Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Elena, Velkoska"'
Autor:
Bronwyn A. Kingwell, Danielle Duffy, Regina Clementi, Elena Velkoska, John Feaster, C. Michael Gibson
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 9 (2024)
Externí odkaz:
https://doaj.org/article/d00adc5ec7994cd5a0831b5d186ae041
Autor:
Bronwyn A. Kingwell, Stephen J. Nicholls, Elena Velkoska, Svetlana A. Didichenko, Danielle Duffy, Serge Korjian, C. Michael Gibson
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 8 (2022)
Approximately 12% of patients with acute myocardial infarction (AMI) experience a recurrent major adverse cardiovascular event within 1 year of their primary event, with most occurring within the first 90 days. Thus, there is a need for new therapeut
Externí odkaz:
https://doaj.org/article/b3632ad952644828a192fd9015e426e9
Autor:
Svetlana A. Didichenko, Elena Velkoska, Alexei V. Navdaev, Brandon H. Greene, Shuhui Wang Lorkowski, Danielle Duffy, Sojaita J. Mears, Samuel D. Wright, C. Michael Gibson, Jonathan D. Smith, Bronwyn A. Kingwell
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 43:855-869
Background: To characterize the effects of CSL112 (human APOA1 [apolipoprotein A1]) on the APOA1 exchange rate (AER) and the relationships with specific HDL (high-density lipoprotein) subpopulations when administered in the 90-day high-risk period po
Autor:
Sheila K. Patel, Elena Velkoska, Daniel Gayed, Jay Ramchand, Jessica Lesmana, Louise M. Burrell
Publikováno v:
BMC Nephrology, Vol 19, Iss 1, Pp 1-8 (2018)
Abstract Background Left ventricular hypertrophy (LVH) increases the risk of death in chronic kidney disease (CKD). The transcription factor Kruppel-like factor 15 (KLF15) is expressed in the heart and regulates cardiac remodelling through inhibition
Externí odkaz:
https://doaj.org/article/e99a810526444f6bb50a14986d88e4b3
Autor:
Sheila K. Patel, Bryan Wai, Chim C. Lang, Daniel Levin, Colin N.A. Palmer, Helen M. Parry, Elena Velkoska, Stephen B. Harrap, Piyush M. Srivastava, Louise M. Burrell
Publikováno v:
EBioMedicine, Vol 18, Iss C, Pp 171-178 (2017)
Left ventricular (LV) hypertrophy (LVH) is a heritable trait that is common in type 2 diabetes and is associated with the development of heart failure. The transcriptional factor Kruppel like factor 15 (KLF15) is expressed in the heart and acts as a
Externí odkaz:
https://doaj.org/article/909314484a354cd0989220dc8640388f
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171975 (2017)
We previously reported that exogenous angiotensin (Ang) 1-7 has adverse cardiac effects in experimental kidney failure due to its action to increase cardiac angiotensin converting enzyme (ACE) activity. This study investigated if the addition of an A
Externí odkaz:
https://doaj.org/article/1caef017d37742fc81850f7407c6eb0c
Publikováno v:
Journal of Hypertension
Objective This study conducted exploratory metabolomic and lipidomic profiling of plasma samples from the DASH (Dietary Approaches to Stop Hypertension) Sodium Trial to identify unique plasma biomarkers to identify salt-sensitive versus salt-resistan
Autor:
Terase F Lancefield, Sheila K Patel, Melanie Freeman, Elena Velkoska, Bryan Wai, Piyush M Srivastava, Mark Horrigan, Omar Farouque, Louise M Burrell
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0161715 (2016)
Upregulation of the receptor for advanced glycation end products (RAGE) has been proposed as a pathophysiological mechanism underlying the development of atrial fibrillation (AF). We sought to investigate if soluble RAGE levels are associated with AF
Externí odkaz:
https://doaj.org/article/78ef832a269245d593e7b41cd37e7c14
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161760 (2016)
Angiotensin converting enzyme (ACE) 2 is a negative regulator of the renin angiotensin system (RAS) through its role to degrade angiotensin II. In rats with subtotal nephrectomy (STNx), adverse cardiac remodelling occurs despite elevated cardiac ACE2
Externí odkaz:
https://doaj.org/article/d9ac9eedec71496a887996545c621730
Autor:
Roslyn, Davis, Elena, Velkoska, Helen, McCallum, Belinda, Majcen, Andreas, Gille, Bronwyn A, Kingwell, Kirstee, Martin
Publikováno v:
Journal of Immunological Methods. 513:113411
There are numerous challenges encountered during clinical testing for an immunogenic response to a plasma-derived therapeutic. Distinguishing between antibodies that recognize endogenous versus therapeutic protein can be particularly difficult. This