Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Elden P, Swindell"'
Autor:
Leonidas C. Platanias, Jessica K. Altman, Thomas V. O'Halloran, Benoit Viollet, Elden P. Swindell, Dhaval Nanavati, Ruth Serrano, Ewa M. Kosciuczuk, Elspeth M. Beauchamp
Supplementary Figure Legends. Supplementary Figure 1: Targeted disruption of AMPKα1/2 does not affect arsenicinducible phosphorylation of AKT at Ser473. Supplementary Figure 2: As- Biotin binds to AMPKα as measured by mass spectroscopy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3166eab3b8ad1da64ea39f92c69e5504
https://doi.org/10.1158/1535-7163.22501923
https://doi.org/10.1158/1535-7163.22501923
Autor:
Ernst Lengyel, Thomas V. O'Halloran, Andrew P. Mazar, Katja Gwin, Richard W. Ahn, Patrick L. Hankins, Anirban K. Mitra, Elden P. Swindell, Hilary A. Kenny, Yilin Zhang
The urokinase system is overexpressed in epithelial ovarian cancer cells and is expressed at low levels in normal cells. To develop a platform for intracellular and targeted delivery of therapeutics in ovarian cancer, we conjugated urokinase plasmino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91dcc021f22bbd52a1f8bc6ac81bee48
https://doi.org/10.1158/1535-7163.c.6536449
https://doi.org/10.1158/1535-7163.c.6536449
Autor:
Ernst Lengyel, Thomas V. O'Halloran, Andrew P. Mazar, Katja Gwin, Richard W. Ahn, Patrick L. Hankins, Anirban K. Mitra, Elden P. Swindell, Hilary A. Kenny, Yilin Zhang
PDF - 469KB, Supplementary Materials & Methods; Supplementary Figure S1: Specific uptake of ATN-291-NB(Ni,As) in ovarian cancer cells; Supplementary Figure S2: Confocal studies of early apoptosis in HeyA8 cells treated with nanobins; Supplementary Fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6442af9175f66c3f9799f8cb113eba71
https://doi.org/10.1158/1535-7163.22500427
https://doi.org/10.1158/1535-7163.22500427
Autor:
Thomas V. O'Halloran, Vincent L. Cryns, Vamsi Parimi, Elden P. Swindell, Meera R. Raja, Anil K. Patri, Jeffrey D. Clogston, Stephan T. Stern, Haimei Chen, Feng Chen, Richard W. Ahn
Supplementary Data from A Novel Nanoparticulate Formulation of Arsenic Trioxide with Enhanced Therapeutic Efficacy in a Murine Model of Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4450b1fd859cb0b60dfcf9cb1811821b
https://doi.org/10.1158/1078-0432.22442936
https://doi.org/10.1158/1078-0432.22442936
Autor:
Thomas V. O'Halloran, Vincent L. Cryns, Vamsi Parimi, Elden P. Swindell, Meera R. Raja, Anil K. Patri, Jeffrey D. Clogston, Stephan T. Stern, Haimei Chen, Feng Chen, Richard W. Ahn
Purpose: The clinical success of arsenic trioxide (As2O3) in hematologic malignancies has not been replicated in solid tumors due to poor pharmacokinetics and dose-limiting toxicity. We have developed a novel nanoparticulate formulation of As2O3 enca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ff2b9bd930deb0bb614fcd828ebe35
https://doi.org/10.1158/1078-0432.c.6519557.v1
https://doi.org/10.1158/1078-0432.c.6519557.v1
Autor:
Tiziano Marzo, Andrew P. Mazar, Giarita Ferraro, Richard W. Ahn, Luigi Messori, Sara Abuhadba, Đenana Miodragović, Thomas V. O'Halloran, Antonello Merlino, Abraham Bogachkov, Elden P. Swindell
Publikováno v:
Journal of the American Chemical Society. 141:6453-6457
Arsenoplatins are adducts of two chemically important anticancer drugs, cisplatin and arsenic trioxide, that have a Pt(II) bond to an As(III) hydroxide center. Screens of the NCI-60 human tumor cell lines reveal that arsenoplatin-1 (AP1), [Pt(μ-NHC(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57634f4b6dd32259a12032ce754e997f
https://doi.org/10.1021/jacs.8b13681
https://doi.org/10.1021/jacs.8b13681
Autor:
Benjamin A Gilston, Suning Wang, Mason D Marcus, Mónica A Canalizo-Hernández, Elden P Swindell, Yi Xue, Alfonso Mondragón, Thomas V O'Halloran
Publikováno v:
PLoS Biology, Vol 12, Iss 11, p e1001987 (2014)
Commensal microbes, whether they are beneficial or pathogenic, are sensitive to host processes that starve or swamp the prokaryote with large fluctuations in local zinc concentration. To understand how microorganisms coordinate a dynamic response to
Externí odkaz:
https://doaj.org/article/f3850d6e0af944b6981c9546c2fcd0fc
Autor:
Alexander Koshkaryev, Wiam Bshara, Jason E. Cain, Dmitri B. Kirpotin, Walid S. Kamoun, Elden P. Swindell, Troy Bloom, Daryl C. Drummond, Carl Morrison, Suresh K. Tipparaju, Zhaohua Richard Huang, Mari Mino-Kenudson, Minh T. Pham, Irawati Kandela, Vasileios Askoxylakis, Christine Pien, Alena Zalutskaya, Lia Luus, James D. Marks
Publikováno v:
Pharmaceutics, vol 12, iss 10
Pharmaceutics
Pharmaceutics, Vol 12, Iss 996, p 996 (2020)
Volume 12
Issue 10
Pharmaceutics
Pharmaceutics, Vol 12, Iss 996, p 996 (2020)
Volume 12
Issue 10
Ephrin receptor A2 (EphA2) is a member of the Ephrin/Eph receptor cell-to-cell signaling family of molecules, and it plays a key role in cell proliferation, differentiation, and migration. EphA2 is overexpressed in a broad range of cancers, and its e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7d27d2b12f3a023adf89e3b13500e33
https://escholarship.org/uc/item/8b46q0tm
https://escholarship.org/uc/item/8b46q0tm
Autor:
Elden P. Swindell, Heidi L. Weiss, B. Mark Evers, Amar Jyoti, Meenakshi Upreti, Jonathan Feddock, Ryan Chan, Thomas V. O'Halloran, Pallavi Sethi, Sara E. Johnson, Dana Napier
Publikováno v:
Oncotarget
// Meenakshi Upreti 1, 3 , Amar Jyoti 1, 3 , Sara E. Johnson 2 , Elden P. Swindell 4 , Dana Napier 3 , Pallavi Sethi 1, 3 , Ryan Chan 1 , Jonathan M. Feddock 5 , Heidi L. Weiss 3 , Thomas V. O’Halloran 4 , B. Mark Evers 3, 6 1 Department of Pharmac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed8f2b933f4dabe54094a3a51214faba
https://doi.org/10.18632/oncotarget.9490
https://doi.org/10.18632/oncotarget.9490
Autor:
Thomas V. O'Halloran, Abraham Bogachkov, Zohra Sattar Waxali, Ðenana Miodragović, Elden P. Swindell
Publikováno v:
Inorganica Chim Acta
Platinum drugs (cisplatin, oxaliplatin, and carboplatin) and arsenic trioxide are the only commercial inorganic non-radioactive anticancer drugs approved by the US Food and Drug Administration. Numerous efforts are underway to take advantage of the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ec716a1057ae25ab5c745929826b29b
https://doi.org/10.1016/j.ica.2019.119030
https://doi.org/10.1016/j.ica.2019.119030