Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Eleanor Smart"'
Autor:
Talveen S Purba, Kayumba Ng'andu, Lars Brunken, Eleanor Smart, Ellen Mitchell, Nashat Hassan, Aaron O'Brien, Charlotte Mellor, Jennifer Jackson, Asim Shahmalak, Ralf Paus
Publikováno v:
EMBO Molecular Medicine, Vol 11, Iss 10, Pp 1-16 (2019)
Abstract Taxanes are a leading cause of severe and often permanent chemotherapy‐induced alopecia. As the underlying pathobiology of taxane chemotherapy‐induced alopecia remains poorly understood, we investigated how paclitaxel and docetaxel damag
Externí odkaz:
https://doaj.org/article/90d9a44b6fc04a7aba33604064c0b735
Autor:
Iain S Haslam, Eleanor Smart
Publikováno v:
Biomarker Insights, Vol 14 (2019)
Damage to hair follicles following exposure to toxic chemotherapeutics can cause substantial hair loss, commonly known as chemotherapy-induced alopecia (CIA). Preventive therapies remain limited; however, recent advances in the use of scalp cooling t
Externí odkaz:
https://doaj.org/article/56b6855e945a47a29406d74e1e907006
Publikováno v:
Histochemistry and Cell Biology
Cholesterol has long been suspected of influencing hair biology, with dysregulated homeostasis implicated in several disorders of hair growth and cycling. Cholesterol transport proteins play a vital role in the control of cellular cholesterol levels
Autor:
Jennifer Jackson, Asim Shahmalak, Ellen Mitchell, Kayumba Ng'andu, Aaron O'Brien, Charlotte E L Mellor, Ralf Paus, Talveen S. Purba, Lars Brunken, Eleanor Smart, Nashat Hassan
Publikováno v:
EMBO Molecular Medicine, Vol 11, Iss 10, Pp n/a-n/a (2019)
EMBO Molecular Medicine
Purba, T, Ng'andu, K, Brunken, L, Lech, E, Mitchell, E, Hassan, N, O'Brien, A, Mellor, C, Jackson, J, Shahmalak, A & Paus, R 2019, ' CDK4/6 inhibition mitigates stem cell damage in a novel model for taxane-induced alopecia ', EMBO Molecular Medicine . https://doi.org/10.15252/emmm.201911031
EMBO Molecular Medicine
Purba, T, Ng'andu, K, Brunken, L, Lech, E, Mitchell, E, Hassan, N, O'Brien, A, Mellor, C, Jackson, J, Shahmalak, A & Paus, R 2019, ' CDK4/6 inhibition mitigates stem cell damage in a novel model for taxane-induced alopecia ', EMBO Molecular Medicine . https://doi.org/10.15252/emmm.201911031
Taxanes are a leading cause of severe and often permanent chemotherapy‐induced alopecia. As the underlying pathobiology of taxane chemotherapy‐induced alopecia remains poorly understood, we investigated how paclitaxel and docetaxel damage human s
Autor:
Yong Jian Zhou, Xu Teng, David Rutkowski, Gui Xuan Zhou, Iain S. Haslam, Zhicao Yue, Xiu Lan Ao, Bessam Farjo, Zhen Huang, Eleanor Smart, Yan Ding Zhang, Ralf Paus, Guo Jiang Xie, Zhi Peng Yan, Justyna Wierzbicka, Nilofer Farjo
Publikováno v:
The Journal of investigative dermatology. 141(2)
Chemotherapy-induced hair loss (alopecia) (CIA) remains a major unsolved problem in clinical oncology. CIA is often considered to be a consequence of the antimitotic and apoptosis-promoting properties of chemotherapy drugs acting on rapidly prolifera
Autor:
Xiulan Ao, Xu Teng, YongJian Zhou, Iain S. Haslam, YanDing Zhang, Guojiang Xie, Guixuan Zhou, Justyna Wierzbicka, Nilofer Farjo, Zhen Huang, Bessam Farjo, Zhicao Yue, Zhipeng Yan, David Rutkowski, Ralf Paus, Eleanor Smart
Publikováno v:
Journal of Investigative Dermatology. 140:B16
Chemotherapy-induced hair loss (alopecia, CIA) remains a major unsolved problem in clinical oncology. CIA is often considered to be a consequence of the anti-mitotic and apoptosis-promoting properties of chemotherapy drugs acting on rapidly prolifera
Autor:
Francisco Jimenez, C. I. Platt, Eleanor Smart, Enrique Poblet, Ralf Paus, Irene Hernandez, M. Alam, Jonathan A. Hardman, Marta Bertolini
Publikováno v:
Hernandez, I, Alam, M, Platt, C, Hardman, J, Smart, E, Poblet, E, Bertolini, M, Paus, R & Jimenez, F 2018, ' A technique for more precise distinction between catagen and telogen human hair follicles ex-vivo ', Journal of the American Academy of Dermatology, vol. 79, no. 3 . https://doi.org/10.1016/j.jaad.2018.02.009