Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Eleanor C. Weir"'
Autor:
Andrew F. Stewart, Arthur E. Broadus, Karl L. Insogna, Eleanor C. Weir, Terence Wu, William J. Burtis
Publikováno v:
Journal of Bone and Mineral Research. 2:37-43
Three bioassays are widely employed for the measurement of PTH-like adenylate cyclase-stimulating factors (ACSFs) drived from tumors associated with humoral hypercalcemia of malignancy. These include renal cortical adenylate cyclase (RAC) assays, rat
Autor:
Eleanor C. Weir, Michael Centrella, Roland Baron, Karl L. Insogna, Mark C. Horowitz, Barry M. Kacinski
Publikováno v:
Journal of Bone and Mineral Research. 8:1507-1518
Colony-stimulating factors (CSF) may play a role in bone resorption. To examine whether osteoblasts secrete colony-stimulating activity (CSA) in response to parathyroid hormone (PTH) and parathyroid hormone-related peptide (PTHrP), conditioned medium
Autor:
Roland Baron, Eleanor C. Weir, Arthur E. Broadus, William M. Philbrick, Lynn Neff, Michael Amling
Publikováno v:
Proceedings of the National Academy of Sciences. 93:10240-10245
Parathyroid hormone-related peptide (PTHrP) was initially identified as a product of malignant tumors that mediates paraneoplastic hypercalcemia. It is now known that the parathyroid hormone (PTH) and PTHrP genes are evolutionarily related and that t
Publikováno v:
Journal of Cellular Physiology. 168:199-208
Tumor necrosis factor-alpha (TNF-alpha) stimulates bone resorption both in vitro and in vivo. The cellular mechanisms for this effect are not known but one pathway may be via release of osteoblast derived factors which stimulate osteoclast formation.
Autor:
Romana Angelika Nowak, Eleanor C. Weir, Dale L. Goad, William J. Burtis, Barbara E. Dreyer, Anastasia G. Daifotis
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 78:784-789
Uterine leiomyomas or fibroids are common among women of reproductive age, but their biology is poorly understood. The PTH-related protein (PTHrP) has been identified in a number of sites throughout the reproductive tract. We, therefore, examined whe
Publikováno v:
Journal of Biological Chemistry. 267:23455-23458
We previously observed a peak in parathyroid hormone-related peptide (PTHrP) mRNA expression in preterm rat myometrium and found that this peak was dependent on intrauterine occupancy. We explored the possibility that mechanotransduction might contro
Publikováno v:
Calcified Tissue International. 51:30-34
Parathyroid hormone-related protein (PTHRP) has recently been purified from human tumors associated with the syndrome of humoral hypercalcemia of malignancy. The gene encoding PTHRP has been cloned, and based on predicted amino acid sequence, polypep
Publikováno v:
Endocrinology. 141(8)
Colony-stimulating factor (CSF)-1 is a hematopoietic growth factor that is released by osteoblasts and is recognized to play a critical role in bone remodeling in vivo and in vitro. We have reported that osteoblasts express CSF-1 constitutively and t
Autor:
Eleanor C. Weir, Elizabeth Spencer, Ben-hua Sun, Mark C. Horowitz, Karl L. Insogna, Gang-Qing Yao, Elizabeth E. Hammond
Publikováno v:
The Journal of biological chemistry. 273(7)
Colony-stimulating factor-1 (CSF-1) is a hematopoietic growth factor that is released by osteoblasts and is recognized to play a critical role in bone remodeling in vivo and in vitro. CSF-1 is synthesized as a soluble or cell-surface protein. It is u
Autor:
Roland Baron, Eleanor C. Weir, Michael Amling, Lynn Neff, Keisuke Kuida, Sakae Tanaka, Arthur E. Broadus, William M. Philbrick, Daisuke Inoue
Publikováno v:
The Journal of Cell Biology
Parathyroid hormone–related peptide (PTHrP) appears to play a major role in skeletal development. Targeted disruption of the PTHrP gene in mice causes skeletal dysplasia with accelerated chondrocyte maturation (Amizuka, N., H. Warshawsky, J.E. Hend