Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Eleanor A. Fallon"'
Autor:
Emily Hensler, Habesha Petros, Chyna C. Gray, Chun-Shiang Chung, Alfred Ayala, Eleanor A. Fallon
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Sepsis, a dysfunctional immune response to infection leading to life-threatening organ injury, represents a significant global health issue. Neonatal sepsis is disproportionately prevalent and has a cost burden of 2-3 times that of adult patients. De
Externí odkaz:
https://doaj.org/article/353ef0331d194705b0ed586a247e6c58
Autor:
Eleanor A. Fallon, Chun-Shiang Chung, Daithi S. Heffernan, Yaping Chen, Monique E. De Paepe, Alfred Ayala
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Morbidity and mortality associated with neonatal sepsis remains a healthcare crisis. PD1−/− neonatal mice endured experimental sepsis, in the form of cecal slurry (CS), and showed improved rates of survival compared to wildtype (WT) counterparts.
Externí odkaz:
https://doaj.org/article/d6f68774959d4b8195af7648979470f4
Autor:
Eleanor A. Fallon, Tristen T. Chun, Whitney A. Young, Chyna Gray, Alfred Ayala, Daithi S. Heffernan
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
We have shown that invariant natural killer T (iNKT) cells mediate sepsis-induced end-organ changes and immune responses, including macrophage bacterial phagocytosis, a finding regulated by the check point protein program cell death receptor-1 (PD-1)
Externí odkaz:
https://doaj.org/article/dc1b09a4299145b6b9b3047e9311dd37
Publikováno v:
The American Journal of Surgery. 221:1018-1023
Background In order to better characterize outcomes of palliative surgery (PS), we evaluated patients that experienced top quartile survival to elucidate predictors of high impact PS. Methods All PS performed on advanced cancer patients from 2003 to
Autor:
Thomas J. Miner, Eleanor A. Fallon
Publikováno v:
The American Surgeon. 86:1473-1477
Regardless of the anatomic site of malignant bowel obstruction leading to the need for palliative intervention, decisions must consider the natural history of the disease, the availability and success of nonsurgical treatments, the individual patient
Publikováno v:
Shock. 51:487-494
Therapeutic interventions to treat acute lung injury (ALI) remain largely limited to lung-protective strategies, as a real molecular pathophysiologically driven therapeutic intervention has yet to become available. While we have previously documented
Autor:
Eleanor A. Fallon, Monique E. De Paepe, Yaping Chen, Chun-Shiang Chung, Alfred Ayala, Daithi S. Heffernan
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Morbidity and mortality associated with neonatal sepsis remains a healthcare crisis. PD1−/− neonatal mice endured experimental sepsis, in the form of cecal slurry (CS), and showed improved rates of survival compared to wildtype (WT) counterparts.
Publikováno v:
American journal of surgery. 221(5)
In order to better characterize outcomes of palliative surgery (PS), we evaluated patients that experienced top quartile survival to elucidate predictors of high impact PS.All PS performed on advanced cancer patients from 2003 to 2017 were identified
Autor:
Tianzhu Tao, Alfred Ayala, Chun-Shiang Chung, Jianwen Bai, Qian Yang, Shumin Xu, Yaping Chen, Eleanor A. Fallon, Lunxian Tang
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
This study sets out to establish the comparative contribution of PD-L1 expression by pulmonary endothelial cells (ECs) and/or epithelial cells (EpiCs) to the development of indirect acute lung injury (iALI) by taking advantage of the observation that
Autor:
Alfred Ayala, Daithi S. Heffernan, Philip A. Efron, Whitney A. Young, William G. Cioffi, Eleanor A. Fallon
Publikováno v:
Surgery. 161:1387-1393
Background Sepsis and the ensuing immune dysfunction continue to be major contributors to neonatal morbidity and mortality. Neonatal sepsis also is associated with profound immune dysfunction. We have recently identified a role for a family of coinhi