Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Eleanor Tuck"'
Autor:
Christy Hung, Eleanor Tuck, Victoria Stubbs, Sven J. van der Lee, Cora Aalfs, Resie van Spaendonk, Philip Scheltens, John Hardy, Henne Holstege, Frederick J. Livesey
Publikováno v:
Cell Reports, Vol 35, Iss 11, Pp 109259- (2021)
Summary: Dysfunction of the endolysosomal-autophagy network is emerging as an important pathogenic process in Alzheimer’s disease. Mutations in the sorting receptor-encoding gene SORL1 cause autosomal-dominant Alzheimer’s disease, and SORL1 varia
Externí odkaz:
https://doaj.org/article/2806293dc8bf440ca1a2cd951d19946a
Autor:
John Hardy, Sven J. van der Lee, Henne Holstege, Resie M. L. van Spaendonk, Frederick J. Livesey, Victoria Stubbs, Eleanor Tuck, Christy Hung, Cora Aalfs, Philip Scheltens
Publikováno v:
Hung, C, Tuck, E, Stubbs, V, van der Lee, S J, Aalfs, C, van Spaendonk, R, Scheltens, P, Hardy, J, Holstege, H & Livesey, F J 2021, ' SORL1 deficiency in human excitatory neurons causes APP-dependent defects in the endolysosome-autophagy network ', Cell Reports, vol. 35, no. 11, 109259 . https://doi.org/10.1016/j.celrep.2021.109259
Cell Reports
Cell Reports, 35(11):109259. Cell Press
Cell Reports, 35(11)
Cell Reports, Vol 35, Iss 11, Pp 109259-(2021)
Cell Reports
Cell Reports, 35(11):109259. Cell Press
Cell Reports, 35(11)
Cell Reports, Vol 35, Iss 11, Pp 109259-(2021)
Summary Dysfunction of the endolysosomal-autophagy network is emerging as an important pathogenic process in Alzheimer’s disease. Mutations in the sorting receptor-encoding gene SORL1 cause autosomal-dominant Alzheimer’s disease, and SORL1 varian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a58a569b76287149c22ec09d4a21d3cf
https://research.vumc.nl/en/publications/64053ab8-a8c5-4e83-b861-2630dac3aab8
https://research.vumc.nl/en/publications/64053ab8-a8c5-4e83-b861-2630dac3aab8
Publikováno v:
Cell Reports
Summary Directed differentiation of human pluripotent stem cells varies in specificity and efficiency. Stochastic, genetic, intracellular, and environmental factors affect maintenance of pluripotency and differentiation into early embryonic lineages.