Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Eleanor Browne"'
Autor:
Rachel E. James, Renee Schalks, Eleanor Browne, Ioanna Eleftheriadou, Carmen Picon Munoz, Nicholas D. Mazarakis, Richard Reynolds
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-18 (2020)
Abstract Analysis of isolated meninges and cerebrospinal fluid (CSF) of post-mortem MS cases has shown increased gene and protein expression for the pro-inflammatory cytokines: tumour necrosis factor (TNF) and interferon-γ (IFNγ). Here we tested th
Externí odkaz:
https://doaj.org/article/79329206a253482996306a228b798294
Autor:
Patricia Gallego-Delgado, Rachel James, Eleanor Browne, Joanna Meng, Swetha Umashankar, Li Tan, Carmen Picon, Nicholas D Mazarakis, A Aldo Faisal, Owain W Howell, Richard Reynolds
Publikováno v:
PLoS Biology, Vol 18, Iss 12, p e3001008 (2020)
Changes to the structure of nodes of Ranvier in the normal-appearing white matter (NAWM) of multiple sclerosis (MS) brains are associated with chronic inflammation. We show that the paranodal domains in MS NAWM are longer on average than control, wit
Externí odkaz:
https://doaj.org/article/af2cd0c7ca3a4e8d88ba7f3fe0e37a65
Autor:
Emily Matthews, Thomas Bannan, M. Anwar Khan, Dudley Shallcross, Harald Stark, Eleanor Browne, Alexander Archibald, Stéphane Bauguitte, Chris Reed, Navaneeth Thamban, Huihui Wu, James Lee, Lucy Carpenter, Ming-xi Yang, Thomas Bell, Grant Allen, Carl Percival, Gordon McFiggans, Martin Gallagher, Hugh Coe
Despite the reduced nitrogen (N) cycle being central to global biogeochemistry, there are large uncertainties surrounding its sources and rate of cycling. Here, we present the first observations of gas-phase urea (CO(NH₂)₂) in the atmosphere from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d342a9b855d0170b763830df5baf48f5
https://doi.org/10.5194/egusphere-egu23-6620
https://doi.org/10.5194/egusphere-egu23-6620
Autor:
Rachel E James Bates, Eleanor Browne, Renee Schalks, Heather Jacobs, Li Tan, Puja Parekh, Roberta Magliozzi, Massimiliano Calabrese, Nicholas D Mazarakis, Richard Reynolds
Publikováno v:
Brain. 145:4287-4307
Organized meningeal immune cell infiltrates are suggested to play an important role in cortical grey matter pathology in the multiple sclerosis brain, but the mechanisms involved are as yet unresolved. Lymphotoxin-alpha plays a key role in lymphoid o
Autor:
Eleanor Browne, Mitchell Alton
Publikováno v:
ACS Environmental Au. 2:263-274
Autor:
Nicholas D. Mazarakis, Massimiliano Calabrese, Schalks R, Lionel Tan, Jacobs H, Roberta Magliozzi, James Bates Re, Richard Reynolds, Parekh P, Eleanor Browne
Lymphotoxin alpha (LTα) plays an important role in lymphoid organ development and cellular cytotoxicity in the immune system. LTα expression is increased in the cerebrospinal fluid of naïve and progressive multiple sclerosis (MS) patients and post
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e4b5e44cb5a95f318e13a6930939443
https://doi.org/10.1101/2021.04.27.441396
https://doi.org/10.1101/2021.04.27.441396
Autor:
Swetha Umashankar, Richard Reynolds, Carmen Picón, Nicholas D. Mazarakis, Rachel James, Joanna Meng, Patricia Gallego, Eleanor Browne, Owain W. Howell, A. Aldo Faisal
Changes to the structure of nodes of Ranvier in the normal-appearing white matter (NAWM) of MS brains are associated with chronic inflammation. We show that the paranodal domains in MS NAWM are longer on average than control, with Kv1.2 channels disl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ace7a3f83f6167bee084ebd22d34b495
https://doi.org/10.1101/2020.06.10.142281
https://doi.org/10.1101/2020.06.10.142281
Autor:
Richard Reynolds, Rachel E. James, Ioanna Eleftheriadou, Carmen Picon Munoz, Nicholas D. Mazarakis, Renee Schalks, Eleanor Browne
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-18 (2020)
Acta Neuropathologica Communications
Acta Neuropathologica Communications
Analysis of isolated meninges and cerebrospinal fluid (CSF) of post-mortem MS cases has shown increased gene and protein expression for the pro-inflammatory cytokines: tumour necrosis factor (TNF) and interferon-γ (IFNγ). Here we tested the hypothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eab17103a92250ac39d30e24ecc110d
http://hdl.handle.net/10044/1/79273
http://hdl.handle.net/10044/1/79273