Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Eldad Ben Ishay"'
Publikováno v:
Bio-Algorithms and Med-Systems. 10:169-193
The protein folding problem would be considered “solved” when it will be possible to “read genes”, i.e., to predict the native fold of proteins, their dynamics, and the mechanism of fast folding based solely on sequence data. The long-term go
Publikováno v:
Journal of Molecular Biology. 385:1230-1242
Most globular protein chains, when transferred from high to low denaturant concentrations, collapse instantly before they refold to their native state. The initial compaction of the protein molecule is assumed to have a key effect on the folding path
Publikováno v:
Biochimica et biophysica acta. 1853(4)
Mechanotransduction describes how a cell senses and interacts with its environment. The concept originated in adhesion biology where adhesion receptors, integrins, facilitate force transmission between the extracellular matrix and the intracellular a
Publikováno v:
Biochemistry. 53(19)
The nature of the earliest steps of the initiation of the folding pathway of globular proteins is still controversial. To elucidate the role of early closure of long loop structures in the folding transition, we studied the folding kinetics of subdom
Autor:
Daniel Levner, Almogit Abu-Horowitz, Yaniv Amir, Ido Bachelet, Shmulik Ittah, Eldad Ben-Ishay
Publikováno v:
Nature nanotechnology
Biological systems are collections of discrete molecular objects that move around and collide with each other. Cells carry out elaborate processes by precisely controlling these collisions, but developing artificial machines that can interface with a
Publikováno v:
Journal of Visualized Experiments.
Nucleic acids are astonishingly versatile. In addition to their natural role as storage medium for biological information(1), they can be utilized in parallel computing(2,3) , recognize and bind molecular or cellular targets(4,5) , catalyze chemical
Autor:
Eldad Ben-Ishay, Ma'ayan Ben-Dalak, Gil Rahamim, Elisha Haas, Anastasia Shulman, Tomer Orevi, Dan Amir, Sivan Gershonov, Gershon Hazan
Publikováno v:
Biophysical Journal. 104(2)
We hypothesize that few non-local interactions are effective in the early phases of the folding transition prior to the cooperative transition. These interactions loosely stabilize few closed loops which form the folding noncontiguous nucleus, reduce
Publikováno v:
The Review of scientific instruments. 83(8)
The information obtained by studying fluorescence decay of labeled biopolymers is a major resource for understanding the dynamics of their conformations and interactions. The lifetime of the excited states of probes attached to macromolecules is in t
Publikováno v:
Journal of molecular biology. 423(4)
The rate of folding of globular proteins depends on specific local and nonlocal intramolecular interactions. What is the relative role of these two types of interaction at the initiation of refolding? We address this question by application of a “d