Výsledky vyhledávání - "Eleanor Lynam"

Akademický článek

Neutrophil breaching of the blood vessel pericyte layer during diapedesis requires mast cell-derived IL-17A

Autor: Régis Joulia, Idaira María Guerrero-Fonseca, Tamara Girbl, Jonathon A. Coates, Monja Stein, Laura Vázquez-Martínez, Eleanor Lynam, James Whiteford, Michael Schnoor, David Voehringer, Axel Roers, Sussan Nourshargh, Mathieu-Benoit Voisin

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)

The blood vessel wall is a complex multi-layered structure, yet upon injury or infection, neutrophil leukocytes are rapidly migrating from the blood stream to the affected tissues, by a process termed diapedesis. Authors here show that the final step

Externí odkaz: https://doaj.org/article/84b97690afca49fa86cbd85337ff0f72

Zobrazit plný text záznamu

Context-dependent regulation of endothelial cell metabolism:differential effects of the PPARβ/δ agonist GW0742 and VEGF-A

Autor: Caroline P.D. Wheeler-Jones, Nicole Wagner, Ashton Faulkner, Coleen Jones, Mary Board, Kay-Dietrich Wagner, Eleanor Lynam, Carolyn A. Carr, Colleen Lopez, Robert Purcell

Publikováno v: Faulkner, A R M, Lynam, E, Purcell, R, Jones, C, Lopez, C, Board, M, Wagner, K, Wagner, N, Carr, C & Wheeler-Jones, C 2020, ' Context-dependent regulation of endothelial cell metabolism : differential effects of the PPARβ/δ agonist GW0742 and VEGF-A ', Scientific Reports, vol. 10, no. 1, 7849 (2020) . https://doi.org/10.1038/s41598-020-63900-0
Scientific Reports
Scientific Reports, 2020, 10 (1), pp.7849. ⟨10.1038/s41598-020-63900-0⟩
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.7849. ⟨10.1038/s41598-020-63900-0⟩
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)

Peroxisome proliferator activated receptor β/δ (PPARβ/δ) has pro-angiogenic functions, but whether PPARβ/δ modulates endothelial cell metabolism to support the dynamic phenotype remains to be established. This study characterised the metabolic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a48869a050350e5ba1b5affb184e1660
https://research-information.bris.ac.uk/en/publications/b4dea565-22da-4c68-ba66-a60406451ccb

Zobrazit plný text záznamu

Distinct Compartmentalization of the Chemokines CXCL1 and CXCL2 and the Atypical Receptor ACKR1 Determine Discrete Stages of Neutrophil Diapedesis

Autor: Sussan Nourshargh, Anna Barkaway, Gerard J. Graham, Ronen Alon, Antal Rot, Carlos del Fresno, Tamara Girbl, David Sancho, Eleanor Lynam, Aude Thiriot, Loïc Rolas, Marcus Thelen, Mathieu-Benoit Voisin, Lorena Perez, Tchern Lenn, Elin Hub, Ulrich H. von Andrian

Publikováno v: Repisalud
Instituto de Salud Carlos III (ISCIII)
Immunity

Neutrophils require directional cues to navigate through the complex structure of venular walls and into inflamed tissues. Here we applied confocal intravital microscopy to analyze neutrophil emigration in cytokine-stimulated mouse cremaster muscles.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c41885fa03ecaa783b0e12c14e6561cf
http://hdl.handle.net/20.500.12105/7143

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání