Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Eleanor Kuntz"'
Autor:
Yuka Yamaguchi, Mark Gimbel, Ann Forslund, Zhaoshi Zeng, Chin-Tung Chen, Matthew D’Alessio, Sajid A. Khan, Eleanor Kuntz, Philip B. Paty, Alfred T. Culliford, Martin R. Weiser, Garrett M. Nash, Francis Barany
Publikováno v:
Cancer Letters. 265:258-269
The c-Met proto-oncogene encodes a receptor tyrosine kinase (TK) that promotes invasive tumor growth and metastasis. Recent studies show that the presence of c-Met gene amplification is predictive for selective c-Met TK inhibitors in gastric cancer a
Autor:
Mark Y. Sun, Martin R. Weiser, Todd D. Francone, Chin-Tung Chen, Ron G. Landmann, Philip B. Paty, Zhaoshi Zeng, Ronald P. DeMatteo, Eleanor Kuntz
Publikováno v:
Molecular cancer therapeutics. 6(4)
c-Met, a receptor tyrosine kinase responsible for cellular migration, invasion, and proliferation, is overexpressed in human cancers. Although ligand-independent c-Met activation has been described, the majority of tumors are ligand dependent and rel
Autor:
Jinru Shia, Todd D. Francone, Ron G. Landmann, Martin R. Weiser, Eleanor Kuntz, Philip B. Paty, Zhaoshi Zeng, Udai S. Kammula
Publikováno v:
Cancer letters. 248(2)
Introduction/hypothesis Over-expression of the c-Met receptor tyrosine kinase has been described in a variety of cancers and implicated in tumor progression. Unlike some solid tumors, current evidence indicates that c-Met activation in colon cancer i
Autor:
Todd D. Francone, Chin-Tung Chen, Martin R. Weiser, Eleanor Kuntz, Philip B. Paty, Zaoshi Zeng, Ron G. Landmann
Publikováno v:
Journal of the American College of Surgeons. 203:S88
METHODS: In 63 patients with CRC liver metastases, we quantified MET mRNA from microdissected tumor and adjacent normal liver by Real-Time RT-PCR. Using random primed cDNA and genespecific PCR, specimen threshold cycle was determined and standard cur
Autor:
Ron G. Landmann, Udai S. Kammula, Martin R. Weiser, Jinru Shia, Eleanor Kuntz, Philip B. Paty, Zhaoshi Zeng
Publikováno v:
Journal of the American College of Surgeons. 199:90
Introduction: MET, a receptor tyrosine kinase, and its ligand, hepatocyte growth factor (HGF), are critical in cellular proliferation, motility, and invasion. We hypothesize that elevated MET and HGF gene expression predicts metastatic spread and poo