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In vitro antimicrobial activity of ceftolozane/tazobactam against P. aeruginosa and other non-fermenting gram-negative organisms in adults with cystic fibrosis

Autor: Gramegna, A, Millar, B C, Blasi, F, Elborn, J S, Downey, D G, Moore, J E

Publikováno v: Gramegna, A, Millar, B C, Blasi, F, Elborn, J S, Downey, D G & Moore, J E 2018, ' In vitro antimicrobial activity of ceftolozane/tazobactam against P. aeruginosa and other non-fermenting gram-negative organisms in adults with cystic fibrosis ', Journal of global antimicrobial resistance . https://doi.org/10.1016/j.jgar.2018.03.002

INTRODUCTION: Pulmonary exacerbations in people with Cystic Fibrosis (CF), with chronic Gram-negative pathogens, are associated with reduced survival. These pathogens are usually treated with repeated courses of systemic antibiotics. However there is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2607::c8f30caa25d98700a895f3b5ff38da1b
https://pure.qub.ac.uk/en/publications/3f0ee4b5-d688-4757-9c41-254bdb60f4b6

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Induction of the inflammatory regulator A20 by gibberellic acid in airway epithelial cells

Autor: Reihill, J. A., Malcomson, B, Bertelsen, A., Cheung, S, Czerwiec, Agnieszka, Barsden, R, Elborn, J S, Dürkop, H, Hirsch, B, Ennis, M, Kelly, C, Schock, B C

Publikováno v: Reihill, J A, Malcomson, B, Bertelsen, A, Cheung, S, Czerwiec, A, Barsden, R, Elborn, J S, Dürkop, H, Hirsch, B, Ennis, M, Kelly, C & Schock, B C 2016, ' Induction of the inflammatory regulator A20 by gibberellic acid in airway epithelial cells ', British Journal of Pharmacology, vol. 173, no. 4, pp. 778-789 . https://doi.org/10.1111/bph.13200

BACKGROUND AND PURPOSE: NF-κB-driven inflammation is negatively regulated by the zinc finger protein A20. Gibberellic acid (GA3 ) is a plant-derived diterpenoid with documented anti-inflammatory activity, which is reported to induce A20-like zinc fi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2607::16624bd1dd687c1692c0e55074bbed43
https://pure.qub.ac.uk/en/publications/induction-of-the-inflammatory-regulator-a20-by-gibberellic-acid-in-airway-epithelial-cells(2408dd6c-a90d-4674-97e7-a8a7d4a79c48).html