Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Eleanor J Ward"'
Autor:
David Coe, Thanushiyan Poobalasingam, Hongmei Fu, Fabrizia Bonacina, Guosu Wang, Valle Morales, Annalisa Moregola, Nico Mitro, Kenneth C.P. Cheung, Eleanor J. Ward, Suchita Nadkarni, Dunja Aksentijevic, Katiuscia Bianchi, Giuseppe Danilo Norata, Melania Capasso, Federica M. Marelli-Berg
Publikováno v:
JCI Insight, Vol 7, Iss 10 (2022)
Voltage-gated hydrogen channel 1 (Hvcn1) is a voltage-gated proton channel, which reduces cytosol acidification and facilitates the production of ROS. The increased expression of this channel in some cancers has led to proposing Hvcn1 antagonists as
Externí odkaz:
https://doaj.org/article/a22c09e639a14cbb8d7cc29fcaebece0
Autor:
Eleanor J. Ward, Serena Bert, Silvia Fanti, Kerri M. Malone, Robert T. Maughan, Christina Gkantsinikoudi, Fabrice Prin, Lia Karina Volpato, Anna Paula Piovezan, Gerard J. Graham, Neil P. Dufton, Mauro Perretti, Federica M. Marelli-Berg, Suchita Nadkarni
Publikováno v:
Circulation.
Background: Placental heart development and embryonic heart development occur in parallel, and these organs have been proposed to exert reciprocal regulation during gestation. Poor placentation has been associated with congenital heart disease, an im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4c83a4fc274bd2ecb2820d9a84bc377
https://pubmed.ncbi.nlm.nih.gov/36484244
https://pubmed.ncbi.nlm.nih.gov/36484244
Autor:
Elli Papaemmanuil, Amy A Kirkwood, Andrew McMillan, Eleanor J. Ward, David I. Marks, Amir Enshaei, Claire Schwab, Daniel Leongamornlert, Pip Patrick, Ellie Butler, Emilio Barretta, Christine J. Harrison, Clare J. Rowntree, Laura Clifton-Hadley, Tom Creasey, Bela Patel, Adele K. Fielding, Anthony V. Moorman, Tobias Menne, Katie Twentyman
Publikováno v:
Leukemia. 36:625-636
Chromosomal abnormalities are established prognostic markers in adult ALL. We assessed the prognostic impact of established chromosomal abnormalities and key copy number alterations (CNA) among 652 patients with B-cell precursor ALL treated on a mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aee3123b8bff4e24fbc3128c92fc684b
https://doi.org/10.1038/s41375-021-01448-2
https://doi.org/10.1038/s41375-021-01448-2
Publikováno v:
Immunology
The immunology of pregnancy has been the focus of many studies to better understand how the mother is able to tolerate the presence of a semi‐allogeneic fetus. Far from the initial view of pregnancy as a state of immunosuppression, successful fetal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82fedcba0808cf05d8c2fbd32ceee9e8
https://doi.org/10.1111/imm.13392
https://doi.org/10.1111/imm.13392
Autor:
Eleanor J Ward, Serena Bert, Silvia Fanti, Neil P Dufton, Kerri M Malone, Robert T Maughan, Fabrice Prin, Lia Karina Volpato, Anna Paula Piovezan, Mauro Perretti, Federica M Marelli-Berg, Suchita Nadkarni
Placental and embryonic heart development occurs in parallel, and these organs have been proposed to exert reciprocal regulation during gestation. Poor placentation has been associated with congenital heart disease (CHD), an important cause of infant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48a7c9c0ddf1be0a237a3bae24b20e1f
https://doi.org/10.1101/2022.03.10.482611
https://doi.org/10.1101/2022.03.10.482611
Autor:
Lamya Yamani, Frances R. Balkwill, Federica M. Marelli-Berg, Juho Vuononvirta, Melania Capasso, Eleanor J. Ward, Suchita Nadkarni, Maryam Jangani
Publikováno v:
Journal of leukocyte biology 111(5), 967-980 (2022). doi:10.1002/JLB.1A0920-588R
Monocyte migration to the sites of inflammation and maturation into macrophages are key steps for their immune effector function. Here, we show that mechanistic target of rapamycin complex 2 (mTORC2)-dependent Akt activation is instrumental for metab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c37bac8cd8d674c7b85b94c49a2a57
https://pub.dzne.de/record/162927
https://pub.dzne.de/record/162927
Autor:
Anthony V, Moorman, Emilio, Barretta, Ellie R, Butler, Eleanor J, Ward, Katie, Twentyman, Amy A, Kirkwood, Amir, Enshaei, Claire, Schwab, Tom, Creasey, Daniel, Leongamornlert, Elli, Papaemmanuil, Pip, Patrick, Laura, Clifton-Hadley, Bela, Patel, Tobias, Menne, Andrew K, McMillan, Christine J, Harrison, Clare J, Rowntree, David I, Marks, Adele K, Fielding
Publikováno v:
Leukemia. 36(3)
Chromosomal abnormalities are established prognostic markers in adult ALL. We assessed the prognostic impact of established chromosomal abnormalities and key copy number alterations (CNA) among 652 patients with B-cell precursor ALL treated on a mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a8d49eb7fc529ac0c3e751d3d48faf70
https://pubmed.ncbi.nlm.nih.gov/34657128
https://pubmed.ncbi.nlm.nih.gov/34657128
Autor:
Oliver Zaccheo, Hanna Hailu, Shirley Jane Peters, Frank R. Brennan, Eleanor J. Ward, Rona M. Cutler, Andrew M. Ventom, Nicola L. Davies, David P. Humphreys, Farnaz Fallah-Arani, Thomas L. Pither, Tania F. Rowley, Gianluca Fossati, Louise J. Healy, Joshua M. Sopp, Mike Aylott, Katharine Cain, Alison Eddleston, John Sherington, Robert J. Griffin
Publikováno v:
Communications Biology, Vol 1, Iss 1, Pp 1-12 (2018)
Autoantibody-mediated diseases are currently treated with intravenous immunoglobulin, which is thought to act in part via blockade of Fc gamma receptors, thereby inhibiting autoantibody effector functions and subsequent pathology. We aimed to develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5549f806a17d958b41fae45c108dfc14
http://link.springer.com/article/10.1038/s42003-018-0149-9
http://link.springer.com/article/10.1038/s42003-018-0149-9
Publikováno v:
Cellular and Molecular Life Sciences
Protective immunity relies upon T cell differentiation and subsequent migration to target tissues. Similarly, immune homeostasis requires the localization of regulatory T cells (Tregs) to the sites where immunity takes place. While naïve T lymphocyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0838339351491b87bd60c71dfd1b47c4
https://doi.org/10.1007/s00018-016-2211-4
https://doi.org/10.1007/s00018-016-2211-4