Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Eleftheria, Tsolaki"'
Autor:
Angelos Koutras, Georgios Lazaridis, Georgia-Angeliki Koliou, George Kouvatseas, Christos Christodoulou, Dimitrios Pectasides, Vassiliki Kotoula, Anna Batistatou, Mattheos Bobos, Eleftheria Tsolaki, Kyriaki Papadopoulou, George Pentheroudakis, Pavlos Papakostas, Stavroula Pervana, Kalliopi Petraki, Sofia Chrisafi, Evangelia Razis, Amanda Psyrri, Dimitrios Bafaloukos, Konstantine T Kalogeras, Haralambos P Kalofonos, George Fountzilas
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0207707 (2018)
In the current study, we performed a complete analysis, with four different methods, of all four HER family receptors, in a series of patients with metastatic breast cancer treated with trastuzumab-based regimens and evaluated their prognostic value.
Externí odkaz:
https://doaj.org/article/02859fb3024e4a0f9a806df523249868
Autor:
Vassiliki Kotoula, Aggeliki Lyberopoulou, Kyriaki Papadopoulou, Elpida Charalambous, Zoi Alexopoulou, Chryssa Gakou, Sotiris Lakis, Eleftheria Tsolaki, Konstantinos Lilakos, George Fountzilas
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128818 (2015)
Massively parallel sequencing (MPS) holds promise for expanding cancer translational research and diagnostics. As yet, it has been applied on paraffin DNA (FFPE) with commercially available highly multiplexed gene panels (100s of DNA targets), while
Externí odkaz:
https://doaj.org/article/aee2dfaae82049d791365de507171c0d
Autor:
Vassiliki Kotoula, Mattheos Bobos, Zoi Alexopoulou, Christos Papadimitriou, Kyriaki Papadopoulou, Elpida Charalambous, Eleftheria Tsolaki, Grigorios Xepapadakis, Irene Nicolaou, Irene Papaspirou, Gerasimos Aravantinos, Christos Christodoulou, Ioannis Efstratiou, Helen Gogas, George Fountzilas
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103707 (2014)
BACKGROUND: HER2 and TOP2A gene status are assessed for diagnostic and research purposes in breast cancer with fluorescence in situ hybridization (FISH). However, FISH probes do not target only the annotated gene, while chromosome 17 (chr17) is among
Externí odkaz:
https://doaj.org/article/1c97f2dd901546c7920fc2c29acc59b9
Autor:
Anna Batistatou, Eleni Res, Christos Christodoulou, Natalia I Asimakopoulou, Jeff Sperinde, Georgios Oikonomopoulos, Dimitrios Bafaloukos, Georgios Rigakos, Elissavet Pazarli, George Fountzilas, Sofia Chrisafi, Dimitrios Pectasides, Pavlos Papakostas, Eleftheria Tsolaki, Georgia-Angeliki Koliou, Evangelia Razis, Angelos Koutras, Athanasios Kotsakis, Helen P. Kourea, George Zarkavelis
Publikováno v:
Anticancer research. 41(4)
Background/aim Human epidermal growth factor receptor 2 (HER2) P95-isoform could be involved in trastuzumab resistance in HER2 metastatic breast cancer. Materials and methods A total of 114 metastatic breast cancer patients treated with trastuzumab w
Autor:
George Pentheroudakis, Vassiliki Kotoula, Anastasia G Eleftheraki, Eleftheria Tsolaki, Ralph M Wirtz, Konstantine T Kalogeras, Anna Batistatou, Mattheos Bobos, Meletios A Dimopoulos, Eleni Timotheadou, Helen Gogas, Christos Christodoulou, Kyriaki Papadopoulou, Ioannis Efstratiou, Chrisoula D Scopa, Irene Papaspyrou, Dimitrios Vlachodimitropoulos, Helena Linardou, Epaminontas Samantas, Dimitrios Pectasides, Nicholas Pavlidis, George Fountzilas
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e70634 (2013)
BackgroundDiscrepant data have been published on the incidence and prognostic significance of ESR1 gene amplification in early breast cancer.Patients and methodsFormalin-fixed paraffin-embedded tumor blocks were collected from women with early breast
Externí odkaz:
https://doaj.org/article/de7b698a336a489a9dca63a420578ebb
Autor:
Eleftheria Tsolaki, Elsa Psoma, Konstantinos Markou, Vassiliki Kotoula, Dimitrios Pectasides, George Fountzilas, Sofia Chrisafi, Ioannis Tikas, Christina Bamia, Liliana Resiga, Eleni Giannoulatou, Elisabeta Ciuleanu, Mattheos Bobos, Kyriaki Papadopoulou, Anna Kalogera-Fountzila, Tudor Ciuleanu, Evangelos Giotakis, Kyriaki Manousou, Angelos Koutras, Maria Skondra, Amanda Psyrri, Thomas Zaramboukas, Dimitra Rontogianni
Publikováno v:
International Journal of Cancer. 142:66-80
Genomic patterns of nasopharyngeal carcinomas (NPC) have as yet been studied in Southeast Asian (SEA) patients. Here, we investigated genomic patterns of locally advanced NPC Southeast European (SEE) patients treated with chemo-radiotherapy. We exami
Autor:
Georgios Pentheroudakis, Flora Zagouri, George Kouvatseas, Ioannis Tikas, Eleftheria Tsolaki, Dimitrios Pectasides, Pavlos Papakostas, Christos Christodoulou, Angelos Koutras, Mattheos Bobos, G. Fountzilas, PA Kosmidis, Elpida Charalambous, Georgios Lazaridis, Vasiliki Kotoula, Eleni Giannoulatou, Ioannis Efstratiou
Publikováno v:
Cancer Research. 77:P6-09
Background-aim: HER2-positive breast cancer (BC) features high rates of tumor infiltrating lymphocytes (TILs) and mutations (mut) in various genes, more frequently in TP53. We investigated associations between TILs and mutations in HER2-positive BC a
Autor:
Anna Goussia, Ioannis Efstratiou, Triantafyllia Koletsa, Kitty Pavlakis, G. Fountzilas, Kalliopi Petraki, Maria Sotiropoulou, Helen Gogas, Zoi Alexopoulou, Georgios Pentheroudakis, Eleni Timotheadou, Eleftheria Tsolaki, Angelos Koutras, Anna Batistatou, Vasiliki Kotoula, E. Razis, Maria Karina, Mattheos Bobos
Publikováno v:
Cancer Research. 76:P5-08
Background-Aim: Breast cancer is a heterogeneous disease and despite recent scientific progress there is still need for the identification of biomarkers associated with risk for relapse, as well as for markers identifying patients who will benefit fr
Autor:
G. Raptou, Gerasimos Aravantinos, Pavlos Papakostas, Helen Gogas, Eleftheria Tsolaki, Vasiliki Kotoula, Ioannis Kostopoulos, Dimitris Bafaloukos, Kalliopi Petraki, Angelos Koutras, Amanda Psyrri, Konstantine T. Kalogeras, Elpida Charalambous, Georgios Pentheroudakis, Mattheos Bobos, Christos Christodoulou, G. Fountzilas, Ioannis Xanthakis, Zoi Alexopoulou, Dimitrios Pectasides
Publikováno v:
Cancer Research. 76:P4-14
Background-Aim: There is an unmet need for de-selecting HER2-positive patients with advanced breast cancer (ABC), since only some of those patients benefit from the addition of anti-HER2 agents to chemotherapy. The aim of this study was to investigat
Autor:
Ralph M. Wirtz, George Pentheroudakis, Elpida Charalambous, Flora Zagouri, Kyriaki Papadopoulou, Vassiliki Kotoula, Eleftheria Tsolaki, Eleni Timotheadou, Angelos Koutras, Sotiris Lakis, Zoi Alexopoulou, George Fountzilas, Aggeliki Lyberopoulou, Dimitrios Pectasides, Konstantine T. Kalogeras, Helen Gogas
Publikováno v:
Cancer Research. 75:P5-10
Background - Aim: Malignant tumors are currently understood as genetic mosaics. For breast cancer (BC) patient assessment, the challenge remains to use the increasingly available tumor genomic data along with standard clinicopathological parameters.