Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Eldarina Wijaya"'
Predicting the Likelihood of Carrying a BRCA1 or BRCA2 Mutation in Asian Patients With Breast Cancer
Autor:
Boon Hong Ang, Weang Kee Ho, Eldarina Wijaya, Pui Yoke Kwan, Pei Sze Ng, Sook Yee Yoon, Siti Norhidayu Hasan, Joanna M.C. Lim, Tiara Hassan, Mei-Chee Tai, Jamie Allen, Andrew Lee, Nur Aishah Mohd Taib, Cheng Har Yip, Mikael Hartman, Swee Ho Lim, Ern Yu Tan, Benita K.T. Tan, Su-Ming Tan, Veronique K.M. Tan, Peh Joo Ho, Alexis J. Khng, Alison M. Dunning, Jingmei Li, Douglas F. Easton, Antonis C. Antoniou, Soo Hwang Teo
Publikováno v:
Journal of Clinical Oncology. 40:1542-1551
PURPOSE With the development of poly (ADP-ribose) polymerase inhibitors for treatment of patients with cancer with an altered BRCA1 or BRCA2 gene, there is an urgent need to ensure that there are appropriate strategies for identifying mutation carrie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1830af820964f59029821bd637f61735
https://doi.org/10.1200/jco.21.01647
https://doi.org/10.1200/jco.21.01647
Autor:
Boon Hong, Ang, Weang Kee, Ho, Eldarina, Wijaya, Pui Yoke, Kwan, Pei Sze, Ng, Sook Yee, Yoon, Siti Norhidayu, Hasan, Joanna M C, Lim, Tiara, Hassan, Mei-Chee, Tai, Jamie, Allen, Andrew, Lee, Nur Aishah Mohd, Taib, Cheng Har, Yip, Mikael, Hartman, Swee Ho, Lim, Ern Yu, Tan, Benita K T, Tan, Su-Ming, Tan, Veronique K M, Tan, Peh Joo, Ho, Alexis J, Khng, Alison M, Dunning, Jingmei, Li, Douglas F, Easton, Antonis C, Antoniou, Soo Hwang, Teo
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 40(14)
With the development of poly (ADP-ribose) polymerase inhibitors for treatment of patients with cancer with an alteredIn this study, we built a new model (Asian Risk Calculator) for estimating the likelihood of carrying a pathogenic variant inAsian Ri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::656a0a47ecead742ff4123893d6d76ed
https://pubmed.ncbi.nlm.nih.gov/35143328
https://pubmed.ncbi.nlm.nih.gov/35143328
Autor:
Joanna Lim, Rick A. C. M. Boonen, Milan Sharma, Ern Yu Tan, Craig Luccarini, Su-Ming Tan, Jingmei Li, Douglas F. Easton, Sabine Knaup, Benita Kiat Tee Tan, Soo Hwang Teo, Weang Kee Ho, Alison M. Dunning, Chan Eng Chong, Shivaani Mariapun, Kartini Rahmat, Sara Carvalho, Rob M. van Dam, Mee Hoong See, Eldarina Wijaya, Pei Sze Ng, Caroline Baynes, Swee Ho Lim, Antonis C. Antoniou, Sook-Yee Yoon, Haico van Attikum, Mikael Hartman, Cheng Har Yip, Nur Aishah Taib, Veronique Kiat-Mien Tan
Publikováno v:
Journal of Medical Genetics. BMJ PUBLISHING GROUP
Journal of Medical Genetics
Journal of Medical Genetics
BackgroundRare protein-truncating variants (PTVs) in partner and localiser of BRCA2 (PALB2) confer increased risk to breast cancer, but relatively few studies have reported the prevalence in South-East Asian populations. Here, we describe the prevale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::648d9944879181cb2e14eb769eb5b278
https://doi.org/10.1136/jmedgenet-2020-107471
https://doi.org/10.1136/jmedgenet-2020-107471
Autor:
Douglas F. Easton, Jingmei Li, Eldarina Wijaya, Ching Wan Chan, Alison M. Dunning, Min Hyuk Lee, Veronique Kiak Mien Tan, Shaik Ahmad Buhari, Ern Yu Tan, Soo-Chin Lee, Sue K. Park, Yirong Sim, Jong Won Lee, Mikael Hartman, Jaime Chin Mui Seah, Swee Ho Lim, Peh Joo Ho, Su-Ming Tan, Chi Wei Mok, Suniza Jamaris, Cheng Har Yip, Benita Kiat Tee Tan, Weang Kee Ho, Alexis Jiaying Khng, Nur Aishah Mohd-Taib, Wai Peng Lee, Elaine Hsuen Lim, Evan Woo, Geok Hoon Lim, Juliana J. C. Chen, Marjanka K. Schmidt, Soo Hwang Teo, Patrick M. Y. Chan, Hui Wen Loh, Joanne Ngeow, Fuh Yong Wong, Mei Chee Tai, Sung-Won Kim
Publikováno v:
Genome Medicine
Genome Medicine, Vol 13, Iss 1, Pp 1-14 (2021)
Genome Medicine, Vol 13, Iss 1, Pp 1-14 (2021)
Background Mutations in certain genes are known to increase breast cancer risk. We study the relevance of rare protein-truncating variants (PTVs) that may result in loss-of-function in breast cancer susceptibility genes on tumor characteristics and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ccd90c0ded5cf3c130cddbbbb4e4ad
https://pubmed.ncbi.nlm.nih.gov/34857041
https://pubmed.ncbi.nlm.nih.gov/34857041
Autor:
Pei Sze, Ng, Rick Acm, Boonen, Eldarina, Wijaya, Chan Eng, Chong, Milan, Sharma, Sabine, Knaup, Shivaani, Mariapun, Weang Kee, Ho, Joanna, Lim, Sook-Yee, Yoon, Nur Aishah, Mohd Taib, Mee Hoong, See, Jingmei, Li, Swee Ho, Lim, Ern Yu, Tan, Benita Kiat-Tee, Tan, Su-Ming, Tan, Veronique Kiat-Mien, Tan, Rob Martinus, van Dam, Kartini, Rahmat, Cheng Har, Yip, Sara, Carvalho, Craig, Luccarini, Caroline, Baynes, Alison M, Dunning, Antonis, Antoniou, Haico, van Attikum, Douglas F, Easton, Mikael, Hartman, Soo Hwang, Teo
Publikováno v:
Journal of medical genetics. 59(5)
Rare protein-truncating variants (PTVs) in partner and localiser of BRCA2 (Mutation testing was performed on germline DNA (n=15 768) using targeted sequencing panels. The functional impact of missense variants was tested in mouse embryonic stem cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::572839743e475ed4a963c58eb7c3b99e
https://pubmed.ncbi.nlm.nih.gov/33811135
https://pubmed.ncbi.nlm.nih.gov/33811135
Autor:
Eldarina Wijaya, Wei Xiong Wen, Kah Nyin Lai, Jamie Allen, Craig Luccarini, Joanna Lim, Min Min Tan, Shivaani Mariapun, Cheng Har Yip, Nur Aishah Mohd Taib, Alison Dunning, Douglas Easton, Soo Hwang Teo
Publikováno v:
Advances in Modern Oncology Research, Vol 3, Iss 6 (2017)
Background: To ascertain the contribution of germline alterations in BRCA1 and BRCA2 in an unselected cohort of Asian breast cancer patients and healthy controls. Methods: Two thousand five hundred and ninety-two invasive breast cancer patients and 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::a2a05c7e59738036ddb9ae3a44ae21c8
http://advmodoncolres.com/index.php/AMOR/article/view/263
http://advmodoncolres.com/index.php/AMOR/article/view/263
Autor:
Chan-Eng Chong, Susan L. North, Soo Hwang Teo, Tiara Hassan, Ranabir Das, Mikael Hartman, Rob M. van Dam, Aravind Ravichandran, Susan W. Reid, Teresa Sullivan, Joanna Lim, Douglas F. Easton, Mybrca Investigators, Jingmei Li, Farhana Fadzli, Eswary Thirthagiri, Shyam K. Sharan, Sgbcc Investigators, Kajal Biswas, Eldarina Wijaya, Cheng Har Yip, Stacey Stauffer, Nur Aishah Taib, Eileen Southon
Publikováno v:
Hum Mutat
Human Mutation
Human Mutation
The discovery of high-risk breast cancer susceptibility genes, such as Breast cancer associated gene 1 (BRCA1) and Breast cancer associated gene 2 (BRCA2) has led to accurate identification of individuals for risk management and targeted therapy. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d1e68d9c077ef70499f5fba7822b05a