Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Elena, Dreassi"'
Autor:
Giusy Tassone, Samuele Maramai, Marco Paolino, Stefania Lamponi, Federica Poggialini, Elena Dreassi, Elena Petricci, Stefano Alcaro, Cecilia Pozzi, Isabella Romeo
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Bioconjugation is one of the most promising strategies to improve drug delivery, especially in cancer therapy. Biomolecules such as bile acids (BAs) have been intensively explored as carriers, due to their peculiar physicochemical properties
Externí odkaz:
https://doaj.org/article/1a4c84aa763544cdb95cf8741a3df437
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 14, p 7588 (2024)
Globalization and climate change are both contributing to an increase in the number of potentially invasive algae in coastal areas. In terms of biodiversity and financial losses, the invasiveness of algae has become a significant issue in Orbetello L
Externí odkaz:
https://doaj.org/article/1280146da9424cde821d3a1fe1262157
Autor:
Luisa Frusciante, Michela Geminiani, Alfonso Trezza, Tommaso Olmastroni, Pierfrancesco Mastroeni, Laura Salvini, Stefania Lamponi, Andrea Bernini, Daniela Grasso, Elena Dreassi, Ottavia Spiga, Annalisa Santucci
Publikováno v:
Marine Drugs, Vol 22, Iss 5, p 226 (2024)
Utilizing plant-based resources, particularly their by-products, aligns with sustainability principles and circular bioeconomy, contributing to environmental preservation. The therapeutic potential of plant extracts is garnering increasing interest,
Externí odkaz:
https://doaj.org/article/2b341c8733dd4dcb82e29a840502a53a
Autor:
Silvia Cesarini, Ilaria Vicenti, Federica Poggialini, Silvia Filippi, Eleonora Mancin, Lia Fiaschi, Elisa De Marchi, Federica Giammarino, Chiara Vagaggini, Bruno Mattia Bizzarri, Raffaele Saladino, Elena Dreassi, Maurizio Zazzi, Lorenzo Botta
Publikováno v:
Molecules, Vol 29, Iss 7, p 1452 (2024)
The use of privileged scaffolds as a starting point for the construction of libraries of bioactive compounds is a widely used strategy in drug discovery and development. Scaffold decoration, morphing and hopping are additional techniques that enable
Externí odkaz:
https://doaj.org/article/e3ec79e5c0fa472db93d562a43145464
Autor:
Luisa Maresca, Enrica Crivaro, Francesca Migliorini, Giulia Anichini, Alessandro Giammona, Sara Pepe, Federica Poggialini, Chiara Vagaggini, Giuseppe Giannini, Serena Sestini, Lorenzo Borgognoni, Andrea Lapucci, Elena Dreassi, Maurizio Taddei, Fabrizio Manetti, Elena Petricci, Barbara Stecca
Publikováno v:
Pharmacological Research, Vol 195, Iss , Pp 106858- (2023)
Aberrant activation of Hedgehog (HH) signaling in cancer is the result of genetic alterations of upstream pathway components (canonical) or other oncogenic mechanisms (noncanonical), that ultimately concur to activate the zinc-finger transcription fa
Externí odkaz:
https://doaj.org/article/3edd0903f8c04391913aff178e1c0782
Publikováno v:
Chemistry, Vol 4, Iss 4, Pp 1714-1722 (2022)
A single clean, good-yielding, environment-friendly microwave-assisted procedure for O-silylation of uridine with tert-butyldimethylsilyl chloride (TBDMSCl), 1,8-Diazabicyclo(5.4.0)undec-7-ene (DBU) and potassium nitrate as catalyst under solvent-fre
Externí odkaz:
https://doaj.org/article/d40d8606b78c4392ae37610bfd191298
Autor:
Alfonso Trezza, Michela Geminiani, Giuseppe Cutrera, Elena Dreassi, Luisa Frusciante, Stefania Lamponi, Ottavia Spiga, Annalisa Santucci
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 2517 (2024)
Currently, many environmental and energy-related problems are threatening the future of our planet. In October 2022, the Worldmeter recorded the world population as 7.9 billion people, estimating that there will be an increase of 2 billion by 2057. T
Externí odkaz:
https://doaj.org/article/e219d116cdee416e9b07bd9e17193176
Identification of Novel Non-Nucleoside Inhibitors of Zika Virus NS5 Protein Targeting MTase Activity
Autor:
Diego Fiorucci, Micaela Meaccini, Giulio Poli, Maria Alfreda Stincarelli, Chiara Vagaggini, Simone Giannecchini, Priscila Sutto-Ortiz, Bruno Canard, Etienne Decroly, Elena Dreassi, Annalaura Brai, Maurizio Botta
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 2437 (2024)
Zika virus (ZIKV) is a positive-sense single-stranded virus member of the Flaviviridae family. Among other arboviruses, ZIKV can cause neurological disorders such as Guillain Barré syndrome, and it can have congenital neurological manifestations and
Externí odkaz:
https://doaj.org/article/0afb7cf099f34ac8aef2b89648debb2a
Autor:
Federica Poggialini, Chiara Vagaggini, Annalaura Brai, Claudia Pasqualini, Anna Carbone, Francesca Musumeci, Silvia Schenone, Elena Dreassi
Publikováno v:
Pharmaceuticals, Vol 16, Iss 11, p 1527 (2023)
Although patients would rather oral therapies to injections, the gastrointestinal tract’s low permeability makes this method limiting for most compounds, including anticancer drugs. Due to their low bioavailability, oral antitumor therapies suffer
Externí odkaz:
https://doaj.org/article/0c24052588a24c2d985bde16104856df
Autor:
Marisanna Centini, Isabel Martinez-Sañudo, Marco Biagi, Elena Dreassi, Luca Mazzon, Laura Marri
Publikováno v:
Cosmetics, Vol 10, Iss 4, p 103 (2023)
In recent years, the exploitation of bacteria for the production of carotenoids has become of great interest as a sustainable alternative to chemical synthesis, which is expensive and technically challenging. This study contributes to the repertoire
Externí odkaz:
https://doaj.org/article/77c073b879064600af92b59823e83f5f