Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Eldwin L. VanAlstyne"'
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 348
Guinea pig inferior vena cava contracted in response to leukotriene (LT)C4, LTD4, LTE4 U46619, phenylephrine, histamine, and KCl. Although LTC4, LTD4, and U46619 were the most potent agonists, active tension generated by these eicosanoids was only ab
Publikováno v:
Journal of chromatography. 579(1)
A method is described for automated on-line extraction and fractionation of plasma leukotrienes (LTs) and (5Z,8Z,10E,14Z)-(12S)-hydroxy-5,8,10,14-eicosate traenoic acid [12(S)-HETE] by reversed-phase high-performance liquid chromatography (RP-HPLC).
Publikováno v:
Biochemical pharmacology. 43(4)
We evaluated the effect of age on eicosanoid production in guinea pig blood. Heparinized blood from 7–10-day, 6-week, or 6-month-old guinea pigs was incubated with 150 μM arachidonic acid (AA) for 5 min, followed by stimulation with A23187 (20 μg
Autor:
David W. Snyder, Trafford Clarke, Penelope A. Pechous, Eldwin L. VanAlstyne, Stephen M. Spaethe
Publikováno v:
Biochemical pharmacology. 43(2)
Guinea pigs are widely used in the study of the role of leukotrienes in airway pathophysiology. Extensive research efforts have utilized this species in the development of potential therapeutic agents associated with inhibition of leukotriene product
Publikováno v:
Annals of the New York Academy of Sciences. 639