Výsledky vyhledávání - "Eleftherios Sachlos"

Collagen scaffolds reinforced with biomimetic composite nano-sized carbonate-substituted hydroxyapatite crystals and shaped by rapid prototyping to contain internal microchannels

Autor: Jan T. Czernuszka, Duce Gotora, Eleftherios Sachlos

The next generation of tissue engineering scaffolds will be made to accommodate blood vessels and nutrient channels to support cell survival deep in the interior of the scaffolds. To this end, we have developed a method that incorporates microchannel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2416fea0d4ea253c6282982fc26336de
https://doi.org/10.1089/ten.2006.12.2479

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A process to make collagen scaffolds with an artificial circulatory system using rapid prototyping

Autor: Jan T. Czernuszka, Chris Ainsley, Eleftherios Sachlos, Nuno M. Reis, Brian Derby

Publikováno v: Scopus-Elsevier

Tissue engineering aims to produce biological substitutes to restore or repair damaged human tissues or organs. The principle strategy behind tissue engineering involves seeding relevant cell(s) onto porous 3D biodegradable scaffolds. The scaffold ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7820c4d7f6dd3dd4d7b23dc8fa51cbbd
https://ora.ox.ac.uk/objects/uuid:67c995cc-3b9b-481d-ad67-29c8b5279b47

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Controlling the processing of collagen-hydroxyapatite scaffolds for bone tissue engineering

Autor: Jan T. Czernuszka, Eleftherios Sachlos, Chaozong Liu, D. A. Wahl

Scaffolds are an important aspect of the tissue engineering approach to tissue regeneration. This study shows that it is possible to manufacture scaffolds from type I collagen with or without hydroxyapatite (HA) by critical point drying. The mean por

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::446f10bce19ab242b9bd67c77f2f191f
https://ora.ox.ac.uk/objects/uuid:351d0415-b6bf-4282-b242-c452a69bf0ca

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Making tissue engineering scaffolds work. Review: the application of solid freeform fabrication technology to the production of tissue engineering scaffolds

Autor: Eleftherios Sachlos, Jan T. Czernuszka

Publikováno v: European Cells & Materials, Vol 5, Pp 29-40 (2003)

Tissue engineering is a new and exciting technique which has the potential to create tissues and organs de novo. It involves the in vitro seeding and attachment of human cells onto a scaffold. These cells then proliferate, migrate and differentiate i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfbc711233e908a09ed914e37997abc5
https://ora.ox.ac.uk/objects/uuid:487b33eb-e25b-4ff9-a81c-568b7f1c57fa

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Potential for Synthesis and Degradation of Extracellular Matrix Proteins by Valve Interstitial Cells Seeded onto Collagen Scaffolds

Autor: Eleftherios Sachlos, Penny S. Thomas, Jan T. Czernuszka, Sally A. Dreger, Patricia M. Taylor, Adrian H. Chester, Magdi H. Yacoub

Publikováno v: Tissue Engineering. 12:2533-2540

Matrix remodeling, which involves proteolytic enzymes, such as the matrix metalloproteinases (MMPs), is of significant importance with respect to tissue engineering a heart valve construct. The ability of valve interstitial cells (ICs) to release the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f45f84ff4699f40ec13219a1861b8b64
https://doi.org/10.1089/ten.2006.12.2533

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