Zobrazeno 1 - 10
of 182
pro vyhledávání: '"Elena, Hidalgo"'
Publikováno v:
PLoS Genetics, Vol 20, Iss 6, p e1011316 (2024)
Splicing is an important step of gene expression regulation in eukaryotes, as there are many mRNA precursors that can be alternatively spliced in different tissues, at different cell cycle phases or under different external stimuli. We have developed
Externí odkaz:
https://doaj.org/article/cbcaa6af37cf4fb8a79967a589a13e90
Autor:
Maribel Marquina, Eva Lambea, Mercé Carmona, Marta Sánchez-Marinas, Sandra López-Aviles, José Ayte, Elena Hidalgo, Rosa Aligue
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract The fission yeast mitogen-activated kinase (MAPK) Sty1 is essential for cell survival in response to different environmental insults. In unstimulated cells, Sty1 forms an inactive ternary cytoplasmatic complex with the MAPKK Wis1 and the MAP
Externí odkaz:
https://doaj.org/article/e0ab4fd062ad49d6810124cb31b60fd6
Autor:
Montserrat Vega, David Castillo, Laura de Cubas, Yirong Wang, Ying Huang, Elena Hidalgo, Margarita Cabrera
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-18 (2022)
Abstract Background In many organisms, aging is characterized by a loss of mitochondrial homeostasis. Multiple factors such as respiratory metabolism, mitochondrial fusion/fission, or mitophagy have been linked to cell longevity, but the exact impact
Externí odkaz:
https://doaj.org/article/1f2e0db6cab3415980ae66b1c2f67942
Publikováno v:
Antioxidants, Vol 12, Iss 10, p 1810 (2023)
Aging is characterized by a number of hallmarks including loss of mitochondrial homeostasis and decay in stress tolerance, among others. Unicellular eukaryotes have been widely used to study chronological aging. As a general trait, calorie restrictio
Externí odkaz:
https://doaj.org/article/ccdcd0e2263f41f9a9e9e7f921f1eb6c
Autor:
Jarmila Princová, Clàudia Salat-Canela, Petr Daněk, Anna Marešová, Laura de Cubas, Jürg Bähler, José Ayté, Elena Hidalgo, Martin Převorovský
Publikováno v:
PLoS Genetics, Vol 19, Iss 1, p e1010582 (2023)
Oxidative stress is associated with cardiovascular and neurodegenerative diseases, diabetes, cancer, psychiatric disorders and aging. In order to counteract, eliminate and/or adapt to the sources of stress, cells possess elaborate stress-response mec
Externí odkaz:
https://doaj.org/article/6b3f0849a4714c1bbcf92b9f304769a0
Autor:
Sergio Diez-Hermano, Farooq Ahmad, Jonatan Niño-Sanchez, Alvaro Benito, Elena Hidalgo, Laura Morejón Escudero, Wilson Acosta Morel, Julio Javier Diez
Publikováno v:
Frontiers in Forests and Global Change, Vol 5 (2022)
IntroductionMediterranean forests are currently facing a surge in abiotic stressors such as droughts and massive fires as a result of climate crisis and human pressure. Susceptibility to biotic stressors has also increased, including a variety of pes
Externí odkaz:
https://doaj.org/article/eb0c7bc7697c4004b8951422f1325098
Publikováno v:
iScience, Vol 25, Iss 8, Pp 104820- (2022)
Summary: The MAP kinase Sty1 phosphorylates and activates the transcription factor Atf1 in response to several stress conditions, which then shifts from a transcriptional repressor to an activator. Atf1 also participates in heterochromatin assembly a
Externí odkaz:
https://doaj.org/article/e2ad93eac4bb47b3bbaf73dcb9051cd9
Autor:
Laura de Cubas, Jorge Mallor, Víctor Herrera-Fernández, José Ayté, Rubén Vicente, Elena Hidalgo
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 706 (2023)
Intracellular hydrogen peroxide (H2O2) levels can oscillate from low, physiological concentrations, to intermediate, signaling ones, and can participate in toxic reactions when overcoming certain thresholds. Fluorescent protein-based reporters to mea
Externí odkaz:
https://doaj.org/article/ddb97ed7f79644bd8919147c056a2382
Publikováno v:
Islas, Vol 62, Iss 197, Pp 111-127 (2021)
La pertinencia de las crónicas de viaje como fuente para las ciencias históricas constituye un asunto pendiente para la historiografía santiaguera. El presente artículo ofrece un bosquejo panorámico sobre las crónicas de viaje que reflejaron m
Externí odkaz:
https://doaj.org/article/04b3628ac71342a985b3cad24e877527
Autor:
Clàudia Salat-Canela, Mercè Carmona, Rebeca Martín-García, Pilar Pérez, José Ayté, Elena Hidalgo
Publikováno v:
Cell Reports, Vol 37, Iss 5, Pp 109951- (2021)
Summary: Cdc42 GTPase rules cell polarity and growth in fission yeast. It is negatively and positively regulated by GTPase-activating proteins (GAPs) and guanine nucleotide exchange factors (GEFs), respectively. Active Cdc42-GTP localizes to the pole
Externí odkaz:
https://doaj.org/article/6387bfcfd2c149ada5f5a78fed45275b