Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Eleanor A Minogue"'
Autor:
Brennan J Wadsworth, Marina Leiwe, Eleanor A Minogue, Pedro P Cunha, Viktor Engman, Carolin Brombach, Christos Asvestis, Shiv K Sah-Teli, Emilia Marklund, Peppi Koivunen, Jorge L Ruas, Helene Rundqvist, Johanna T Lanner, Randall S Johnson
Publikováno v:
eLife, Vol 12 (2024)
Several metabolites have been shown to have independent and at times unexpected biological effects outside of their metabolic pathways. These include succinate, lactate, fumarate, and 2-hydroxyglutarate. 2-Hydroxybutyrate (2HB) is a byproduct of endo
Externí odkaz:
https://doaj.org/article/a2344de77b9c433ca84e766bf403fa6d
Autor:
Iosifina P. Foskolou, Pedro P. Cunha, Elena Sánchez-López, Eleanor A. Minogue, Benoît P. Nicolet, Aurélie Guislain, Christian Jorgensen, Sarantos Kostidis, Nordin D. Zandhuis, Laura Barbieri, David Bargiela, Demitris Nathanael, Petros A. Tyrakis, Asis Palazon, Martin Giera, Monika C. Wolkers, Randall S. Johnson
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113013- (2023)
Summary: 2-Hydroxyglutarate (2HG) is a byproduct of the tricarboxylic acid (TCA) cycle and is readily detected in the tissues of healthy individuals. 2HG is found in two enantiomeric forms: S-2HG and R-2HG. Here, we investigate the differential roles
Externí odkaz:
https://doaj.org/article/8bf56a3c50134fed9555ff2704dda5a3