Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Elena, Cambria"'
Autor:
Giovanni S. Offeddu, Elena Cambria, Sarah E. Shelton, Kristina Haase, Zhengpeng Wan, Luca Possenti, Huu Tuan Nguyen, Mark R. Gillrie, Dean Hickman, Charles G. Knutson, Roger D. Kamm
Publikováno v:
Advanced Science, Vol 11, Iss 38, Pp n/a-n/a (2024)
Abstract Desmoplasia in breast cancer leads to heterogeneity in physical properties of the tissue, resulting in disparities in drug delivery and treatment efficacy among patients, thus contributing to high disease mortality. Personalized in vitro bre
Externí odkaz:
https://doaj.org/article/a394968a50cf4ecb907cb7897f5472c7
Autor:
Andrea Mainardi, Elena Cambria, Paola Occhetta, Ivan Martin, Andrea Barbero, Stefan Schären, Arne Mehrkens, Olga Krupkova
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2022)
Discogenic back pain is one of the most diffused musculoskeletal pathologies and a hurdle to a good quality of life for millions of people. Existing therapeutic options are exclusively directed at reducing symptoms, not at targeting the underlying, s
Externí odkaz:
https://doaj.org/article/315d63e15b7240869a664d72a942386b
Autor:
Elena Cambria, Sally Heusser, Ariane C. Scheuren, Wai Kit Tam, Agnieszka A. Karol, Wolfgang Hitzl, Victor Y. Leung, Ralph Müller, Stephen J. Ferguson, Karin Wuertz‐Kozak
Publikováno v:
JOR Spine, Vol 4, Iss 3, Pp n/a-n/a (2021)
Abstract Background Aberrant mechanical loading of the spine causes intervertebral disc (IVD) degeneration and low back pain. Current therapies do not target the mediators of the underlying mechanosensing and mechanotransduction pathways, as these ar
Externí odkaz:
https://doaj.org/article/09a1027dccf34b24b75d28616132c272
Autor:
Elena Cambria, Silvio Brunner, Sally Heusser, Philipp Fisch, Wolfgang Hitzl, Stephen J. Ferguson, Karin Wuertz-Kozak
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
The increasing investigation of cellular mechanotransduction mechanisms requires biomaterials combining biofunctionality and suitable mechanical properties. Agarose is a standard biomaterial for cartilage and intervertebral disc mechanobiology studie
Externí odkaz:
https://doaj.org/article/537c3d3d76fb4878bc66c3819c9dbe16
Autor:
Elena Cambria, Francesco S. Pasqualini, Petra Wolint, Julia Günter, Julia Steiger, Annina Bopp, Simon P. Hoerstrup, Maximilian Y. Emmert
Publikováno v:
npj Regenerative Medicine, Vol 2, Iss 1, Pp 1-10 (2017)
Abstract Acute myocardial infarction and chronic heart failure rank among the major causes of morbidity and mortality worldwide. Except for heart transplantation, current therapy options only treat the symptoms but do not cure the disease. Stem cell-
Externí odkaz:
https://doaj.org/article/07ba522561994afbb43f824efa0bb64a
Autor:
Elena Cambria, Matthias J. E. Arlt, Sandra Wandel, Olga Krupkova, Wolfgang Hitzl, Fabian S. Passini, Oliver N. Hausmann, Jess G. Snedeker, Stephen J. Ferguson, Karin Wuertz-Kozak
Publikováno v:
Cells, Vol 9, Iss 7, p 1736 (2020)
Mechanical loading and inflammation interact to cause degenerative disc disease and low back pain (LBP). However, the underlying mechanosensing and mechanotransductive pathways are poorly understood. This results in untargeted pharmacological treatme
Externí odkaz:
https://doaj.org/article/55ba19fd9cee4acc986df1334826d34c
Publikováno v:
JOR Spine, Vol 1, Iss 1, Pp n/a-n/a (2018)
The CRISPR/Cas9 system has emerged as a powerful tool for mammalian genome engineering. In basic and translational intervertebral disc (IVD) research, this technique has remarkable potential to answer fundamental questions on pathway interactions, to
Externí odkaz:
https://doaj.org/article/51074e4186864c26b4a94b0a5469daa5
Autor:
Julia Günter, Petra Wolint, Annina Bopp, Julia Steiger, Elena Cambria, Simon P. Hoerstrup, Maximilian Y. Emmert
Publikováno v:
Stem Cells International, Vol 2016 (2016)
More people die annually from cardiovascular diseases than from any other cause. In particular, patients who suffer from myocardial infarction may be affected by ongoing adverse remodeling processes of the heart that may ultimately lead to heart fail
Externí odkaz:
https://doaj.org/article/267268849cb84eccb17ad5dd4acf1369
Autor:
Andrea, Mainardi, Elena, Cambria, Paola, Occhetta, Ivan, Martin, Andrea, Barbero, Stefan, Schären, Arne, Mehrkens, Olga, Krupkova
Publikováno v:
Frontiers in bioengineering and biotechnology. 9
Discogenic back pain is one of the most diffused musculoskeletal pathologies and a hurdle to a good quality of life for millions of people. Existing therapeutic options are exclusively directed at reducing symptoms, not at targeting the underlying, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4ddd750fe967802ac51b5c0f43ca8394
https://pubmed.ncbi.nlm.nih.gov/35155416
https://pubmed.ncbi.nlm.nih.gov/35155416
Autor:
Stephen J. Ferguson, Victor Y. L. Leung, Ralph Müller, Agnieszka Karol, Wai Kit Tam, Ariane C. Scheuren, Elena Cambria, Sally Heusser, Karin Wuertz-Kozak, Wolfgang Hitzl
Publikováno v:
JOR Spine, Vol 4, Iss 3, Pp n/a-n/a (2021)
JOR Spine
JOR Spine, 4 (3)
JOR Spine
JOR Spine, 4 (3)
Background Aberrant mechanical loading of the spine causes intervertebral disc (IVD) degeneration and low back pain. Current therapies do not target the mediators of the underlying mechanosensing and mechanotransduction pathways, as these are poorly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3253be5d20089bd93f81a3efb3b2dac7
https://doi.org/10.1002/jsp2.1149
https://doi.org/10.1002/jsp2.1149