Zobrazeno 1 - 10
of 192
pro vyhledávání: '"Eleanor M. Scott"'
Autor:
Tara TM Lee, Corinne Collett, Simon Bergford, Sara Hartnell, Eleanor M Scott, Robert S Lindsay, Katharine F Hunt, David R McCance, Katharine Barnard-Kelly, David Rankin, Julia Lawton, Rebecca M Reynolds, Emma Flanagan, Matthew Hammond, Lee Shepstone, Malgorzata E Wilinska, Judy Sibayan, Craig Kollman, Roy Beck, Roman Hovorka, Helen R Murphy
Publikováno v:
Efficacy and Mechanism Evaluation, Vol 11, Iss 07 (2024)
Background There are over 2000 pregnancies annually in women with type 1 diabetes in the UK. Despite recent improvements in diabetes technology, most women cannot achieve and maintain the recommended pregnancy glucose targets. Thus, one in two babies
Externí odkaz:
https://doaj.org/article/5caaa7797e3e45e586f75d15a79334a5
Autor:
Eleanor M Scott, Helen R. Murphy, Jenny Myers, Ponnusamy Saravanan, Lucilla Poston, Graham R Law
Publikováno v:
BMC Pregnancy and Childbirth, Vol 23, Iss 1, Pp 1-6 (2023)
Abstract Background Continuous glucose monitoring (CGM) provides the most objective method of assessing glucose in daily life. Although there have been small, short-term physiologic studies of glucose metabolism in ‘healthy’ pregnant women a comp
Externí odkaz:
https://doaj.org/article/9a76b5c327fd40b8836422eca3a7bf1b
Autor:
Tara T. M. Lee, Corinne Collett, Mei-See Man, Matt Hammond, Lee Shepstone, Sara Hartnell, Eleanor Gurnell, Caroline Byrne, Eleanor M. Scott, Robert S. Lindsay, Damian Morris, Anna Brackenridge, Anna R. Dover, Rebecca M. Reynolds, Katharine F. Hunt, David R. McCance, Katharine Barnard-Kelly, David Rankin, Julia Lawton, Laura E. Bocchino, Judy Sibayan, Craig Kollman, Malgorzata E. Wilinska, Roman Hovorka, Helen R. Murphy, on behalf of the AiDAPT Collaborative Group
Publikováno v:
BMC Pregnancy and Childbirth, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Pregnant women with type 1 diabetes strive for tight glucose targets (3.5-7.8 mmol/L) to minimise the risks of obstetric and neonatal complications. Despite using diabetes technologies including continuous glucose monitoring (CGM)
Externí odkaz:
https://doaj.org/article/1040a294e4914043b9de266ca4e070a9
Autor:
Michael A Zulyniak, Naomi S Clement, Eleanor M Scott, Cassy F Dingena, Anvesha Mahendra, Melvin J Holmes
Publikováno v:
BMJ Open, Vol 13, Iss 2 (2023)
Introduction Diabetes in pregnancy presents a unique physiological challenge to manage glycaemia while maintaining adequate nourishment for the growing fetus. Women with diabetes who become pregnant are at greater risk of adverse maternal and newborn
Externí odkaz:
https://doaj.org/article/3411c7c05bde4c2ebd0d573afe93138d
Autor:
Cassy F. Dingena, Melvin J. Holmes, Matthew D. Campbell, Janet E. Cade, Eleanor M. Scott, Michael A. Zulyniak
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
ObjectivesStudies that use continuous glucose monitoring (CGM) to monitor women with gestational diabetes (GDM), highlight the importance of managing dysglycemia over a 24-hour period. However, the effect of current treatment methods on dysglycemia o
Externí odkaz:
https://doaj.org/article/ac1c3e61c6c34fa2a06dc472a8698bfc
Autor:
Cassy F. Dingena, Daria Arofikina, Matthew D. Campbell, Melvin J. Holmes, Eleanor M. Scott, Michael A. Zulyniak
Publikováno v:
Nutrients, Vol 15, Iss 2, p 323 (2023)
Diabetes disrupts one in six pregnancies, bestowing immediate and long-term health risks to mother and child. Diet and exercise are commonly prescribed to control dysglycemia, but their effectiveness across sub-populations and types of diabetes (type
Externí odkaz:
https://doaj.org/article/fa63407820434e6690542f45a4f90eff
Autor:
Eleanor M. Scott, Egon J. Jacobus, Brian Lyons, Sally Frost, Joshua D. Freedman, Arthur Dyer, Hena Khalique, William K. Taverner, Alison Carr, Brian R. Champion, Kerry D. Fisher, Len W. Seymour, Margaret R. Duffy
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-18 (2019)
Abstract Background Tumour-associated macrophages (TAMs) are often implicated in cancer progression but can also exert anti-tumour activities. Selective eradication of cancer-promoting (M2-like) TAM subsets is a highly sought-after goal. Here, we hav
Externí odkaz:
https://doaj.org/article/d5fee97270fd469da9e2aa78cc47e661
Autor:
Hena Khalique, Richard Baugh, Arthur Dyer, Eleanor M. Scott, Sally Frost, Sarah Larkin, Janet Lei-Rossmann, Leonard W. Seymour
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 4 (2021)
Background Programmed death-ligand 1 (PD-L1) is an important immune checkpoint protein that can be regarded as a pan-cancer antigen expressed by multiple different cell types within the tumor. While antagonizing PD-L1 is well known to relieve PD-1/PD
Externí odkaz:
https://doaj.org/article/6903c64ec4004e1ea2bd2210441945da
Autor:
Joshua D Freedman, Joachim Hagel, Eleanor M Scott, Ioannis Psallidas, Avinash Gupta, Laura Spiers, Paul Miller, Nikolaos Kanellakis, Rebecca Ashfield, Kerry D Fisher, Margaret R Duffy, Leonard W Seymour
Publikováno v:
EMBO Molecular Medicine, Vol 9, Iss 8, Pp 1067-1087 (2017)
Abstract Oncolytic viruses exploit the cancer cell phenotype to complete their lytic life cycle, releasing progeny virus to infect nearby cells and repeat the process. We modified the oncolytic group B adenovirus EnAdenotucirev (EnAd) to express a bi
Externí odkaz:
https://doaj.org/article/65cb8311f33a4664948ad2d02957a40c
Autor:
Kerry D. Fisher, Leonard W. Seymour, Brian R. Champion, Paul Miller, Adam Lambert, Clare Verrill, Richard J. Bryant, Leticia Campo, Joachim Hagel, Eleanor M. Scott, Alice Muntzer, Janet Lei-Rossmann, Margaret R. Duffy, Joshua D. Freedman
Supplementary Files detailing additional experiments supporting the conclusions of the manuscript, including additional activation, cytotoxicity, and cytokine analyses. Supplementary tables contain more details on characterisation of patient biopsies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::485e705c7efbfb716257f1d09ff10e04
https://doi.org/10.1158/0008-5472.22419483
https://doi.org/10.1158/0008-5472.22419483
