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pro vyhledávání: '"Eleanor Blair Towers"'
Autor:
Eleanor Blair Towers, Ivy L. Williams, Ariadne S. K. Aristidou, Ajibike O. Salako-Akande, Wendy J. Lynch
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Relapse to drug use after abstinence is a major challenge in treating substance use disorder. Exposure to drug-associated cues during abstinence can trigger intense craving and precipitate relapse. New and more effective anti-relapse interve
Externí odkaz:
https://doaj.org/article/c3e66a772f5d431c98dffba88422e144
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
A hallmark of cocaine use disorder (CUD) is dysfunction of dopamine signaling in the mesolimbic pathway, including impaired dopamine 2 (D2) receptor signaling. One of the most replicated findings in human imagining studies is decreased striatal D2 re
Externí odkaz:
https://doaj.org/article/4ed6e9ba7a4049c0af3d148f7f6ad72c
Autor:
Eleanor Blair Towers, Madison Kilgore, Anousheh Bakhti-Suroosh, Lasyapriya Pidaparthi, Ivy L. Williams, Jean M. Abel, Wendy J. Lynch
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2023)
IntroductionWomen have a shorter course from initial cocaine use to meeting the criteria for cocaine use disorder as compared to men. Preclinical findings similarly indicate that females develop key features of an addiction-like phenotype faster than
Externí odkaz:
https://doaj.org/article/69d26b09bfc84539ab12c1dfee2c2fa4
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Opioid use disorder (OUD) is a major epidemic in the United States, and fentanyl is a major culprit. The National Institute on Drug Abuse has highlighted an urgent need for research on the risks and outcomes of OUD with fentanyl; a better understandi
Externí odkaz:
https://doaj.org/article/d429e239c48b490d8f605deb86a41e3e
Publikováno v:
Pharmacological Reviews. 75:217-249
Publikováno v:
Neuroendocrinology.
Rationale: Women are more vulnerable than men in many aspects of opioid use disorder (OUD); a major theory of sex differences in substance use disorders is that these differences are due to ovarian hormones with estradiol enhancing vulnerability in f
Autor:
Eleanor Blair Towers, Daniel A. Shapiro, Jean M. Abel, Anousheh Bakhti-Suroosh, Kristyna Kupkova, David T. Auble, Patrick A. Grant, Wendy J. Lynch
Publikováno v:
Biological Psychiatry Global Open Science.
Publikováno v:
Psychopharmacology (Berl)
RATIONALE: Women meet criteria for substance use disorder after fewer years of drug use than men; this accelerated time-course, or telescoping effect, has been observed for multiple drugs, including cocaine. Preclinical findings similarly indicate an
Publikováno v:
Psychopharmacology
Rationale Opioid use disorder (OUD) is a major epidemic in the USA. Despite evidence indicating that OUD may be particularly severe for women, preclinical models have yet to establish sex as a major factor in OUD. Objectives Here, we examined sex dif
Publikováno v:
Frontiers in pharmacology. 13
Opioid use disorder (OUD) is a major epidemic in the United States, and fentanyl is a major culprit. The National Institute on Drug Abuse has highlighted an urgent need for research on the risks and outcomes of OUD with fentanyl; a better understandi