three fragile sites have been associated with the expansion of (CTG)n•(CAG)n, (CGG)n•(CCG)n, or (GAA)n•(TTC)n repeat tracts. Different models have been proposed for the expansion of triplet repeat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a32aba707893fbcc4a1fe1fc61c250e
https://pubmed.ncbi.nlm.nih.gov/11927777
https://pubmed.ncbi.nlm.nih.gov/11927777