Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Elder Granger"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Introduction: The global COVID-19 pandemic and seasonal influenza outbreaks have drawn attention to the critical need for accurate and efficient diagnostic tools.Methods: The performance of the InstaView COVID-19/Flu Ag Combo Test, which was designed
Externí odkaz:
https://doaj.org/article/a609508dc43743499aaf5d98a94d09d9
Autor:
Richard Searfoss, Punit Shah, Kennedy Ofori-Mensa, Valerie Bussberg, Vladimir Tolstikov, Bennett Greenwood, Hongyan Li, Kris Richardson, Gregory M. Miller, Corinne DeCicco, Elder Granger, Leonardo O. Rodrigues, Eric M. Grund, A. James Moser, Rangaprasad Sarangarajan, Niven R. Narain, Michael A. Kiebish
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Cancer biomarker discovery is critically dependent on the integrity of biofluid and tissue samples acquired from study participants. Multi-omic profiling of candidate protein, lipid, and metabolite biomarkers is confounded by timing and fast
Externí odkaz:
https://doaj.org/article/ff0d3450a9874c839c54f477fb0fae21
Autor:
Michael A. Kiebish, Poornima Tekumalla, Shobha Ravipaty, Albert Dobi, Shiv Srivastava, Wenfang Wu, Saurabh Patil, Tracey Friss, Allison Klotz, Alagarsamy Srinivasan, Jennifer Cullen, Inger L. Rosner, Amina Ali, Sandra Laszlo, Michele Petrovic, Neil Fleshner, Jeonifer Garren, Greg Miller, Nischal Mahaveer Chand, Leonardo O. Rodrigues, Elder Granger, Mark D. Kellogg, Shen Luan, Eleftherios Diamandis, Viatcheslav R. Akmaev, Rangaprasad Sarangarajan, Chas Bountra, Stephen J. Freedland, David G. McLeod, Niven R. Narain
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Prostate-specific antigen (PSA) screening for prostate cancer (PCa) is limited by the lack of specificity but is further complicated in the benign prostatic hyperplasia (BPH) population which also exhibit elevated PSA, representing a clear u
Externí odkaz:
https://doaj.org/article/30b5d2f52b594d5593705963e0ea8e51
Autor:
Tulin Dadali, Anne R. Diers, Shiva Kazerounian, Senthil K. Muthuswamy, Pallavi Awate, Ryan Ng, Saie Mogre, Carrie Spencer, Katerina Krumova, Hannah E. Rockwell, Justice McDaniel, Emily Y. Chen, Fei Gao, Karl T. Diedrich, Vijetha Vemulapalli, Leonardo O. Rodrigues, Viatcheslav R. Akmaev, Khampaseuth Thapa, Manuel Hidalgo, Arindam Bose, Vivek K. Vishnudas, A. James Moser, Elder Granger, Michael A. Kiebish, Stephane Gesta, Niven R. Narain, Rangaprasad Sarangarajan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Reactive oxygen species (ROS) are implicated in triggering cell signalling events and pathways to promote and maintain tumorigenicity. Chemotherapy and radiation can induce ROS to elicit cell death allows for targeting ROS pathways for effec
Externí odkaz:
https://doaj.org/article/e79d9a1528004582b599d5a67e27bffe
Autor:
Michael A. Kiebish, Jennifer Cullen, Prachi Mishra, Amina Ali, Eric Milliman, Leonardo O. Rodrigues, Emily Y. Chen, Vladimir Tolstikov, Lixia Zhang, Kiki Panagopoulos, Punit Shah, Yongmei Chen, Gyorgy Petrovics, Inger L. Rosner, Isabell A. Sesterhenn, David G. McLeod, Elder Granger, Rangaprasad Sarangarajan, Viatcheslav Akmaev, Alagarsamy Srinivasan, Shiv Srivastava, Niven R. Narain, Albert Dobi
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-10 (2020)
Abstract Background Predicting the clinical course of prostate cancer is challenging due to the wide biological spectrum of the disease. The objective of our study was to identify prostate cancer prognostic markers in patients ‘sera using a multi-o
Externí odkaz:
https://doaj.org/article/4c95a22fa38048aeaa9f5cfd28ba10df
Autor:
Michael A. Kiebish, Punit Shah, Rangaprasad Sarangarajan, Vivek K. Vishnudas, Stephane Gesta, Poornima K. Tekumalla, Chas Bountra, Elder Granger, Eric Schadt, Leonardo O. Rodrigues, Niven R. Narain
Publikováno v:
Applied Sciences, Vol 11, Iss 6, p 2466 (2021)
The emergence of COVID-19 progressed into a global pandemic that has functionally put the world at a standstill and catapulted major healthcare systems into an overburdened state. The dire need for therapeutic strategies to mitigate and successfully
Externí odkaz:
https://doaj.org/article/7476e5f3f1f842eeab9563018faaa469
Autor:
Guisong Wang, Punit Shah, Rick Searfoss, J. Leigh Fantacone-Campbell, Jeffrey A. Hooke, Brenda Deyarmin, Rebecca N. Zingmark, Stella Somiari, Jianfang Liu, Leonid Kvecher, Lori A. Sturtz, Praveen-Kumar Raj-Kumar, Elder Granger, Linda Vahdat, Niven R. Narain, Mary L. Cutler, Rangaprasad Sarangarajan, Hai Hu, Michael A. Kiebish, Albert J. Kovatich, Craig D. Shriver
Publikováno v:
Cancer Research. 82:P1-05
Introduction: In clinical practice, immunohistochemistry (IHC) is combined with clinicopathologic information to stratify patients into subtypes and guide treatment decisions. In our mass spectrometry study of 116 breast cancers (BrCAs), we identifie
Autor:
Craig D. Shriver, Punit P. Shah, Elder Granger, Rangaprasad Sarangarajan, Lori A. Sturtz, Hai Hu, Rebecca N. Zingmark, Rick Searfoss, Niven R. Narain, Brenda Deyarmin, Jianfang Liu, Albert J. Kovatich, Guisong Wang, Praveen-Kumar Raj-Kumar, Linda T. Vahdat, Leonid Kvecher, Mary Lou Cutler, Stella Somiari, Michael A. Kiebish, J. Leigh Fantacone Campbell, Jeffrey A. Hooke
Publikováno v:
Cancer Research. 81:PS5-34
Introduction: Improving stratification of breast cancer (BC) patients based on molecular signatures for treatment responses and clinical outcomes is a critical unmet need. Currently, endocrine therapy is first-line for hormone receptor positive (HR+)
Autor:
Nischal Mahaveer Chand, Poornima K. Tekumalla, Albert Dobi, Amina Ali, Gregory M. Miller, Juan J. Aristizabal-Henao, Elder Granger, Stephen J. Freedland, Shiv Srivastava, Jose Arturo Rodriguez Rivera, Arturo Mendoza, David G. McLeod, Niven R. Narain, Michael A. Kiebish
Publikováno v:
Cancer Research. 83:2196-2196
Prostate cancer represents a significant health risk to aging men, in which diagnostic challenges pose major issues with identification of indolent and or aggressive cancers. Prostate cancer screening is driven by prostate specific antigen (PSA), how
Autor:
Gregory M. Miller, J. Austin Ellis, Rangaprasad Sarangarajan, Amay Parikh, Leonardo O. Rodrigues, Can Bruce, Nischal Mahaveer Chand, Steven R. Smith, Kris Richardson, Raymond Vazquez, Michael A. Kiebish, Chandran Haneesh, Elder Granger, Judy Holtz, Jacob Hinkle, Niven R. Narain, Bret Goodpaster, Jeremy C. Smith, Daniel S. Lupu
Publikováno v:
Drugs - real world outcomes. 9(3)
The COVID-19 pandemic generated a massive amount of clinical data, which potentially hold yet undiscovered answers related to COVID-19 morbidity, mortality, long-term effects, and therapeutic solutions.The objectives of this study were (1) to identif