Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Eldridge N. Nartey"'
Autor:
Christopher L. Carpenter, Eldridge N. Nartey, Dominic Suarez, Elisabeth A. Minthorn, Jesus R. Medina, Louis V. LaFrance, Ralph A. Rivero, James F. Mack, Charles F. McHugh, Xinrong Tian, Dirk A. Heerding, Christina Ng Di Marco, Thomas J. Berrodin, Aishwarya Bhaskar, Biju Mangatt, William Hoi Hong Li, Brackley James, Martyr Cuthbert, Lorena A. Kallal, Michael Butticello, Jacob Rubin
Publikováno v:
Journal of Medicinal Chemistry. 64:16056-16087
Elevated expression of the c-MYC oncogene is one of the most common abnormalities in human cancers. Unfortunately, efforts to identify pharmacological inhibitors that directly target MYC have not yet yielded a drug-like molecule due to the lack of an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be3a3a04dfdce0aa0aa268d1655c5476
https://doi.org/10.1021/acs.jmedchem.1c01416
https://doi.org/10.1021/acs.jmedchem.1c01416
Autor:
Jesús R, Medina, Xinrong, Tian, William H, Li, Dominic, Suarez, James F, Mack, Louis, LaFrance, Cuthbert, Martyr, James, Brackley, Christina, Di Marco, Ralph, Rivero, Dirk A, Heerding, Charles, McHugh, Elisabeth, Minthorn, Aishwarya, Bhaskar, Jacob, Rubin, Michael, Butticello, Christopher, Carpenter, Eldridge N, Nartey, Thomas J, Berrodin, Lorena A, Kallal, Biju, Mangatt
Publikováno v:
Journal of medicinal chemistry. 64(21)
Elevated expression of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::30e906e5f811e1b96b38c311683c1ee4
https://pubmed.ncbi.nlm.nih.gov/34669409
https://pubmed.ncbi.nlm.nih.gov/34669409
Autor:
Liping Wang, Shihyun You, Ninad V. Prabhu, Hongfeng Deng, Danielle G. Smith, Jing Chai, Ginger H Tomberlin, Robert T. Nolte, James H. Nichols, G. Bruce Wisely, Edgar R. Wood, Cecil E Rise, Hamilton D. Dickson, J. David Taylor, Luz Helena Kryn, Randy K. Bledsoe, Timothy P. Sheahan, Yun Ding, Sarah Harris-Gurley, Eldridge N. Nartey, J. Brad Shotwell, Bing Xia, Philias Daka, Vince Tai
Publikováno v:
Journal of Biological Chemistry
2',5'-Oligoadenylate synthetase (OAS) enzymes and RNase-L constitute a major effector arm of interferon (IFN)-mediated antiviral defense. OAS produces a unique oligonucleotide second messenger, 2',5'-oligoadenylate (2-5A), that binds and activates RN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aef2ae03677c0520338a9d289226a214
Autor:
Octerloney B. McDonald, Robert A. Copeland, Peter J. Tummino, Denis Patrick, Mary Ann Hardwicke, Jingsong Yang, Zhihong Lai, Dashyant Dhanak, Jerry L. Adams, J. Darren Stuart, Ken A. Newlander, Kelly Anderson, Eldridge N. Nartey
Publikováno v:
Biochemical Journal. 420:259-265
The Aurora kinases AurA, B and C are serine/threonine protein kinases that play essential roles in mitosis and cytokinesis. Among them, AurB is required for maintaining proper chromosome alignment, separation and segregation during mitosis, and regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ba6e072e1bee5e3ed5459856a504c1
https://doi.org/10.1042/bj20090121
https://doi.org/10.1042/bj20090121
Autor:
Daniel F. Hassler, Robert T. Nolte, Denis Patrick, Jun Tang, Masato Nakano, Kazunori Ozawa, Maureen L. Ho, Eldridge N. Nartey, Yasushi Miyazaki, Yutaka Maeda, Hideyuki Sato, Anne T. Truesdale, Masaki Sugai, Liping Wang, Yuji Okamoto
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:1773-1778
During our effort to develop dual VEGFR2 and Tie-2 inhibitors as anti-angiogenic agents for cancer therapy, we discovered 4-amino-5-(4-((2-fluoro-5-(trifluoromethyl)phenyl)- aminocarbonylamino)phenyl)furo[2,3-d]pyrimidine (8a) possessing strong inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b824be3d8d3815226d1ad10a70e424e
https://doi.org/10.1016/j.bmcl.2006.12.077
https://doi.org/10.1016/j.bmcl.2006.12.077
Autor:
Anne T. Truesdale, Liping Wang, Jeffrey A. Stafford, James Marvin Veal, Robert T. Nolte, Victoria B. Knick, Sharon K. Rudolph, Mui Cheung, Kristen Elizabeth Nailor, Eldridge N. Nartey, Douglas M. Sammond, Rakesh Kumar
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:3519-3523
A series of dianilinopyrimidineureas demonstrate potency as VEGFR2 kinase inhibitors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6946bbbc0f2a909c27b5a7ff105ca1eb
https://doi.org/10.1016/j.bmcl.2005.05.096
https://doi.org/10.1016/j.bmcl.2005.05.096
Autor:
Kelly Anderson, Zhihong Lai, Octerloney B. Mcdonald, J. Darren Stuart, Eldridge N. Nartey, Mary Ann Hardwicke, Ken Newlander, Dashyant Dhanak, Jerry Adams, Denis Patrick, Robert A. Copeland, Peter J. Tummino, Jingsong Yang
Publikováno v:
Biochemical Journal; May2009, Vol. 420 Issue 2, p259-265, 7p