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pro vyhledávání: '"Eleanor S, Drummond"'
Autor:
Eleanor S Drummond, Jill Muhling, Ralph N Martins, Linda K Wijaya, Erich M Ehlert, Alan R Harvey
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59166 (2013)
Accumulation of beta amyloid (Aβ) in the brain is a primary feature of Alzheimer's disease (AD) but the exact molecular mechanisms by which Aβ exerts its toxic actions are not yet entirely clear. We documented pathological changes 3 and 6 months af
Externí odkaz:
https://doaj.org/article/dbf41251c8764877b14f27b03debed5c
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31061 (2012)
Recombinant adeno-associated viral (rAAV) vectors can be used to introduce neurotrophic genes into injured CNS neurons, promoting survival and axonal regeneration. Gene therapy holds much promise for the treatment of neurotrauma and neurodegenerative
Externí odkaz:
https://doaj.org/article/841891a662834f61a138ce88a7a6f469
Autor:
Alan R, Harvey, Erich, Ehlert, Joris, de Wit, Eleanor S, Drummond, Margaret A, Pollett, Marc, Ruitenberg, Giles W, Plant, Joost, Verhaagen, Christiaan N, Levelt
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 515
We here describe various approaches using GFP that are being used in the morphological and functional analysis of specific cell types in the normal and injured central nervous system. Incorporation of GFP into viral vectors allows phenotypic characte