Zobrazeno 1 - 10
of 1 118
pro vyhledávání: '"Electrical Remodeling"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The compound NS5806 is a Kv4 channel modulator. This study investigated the chronic effects of NS5806 on cardiac hypertrophy induced by transverse aortic constriction (TAC) in mice in vivo and on neonatal rat ventricular cardiomyocyte hypert
Externí odkaz:
https://doaj.org/article/2953d5467b574c2aaa2c089310587c77
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-13 (2024)
Abstract Background Ubiquitin-specific protease 38 (USP38), belonging to the USP family, is recognized for its role in controlling protein degradation and diverse biological processes. Ventricular arrhythmias (VAs) following heart failure (HF) are cl
Externí odkaz:
https://doaj.org/article/c80bb67c75454533a1c4ef58b5312897
Autor:
Wuping Tan, Siyi Cheng, Qinfang Qiu, Jiaxing Huang, Mengjie Xie, Lingpeng Song, Zhen Zhou, Yijun Wang, Fuding Guo, Xiaoxing Jin, Zeyan Li, Xiao Xu, Hong Jiang, Xiaoya Zhou
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 117121- (2024)
Objectives: Celastrol has widespread therapeutic applications in various pathological conditions, including chronic inflammation. Previous studies have demonstrated the potent cardioprotective effects of celastrol. Nevertheless, limited attention has
Externí odkaz:
https://doaj.org/article/d9e1f2a286044f6baeb98f7a476d9be6
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 9 (2024)
Background Although moderate endurance exercise has been reported to improve cardiovascular health, its effects on cardiac structure and function are not fully characterized, especially with respect to sexual dimorphism. We aimed to assess the effect
Externí odkaz:
https://doaj.org/article/81be6f60bb1d4196bbe1ff2ecebfcce1
Autor:
Ozal Beylerli, Jiaming Ju, Aferin Beilerli, Ilgiz Gareev, Alina Shumadalova, Tatiana Ilyasova, Yunlong Bai, Baofeng Yang
Publikováno v:
Non-coding RNA Research, Vol 8, Iss 4, Pp 542-549 (2023)
Atrial fibrillation (AF) is a common cardiac arrhythmia that often occurs in patients with structural heart disease and is a significant cause of morbidity and mortality in clinical settings. AF is typically associated with significant changes of bot
Externí odkaz:
https://doaj.org/article/a45f34502a794addbbc333ce928aaf29
Autor:
Yanan Zhao, Praloy Chakraborty, Julianna Tomassetti, Tasnia Subha, Stéphane Massé, Paaladinesh Thavendiranathan, Filio Billia, Patrick F. H. Lai, Husam Abdel-Qadir, Kumaraswamy Nanthakumar
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 6207 (2024)
Cardiac arrhythmias remain a significant concern with Ibrutinib (IBR), a first-generation Bruton’s tyrosine kinase inhibitor (BTKi). Acalabrutinib (ABR), a next-generation BTKi, is associated with reduced atrial arrhythmia events. However, the role
Externí odkaz:
https://doaj.org/article/e1655ae973b84d528e9078e707000a43
Phloretin ameliorates heart function after myocardial infarction via NLRP3/Caspase-1/IL-1β signaling
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 165, Iss , Pp 115083- (2023)
Objectives/Aims: Inflammation is crucial in structural and electrical remodeling after myocardial infarction (MI), affecting cardiac pump function and conduction pathways. Phloretin possesses an anti-inflammation role by inhibiting the NLRP3/Caspase-
Externí odkaz:
https://doaj.org/article/fad2c92f4d524999a519ed78d65a5309
Autor:
Qiang Ye, Wen Chen, Hengsong Fu, Yanling Ding, Yuling Jing, Jingsong Shen, Ziyang Yuan, Kelan Zha
Publikováno v:
Reviews in Cardiovascular Medicine, Vol 24, Iss 10, p 288 (2023)
Atrial fibrillation (AF) is the most common type of arrhythmia in clinical practice, and its incidence is positively correlated with risk factors that include advanced age, hypertension, diabetes, and heart failure. Although our understanding of the
Externí odkaz:
https://doaj.org/article/98f3c3d74acb4147859a01aff00aeb69
Autor:
Jennifer Fumanelli, Silvia Garibaldi, Biagio Castaldi, Angela Di Candia, Alessandra Pizzuto, Domenico Sirico, Magdalena Cuman, Gianluca Mirizzi, Pietro Marchese, Massimiliano Cantinotti, Marcello Piacenti, Nadia Assanta, Cecilia Viacava, Giovanni Di Salvo, Giuseppe Santoro
Publikováno v:
Journal of Clinical Medicine, Vol 12, Iss 19, p 6334 (2023)
Background and aim: The GORE® CARDIOFORM (GCO) septal occluder is an atrial septal defect/patent foramen ovale closure device with theoretical advantages over other commercialized devices thanks to its softness and anatomical compliance. Our aim was
Externí odkaz:
https://doaj.org/article/1e611de7bbde4d0aa64cb1ad6287ee60
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