Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Eldo V Kuzhikandathil"'
Autor:
Joon H Seo, Eldo V Kuzhikandathil
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0143908 (2015)
Several studies have shown that repeated stressful experiences during childhood increases the likelihood of developing depression- and anxiety-related disorders in adulthood; however, the underlying mechanisms are not well understood. We subjected dr
Externí odkaz:
https://doaj.org/article/ab6d7328257a42f2b3e22f06d3f3285d
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49288 (2012)
The D1 dopamine receptor subtype is expressed in the brain, kidney and lymphocytes. D1 receptor function has been extensively studied and the receptor has been shown to modulate a wide range of physiological functions and behaviors. The expression of
Externí odkaz:
https://doaj.org/article/314dd79c42de4ad4bccc24902892044b
Autor:
Ankur Patel, Youhua Zhu, Eldo V Kuzhikandathil, William A Banks, Allan Siegel, Steven S Zalcman
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41623 (2012)
Soluble cytokine receptors are normal constituents of body fluids that regulate peripheral cytokine and lymphoid activity and whose levels are increased in states of immune activation. Soluble interleukin-6 receptor (sIL-6R) levels positively correla
Externí odkaz:
https://doaj.org/article/c593071c809e470d903bed8bba75d093
Autor:
Jingyuan Li, Jing Li, Xiaojun Liu, Shanshan Qin, Yanzhong Guan, Yuwei Liu, Yunhui Cheng, Xiuwen Chen, Wen Li, Shenming Wang, Ming Xiong, Eldo V. Kuzhikandathil, Jiang‐Hong Ye, Chunxiang Zhang
Publikováno v:
EMBO Molecular Medicine, Vol 5, Iss 9, Pp 1402-1414 (2013)
Abstract Alcohol addiction is a major social and health concern. Here, we determined the expression profile of microRNAs (miRNAs) in the nucleus accumbens (NAc) of rats treated with alcohol. The results suggest that multiple miRNAs were aberrantly ex
Externí odkaz:
https://doaj.org/article/19dcfd8d277c454a91707a3da0789679
Autor:
Eldo V. Kuzhikandathil, Kevin D. Beck, Torry S. Dennis, Tara P. Cominski, Samara A.M. Bobzean, Linda I. Perrotti, Richard J. Servatius
Publikováno v:
Behavioural Brain Research. 313:208-213
The Wistar-Kyoto (WKY) rat has been proposed as a model of anxiety vulnerability as it exhibits pronounced behavioral inhibition, passive avoidance, exaggerated startle response, enhanced HPA-axis activation, and active avoidance that is resistant to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79251822abe799a9c375551828fa9408
https://doi.org/10.1016/j.bbr.2016.07.017
https://doi.org/10.1016/j.bbr.2016.07.017
Autor:
Eldo V. Kuzhikandathil
Dopamine receptors, in particular the dopamine D1 receptor subtype, mediate the physiological and behavioral responses elicited by cocaine. Numerous studies have shown that acute and chronic cocaine administration alter the expression of dopamine D1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3932c9817d7ced975648cbb5efc4d32
https://doi.org/10.1016/b978-0-12-803750-8.00015-4
https://doi.org/10.1016/b978-0-12-803750-8.00015-4
Publikováno v:
Neuroscience Letters. 558:20-25
In adult mice, repeated cocaine administration induces behavioral sensitization measured as increased horizontal locomotor activity. Cocaine-induced locomotor sensitization has been well characterized in adult mice. In adult animals, the D1 dopamine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bbe3bc055f16f538fd00f7a05fa0579
https://doi.org/10.1016/j.neulet.2013.09.051
https://doi.org/10.1016/j.neulet.2013.09.051
Autor:
Shenming Wang, Jing Li, Yunhui Cheng, Yu-Wei Liu, Chunxiang Zhang, Wen Li, Xiaojun Liu, Jingyuan Li, Jiang-Hong Ye, Shanshan Qin, Eldo V. Kuzhikandathil, Chen Xiuwen, Yanzhong Guan, Ming Xiong
Publikováno v:
EMBO Molecular Medicine
Alcohol addiction is a major social and health concern. Here, we determined the expression profile of microRNAs (miRNAs) in the nucleus accumbens (NAc) of rats treated with alcohol. The results suggest that multiple miRNAs were aberrantly expressed i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4894b2b9cb5e2ff35dc3948bb37bd7cf
https://doi.org/10.1002/emmm.201201900
https://doi.org/10.1002/emmm.201201900
Publikováno v:
ACS Chemical Neuroscience. 4:940-951
The D3 dopamine receptor is a therapeutic target for treating various nervous system disorders such as schizophrenia, Parkinson's disease, depression, and addictive behaviors. The crystal structure of the D3 receptor bound to an antagonist was recent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::730ed0367714701e2c60ac6ddc6d736e
https://doi.org/10.1021/cn3002202
https://doi.org/10.1021/cn3002202
Publikováno v:
Schizophrenia bulletin. 42(5)
Receptors for antipsychotics in the hypothalamus contribute to antipsychotics-induced weight gain; however, many of these receptors are also expressed in the intestine. The role of these intestinally-expressed receptors, and their potential modulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56789c6dc89ec7e0a2958eae36dcddb4
https://pubmed.ncbi.nlm.nih.gov/27056716
https://pubmed.ncbi.nlm.nih.gov/27056716