Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Eldri U Due"'
Autor:
Kristin Reiche, Katharina Kasack, Stephan Schreiber, Torben Lüders, Eldri U Due, Bjørn Naume, Margit Riis, Vessela N Kristensen, Friedemann Horn, Anne-Lise Børresen-Dale, Jörg Hackermüller, Lars O Baumbusch
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106076 (2014)
Breast cancer, the second leading cause of cancer death in women, is a highly heterogeneous disease, characterized by distinct genomic and transcriptomic profiles. Transcriptome analyses prevalently assessed protein-coding genes; however, the majorit
Externí odkaz:
https://doaj.org/article/830aa8163d0f45408734395599e8c03f
Autor:
Miriam Ragle Aure, Valeria Vitelli, Sandra Jernström, Surendra Kumar, Marit Krohn, Eldri U. Due, Tonje Husby Haukaas, Suvi-Katri Leivonen, Hans Kristian Moen Vollan, Torben Lüders, Einar Rødland, Charles J. Vaske, Wei Zhao, Elen K. Møller, Silje Nord, Guro F. Giskeødegård, Tone Frost Bathen, Carlos Caldas, Trine Tramm, Jan Alsner, Jens Overgaard, Jürgen Geisler, Ida R. K. Bukholm, Bjørn Naume, Ellen Schlichting, Torill Sauer, Gordon B. Mills, Rolf Kåresen, Gunhild M. Mælandsmo, Ole Christian Lingjærde, Arnoldo Frigessi, Vessela N. Kristensen, Anne-Lise Børresen-Dale, Kristine K. Sahlberg, OSBREAC
Publikováno v:
Breast Cancer Research, Vol 19, Iss 1, Pp 1-18 (2017)
Abstract Background Breast cancer is a heterogeneous disease at the clinical and molecular level. In this study we integrate classifications extracted from five different molecular levels in order to identify integrated subtypes. Methods Tumor tissue
Externí odkaz:
https://doaj.org/article/189f5fdfd4474ab79a5166a5fc6eff7e
Autor:
Andreas Hagen Røssevold, My Anh Tu Sveli, Xavier Tekpli, Lisa Gregusson Svartdal, Eldri U. Due, Vessela N. Kristensen, Arnoldo Frigessi, Jon Amund Kyte, Therese Sørlie, Osbreac, Daniel Nebdal, Johan Vallon-Christersson, Elin Borgen, Marie Fongaard, Tonje Lien, Hege O. Ohnstad, Bjørn Naume, Hege G. Russnes, Kristine Kleivi Sahlberg, Øystein Garred
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
How mixtures of immune cells associate with cancer cell phenotype and affect pathogenesis is still unclear. In 15 breast cancer gene expression datasets, we invariably identify three clusters of patients with gradual levels of immune infiltration. Th
Autor:
Henrik Edgren, Suvi-Katri Leivonen, Dagim Shiferaw Tadele, Olli Kallioniemi, Eldri U. Due, Merja Perälä, Kristine Kleivi Sahlberg, Vesa Hongisto, Sandra Jernström, Gunhild Mari Mælandsmo
Publikováno v:
Breast Cancer : Targets and Therapy
Jernström, S, Hongisto, V, Leivonen, S, Due, E, Tadele, D, Edgren, H, Kallioniemi, O, Perälä, M, Mælandsmo, G & Sahlberg, K 2017, ' Drug-screening and genomic analyses of HER2-positive breast cancer cell lines reveal predictors for treatment response ', Breast Cancer, vol. 9, A22, pp. 185-198 . https://doi.org/10.2147/BCTT.S115600
Jernström, S, Hongisto, V, Leivonen, S, Due, E, Tadele, D, Edgren, H, Kallioniemi, O, Perälä, M, Mælandsmo, G & Sahlberg, K 2017, ' Drug-screening and genomic analyses of HER2-positive breast cancer cell lines reveal predictors for treatment response ', Breast Cancer, vol. 9, A22, pp. 185-198 . https://doi.org/10.2147/BCTT.S115600
Sandra Jernström,1,2 Vesa Hongisto,3 Suvi-Katri Leivonen,1,2 Eldri Undlien Due,1 Dagim Shiferaw Tadele,1 Henrik Edgren,4,5 Olli Kallioniemi,4 Merja Perälä,6 Gunhild Mari Mælandsmo,2,7,8 Kristine Kleivi Sahlberg,1,9 1Department of Cancer Genetics,
Autor:
Sandra Jernström, Einar Andreas Rødland, Carlos Caldas, Jens Overgaard, Bjørn Naume, Tone Frost Bathen, Tonje Husby Haukaas, Suvi-Katri Leivonen, Rolf Kåresen, Gordon B. Mills, Arnoldo Frigessi, Gunhild Mari Mælandsmo, Valeria Vitelli, Ellen Schlichting, Vessela N. Kristensen, Marit Krohn, Hans Kristian Moen Vollan, Torill Sauer, Guro F. Giskeødegård, Eldri U. Due, Elen K. Møller, Ole Christian Lingjærde, Jan Alsner, Wei Zhao, Miriam Ragle Aure, Kristine Kleivi Sahlberg, Torben Lüders, Trine Tramm, Ida R. K. Bukholm, Anne Lise Børresen-Dale, Charles J. Vaske, Silje Nord, Jürgen Geisler, Surendra Kumar
Publikováno v:
Breast Cancer Research : BCR
Aure, M R, Vitelli, V, Jernström, S, Kumar, S, Krohn, M, Due, E U, Haukaas, T H, Leivonen, S-K, Vollan, H K M, Lüders, T, Rødland, E, Vaske, C J, Zhao, W, Møller, E K, Nord, S, Giskeødegård, G F, Bathen, T F, Caldas, C, Tramm, T, Alsner, J, Overgaard, J, Geisler, J, Bukholm, I R K, Naume, B, Schlichting, E, Sauer, T, Mills, G B, Kåresen, R, Mælandsmo, G M, Lingjærde, O C, Frigessi, A, Kristensen, V N, Børresen-Dale, A-L, Sahlberg, K K & OSBREAC 2017, ' Integrative clustering reveals a novel split in the luminal A subtype of breast cancer with impact on outcome ', Breast Cancer Research, vol. 19, no. 1, 44 . https://doi.org/10.1186/s13058-017-0812-y
Breast Cancer Research
Breast Cancer Research, Vol 19, Iss 1, Pp 1-18 (2017)
Aure, M R, Vitelli, V, Jernström, S, Kumar, S, Krohn, M, Due, E U, Haukaas, T H, Leivonen, S-K, Vollan, H K M, Lüders, T, Rødland, E, Vaske, C J, Zhao, W, Møller, E K, Nord, S, Giskeødegård, G F, Bathen, T F, Caldas, C, Tramm, T, Alsner, J, Overgaard, J, Geisler, J, Bukholm, I R K, Naume, B, Schlichting, E, Sauer, T, Mills, G B, Kåresen, R, Mælandsmo, G M, Lingjærde, O C, Frigessi, A, Kristensen, V N, Børresen-Dale, A-L, Sahlberg, K K & OSBREAC 2017, ' Integrative clustering reveals a novel split in the luminal A subtype of breast cancer with impact on outcome ', Breast Cancer Research, vol. 19, no. 1, 44 . https://doi.org/10.1186/s13058-017-0812-y
Breast Cancer Research
Breast Cancer Research, Vol 19, Iss 1, Pp 1-18 (2017)
BACKGROUND:Breast cancer is a heterogeneous disease at the clinical and molecular level. In this study we integrate classifications extracted from five different molecular levels in order to identify integrated subtypes.METHODS:Tumor tissue from 425
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e941b57fce822326c5b3a8af5b7604c
http://hdl.handle.net/11250/2460651
http://hdl.handle.net/11250/2460651
Autor:
Merja Perälä, Kristine Kleivi Sahlberg, Rami Mäkelä, Anne Lise Børresen-Dale, Olli Kallioniemi, Suvi-Katri Leivonen, Eldri U. Due
Publikováno v:
Leivonen, S-K, Sahlberg, K K, Mäkelä, R, Due, E U, Kallioniemi, O, Børresen-Dale, A-L & Perälä, M 2014, ' High-throughput screens identify microRNAs essential for HER2 positive breast cancer cell growth ', Molecular Oncology, vol. 8, no. 1, pp. 93-104 . https://doi.org/10.1016/j.molonc.2013.10.001
MicroRNAs (miRNAs) are non-coding RNAs regulating gene expression post-transcriptionally. We have characterized the role of miRNAs in regulating the human epidermal growth factor receptor 2 (HER2)-pathway in breast cancer. We performed miRNA gain-of-
Autor:
Eldri U. Due, Elda Tagliabue, Jahn M. Nesland, Anne Lise Børresen-Dale, Pedro Kringen, Aune Nehman, Neeme Tõnisson, Yun Wang, Anna Bergamaschi
Publikováno v:
BioTechniques. 39:755-761
Mutations in the tumor suppressor gene TP53 are associated with a wide range of different cancers and may have prognostic and therapeutic implications. Methods for rapid and sensitive detection of mutations in this gene are therefore required. In ord
Autor:
Evgeny N. Imyanitov, Ari Hirvonen, Anne Lise Børresen-Dale, Evgeny N. Suspitsin, Phuong Vu, Eldri U. Due
Publikováno v:
Cancer Genetics and Cytogenetics. 184:119-121
Autor:
Maija Wolf, Vesa Hongisto, Kristine Kleivi Sahlberg, Hans Kristian Moen Vollan, Kirsi Hellström, Niko Sahlberg, Henrik Edgren, Merja Perälä, Rami Mäkelä, Eldri U. Due, Anne Lise Børresen-Dale, Olli Kallioniemi
Publikováno v:
Kleivi Sahlberg, K, Hongisto, V, Edgren, H, Mäkelä, R, Hellström, K, Due, E U, Moen Vollan, H K, Sahlberg, N, Wolf, M, Børresen-Dale, A-L, Perälä, M & Kallioniemi, O 2013, ' The HER2 amplicon includes several genes required for the growth and survival of HER2 positive breast cancer cells ', Molecular Oncology, vol. 7, no. 3, pp. 392-401 . https://doi.org/10.1016/j.molonc.2012.10.012
About 20% of breast cancers are characterized by amplification and overexpression of the HER2 oncogene. Although significant progress has been achieved for treating such patients with HER2 inhibitor trastuzumab, more than half of the patients respond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe2369aa4dcd0b9d561b82317a5e9545
https://cris.vtt.fi/en/publications/929243cd-f46e-4ffe-950c-2476df62fde0
https://cris.vtt.fi/en/publications/929243cd-f46e-4ffe-950c-2476df62fde0
Autor:
Eldri U. Due, Gro Nilsen, Renathe Fjelldal, Klaus Pantel, Ida J. Schneider, Randi R. Mathiesen, Inga H. Rye, Lars Oliver Baumbusch, Jochen B. Geigl, Knut Liestøl, Sabine Riethdorf, Michael R. Speicher, Anne Lise Børresen-Dale, Elin Borgen, Anna C. Obenauf, Oliver Mauermann, Bjørn Naume, Ole Christian Lingjærde
Publikováno v:
International journal of cancer. 131(4)
The presence of disseminated tumor cells (DTCs) in bone marrow (BM) identifies breast cancer patients with less favorable outcome. Furthermore, molecular characterization is required to investigate the malignant potential of these cells. This study p