Novel indolic AMPK modulators induce vasodilatation through activation of the AMPK–eNOS–NO pathway

Autor: Marta Sanz-Gómez, Elnaz Aledavood, Marina Beroiz-Salaverri, Laura Lagartera, Elena Vega-Martín, Marta Gil-Ortega, Jose Cumella, Concepción Pérez, Francisco Javier Luque, Carolina Estarellas, María S. Fernández-Alfonso, Ana Castro

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)

Abstract Endothelial adenosine monophosphate-activated protein kinase (AMPK) plays a critical role in the regulation of vascular tone through stimulating nitric oxide (NO) release in endothelial cells. Since obesity leads to endothelial dysfunction a

Externí odkaz: https://doaj.org/article/795794dd6bc446a9849f23d01814c260

Imbalance in Bone Morphogenic Proteins 2 and 7 Is Associated with Renal and Cardiovascular Damage in Chronic Kidney Disease

Autor: Francisco Javier Manzano-Lista, Marta Sanz-Gómez, Daniel González-Moreno, Elena Vega-Martín, Marta Gil-Ortega, Angela Schulz, Miguel Ángel Rubio, Gema Ruiz-Hurtado, Luis Miguel Ruilope, Isabel Aránguez, Reinhold Kreutz, María S. Fernández-Alfonso

Publikováno v: International Journal of Molecular Sciences, Vol 24, Iss 1, p 40 (2022)

Arterial stiffness is a major vascular complication of chronic kidney disease (CKD). The development of renal damage, hypertension, and increased pulse wave velocity (PWV) in CKD might be associated with an imbalance in bone morphogenetic proteins (B

Externí odkaz: https://doaj.org/article/f30c20cf5493428eba2355c43b273db7

Differential Deleterious Impact of Highly Saturated Versus Monounsaturated Fat Intake on Vascular Function, Structure, and Mechanics in Mice

Autor: Elena Vega-Martín, Marta Gil-Ortega, Raquel González-Blázquez, Sara Benedito, Jesús Fernández-Felipe, Mariano Ruiz-Gayo, Nuria del Olmo, Julie A. Chowen, Laura M. Frago, Beatriz Somoza, María S. Fernández-Alfonso

Publikováno v: Nutrients, Vol 13, Iss 3, p 1003 (2021)

Vegetable oils such as palm oil (enriched in saturated fatty acids, SFA) and high-oleic-acid sunflower oil (HOSO, containing mainly monounsaturated fatty acids, MUFA) have emerged as the most common replacements for trans-fats in the food industry. T

Externí odkaz: https://doaj.org/article/7d07827153ee48ad83f4fce9c6e86bed

IMBALANCE IN BONE MORPHOGENIC PROTEINS 2 AND 7 IS ASSOCIATED WITH HYPERTENSION AND ARTERIAL STIFFNESS IN CHRONIC KIDNEY DISEASE

Autor: Francisco J. Manzano-Lista, Marta Sanz-Gómez, Daniel González-Moreno, Elena Vega-Martín, Marta Gil-Ortega, Isabel Aránguez, Angela Schulz, Miguel Ángel Rubio, Gema Ruiz-Hurtado, Luis M. Ruilope, Reinhold Kreutz, María S. Fernández-Alfonso

Publikováno v: Journal of Hypertension. 40:e81

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ca87cf4afb36d6bcbd98e648483669d1
https://doi.org/10.1097/01.hjh.0000835992.77414.e5

Differential Deleterious Impact of Highly Saturated Versus Monounsaturated Fat Intake on Vascular Function, Structure, and Mechanics in Mice

Autor: Mariano Ruiz-Gayo, Sara Benedito, María S. Fernández-Alfonso, Nuria Del Olmo, Raquel González-Blázquez, Laura M. Frago, Beatriz Somoza, Marta Gil-Ortega, Elena Vega-Martín, Jesús Fernández-Felipe, Julie A. Chowen

Publikováno v: Nutrients
Volume 13
Issue 3
Nutrients, Vol 13, Iss 1003, p 1003 (2021)
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
E-Prints Complutense. Archivo Institucional de la UCM

Vegetable oils such as palm oil (enriched in saturated fatty acids, SFA) and high‐oleic‐acid sunflower oil (HOSO, containing mainly monounsaturated fatty acids, MUFA) have emerged as the most common replacements for trans‐fats in the food indus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae81dda6665a25f2cf4289104975486b
https://pubmed.ncbi.nlm.nih.gov/33808927